Title: Tongxinluo Jiaonang in Treatment of 42 Cases of Coronary Heart Disease and Angina Pectoris
Abstract: Objective: To evaluate and analyze the clinical efficacy and safety of Tongxinluo Jiaonang for the treatment of coronary heart disease( CHD) and angina pectoris. Methods: 86 cases of CHD were randomly grouped 44 cases in the control group and 42 cases in the treatment group. The control group used isosorbide mononitrate 20 mg,2 times per day and the treatment group was treated with Tongxinluo Jiaonang,4 Jiaonangs for each time,3 times per day. Two groups were treated for continuous 14 d. The improvement of clinical angina and ECG,blood lipids,TCM syndrome total score changes and adverse reactions were compared after treatment. Results: The treatment group's ECG and angina pectoris improved efficiencies were 85. 71%( 36 /42) and80. 95%( 34 /42),which were significantly higher than70. 45%( 31 /44) and 63. 64%( 28 /44) in the control group( P 0. 05). After treatment,Two groups' TG and TC and LDL-C levels were significantly decreased compared with those before treatment and HDL-C compared with those before treatment were significantly increased,but the treatment group' s improved more obviously( P 0. 05). After the treatment,TCM syndrome total score was( 6. 17 ± 2. 79),significantly lower than( 15. 12± 2. 39) before treatment( P 0. 05). Two groups had no adverse reactions and liver and kidney function tests were normal.Conclusion: Angina pectoris of coronary heart disease can be treated by Tongxinluo Jiaonang treatment,which can effectively improve the blood lipid level in patients with atherosclerosis and improve the clinical patients with chest pain and other symptoms and reduce the symptom scores with no adverse reaction. Therefore,Tongxinluo Jiaonang is a safe and effective drug for treatment.
Publication Year: 2015
Publication Date: 2015-01-01
Language: en
Type: article
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Cited By Count: 2
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