Title: Effect of Tongxinluo capsule on homocysteine in patients with angina pectoris and efficacy of this herbal capsule
Abstract: Objective To observe the effect of Tongxinluo capsule on homocysteine (HCY) in patients with stable angina pectoris and the clinical efficacy of this Chinese medicine. Methods Sixty-two patients were assigned to receive routine therapy alone (31 patients, control group) or Tongxinlou capsule in addition to routine therapy (31 patients, study group) for two months. The changes of HCY and lipids were determined and the efficacy of the capsule was evaluated in two groups after treatment. Results Serum HCY level was decreased significantly in the study group (P 0.01). Levels of total cholesterol, low density lipoprotein cholesterol, and triglyceride were markedly decreased (P 0.05) and level of high density lipoprotein cholesterol was elevated (P 0.01) in both group. The changes were more obvious in the study group (P 0.05). The efficacy rate differed significantly between the two groups (96.8% in the study group vs. 71.0% in the control group, P 0.01). Conclusions Tongxinluo can effectively relieve the symptoms of stable angina pectoris. It has an effect on lowering HCY level, regulating blood lipids, and improving the vascular endothelial function.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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