Title: The application of heart-type fatty acid binding protein in diabetic myocardial infarction
Abstract:OBJECTIVE To explore the value of the application for heart-type fatty acid binding protein in diabetic myocardial infarction. METHODS 30 cases of diabetes associated with myocardial infarction in our...OBJECTIVE To explore the value of the application for heart-type fatty acid binding protein in diabetic myocardial infarction. METHODS 30 cases of diabetes associated with myocardial infarction in our hospital from February 2010 to October 2011 were chosen as the observation group. 30 diabetic patients without myocardial infarction in the same period were chosen as control group. The solid-phase sandwich ELISA was used to measure the plasma H-FABP levels, determine cardiac troponin I (cTnI) and creatine kinase isoenzyme MB (CK-MB) level after the onset of 30min, 1.0h, 4h, 6h, 12h in observation group and control group. The diagnostic accuracy rates of the two groups were compared. RESULTS The number of patients with multivessel disease and hospital case fatality rate in the observation group was significantly higher than that of the control group.The single -vessel disease ratio and left ventricular ejection fraction in the observation group was significantly lower than the control group, the difference was significant (P﹤0.05). In the observation group, 6 hours after onset of diabetic AMI incidence, diagnostic rate of H-FABP was 93.33% (28/30) higher than the diagnosis rate of cTnI and CK-MB, the difference was statistically significant (P﹤0.05). H-FABP increased significantly in 4.0 h after the onset of diabetes AMI, the success rate of improving the prognosis and thrombolytic therapy increased by 30%. CONCLUSION H-FABP in diabetic patients with AMI not only has the value of early diagnosis, can also serve as an important indicator to judge the short-term prognosis, it is worthy of be drawn.Read More
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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