Title: Clinical observation of rosiglitazone for type 2 diabetes mellitus
Abstract: Objective To observe the effect,safty and adverse effect of rosiglitazone to improve insulin resistance and β cell function for singleness and combination therapy in patients with type 2 diatetes mellitus. Methods In 108 patients whose glucose level did not reach the criteria according the 1999 WHO diagnostic criteria,30 cases were given diet and sport treatment strictly for 3 weeks,21 cases were given insulin,and 57 cases were given two oral drugs all for 12 weeks.All these 108 cases were given 4 mg rosiglitazone once a day.Rusults Six cases were excluded. The glucose levels were decreased 35%, HbA1C 1.5%, HOMA IR 50%, and β cell function was increased 53% before and after treatment. Conclusion Single rosiglitazone or combined with orgal drugs and insulin can decrease glucose level and increase insulin sensitivity with no obvious adverse effect.;
Publication Year: 2004
Publication Date: 2004-01-01
Language: en
Type: article
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