Title: Effect of Tongxinluo Capsule Combined with Trimetazidine in Hypersensitive C-reactive protein and Blood Lipid for Patients with Angina Pectoris After PCI
Abstract: Objective To observe the effect of Tongxinluo capsule combined with Trimetazidine in hypersensitive C-reactive protein,blood lipid and clinical effects for Patients with angina pectoris(AP)after PCI.Methods 80 cases of patients with AP after PCI were divided randomly into treatment group(n=40)and control group(n=40),both groups were treated with aspirin,clopidogrel,nitrate esters,low molecular weight heparin,β-blockers,calcium channel antagonist and statins etc.The treatment group was given Tongxinluo capsule combined with Trimetazidine in addition.After 4 weeks then to observe the improvement of symptom and the changes of hypersenstivity C-reactive protein and blood lipid.Results After 4 weeks of treatment the total effective rate of the two groups was respectiv ely 90.00%and 67.50%,the treatment group was better than the control group obviously(P0.01).In the two group the serum levels of hs-CRP were reduced after treatment,especially in treatment group(P0.05).The levels of TC,TG and LDL-C of patients were significantly decreased in the two group(P0.05),Reduction of TC and LDL-C in the treatment group was better than the control group obviously(P0.05).During the treatment there were no obvious adverse reactions in the treatment group.Conclusion Tongxinluo capsule combined with Trimetazidine can improve the clinical symptom of patients with AP after PCI,inhibit the inflammatory response,adjusting blood lipid and preventing rupture of plaque.They are safe,effective medicines in the adjuvant therapy of AP after PCI.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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