Title: Study of preparation of rabbit model with VX-2 carcinoma in liver
Abstract: Objective:To study the methods of preparing the rabbit model with VX-2 carcinoma in liver used in the experimental radiology and evaluate the original growth rate of each group.Methods: 38 New-Zealand white rabbits were divided into 3 groups.15 New-Zealand white rabbits were inoculated with suspension with Ultrasound transduce,13 were inoculated with suspension by laparotomy and 10 were inoculated with VX-2 carcinoma in the liver by laparotomy implantation.All were inoculated in the left lobe of the liver and examined by plain and dual-phase enhanced CT scan and MRI plain scan respectively in 1 week,2 weeks,3 weeks,4 weeks,and 5 weeks later.The original growth rate of VX-2 carcinoma in each group was calculated.Results: VX-2 carcinoma in liver was found successfully in ten rabbits of both Group A and Group B;for Group C,VX-2 carcinoma in liver was found successfully in seven rabbits.Conclusion: The original growth rate of VX-2 carcinoma is high by the methods in all the groups,and experimental period is short.The methods are effective for the research of liver neoplasm.
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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