Title: The evaluation of therapeutic effect of Rosiglitazone combined with Metformin in the treatment of type 2 diabetes
Abstract: Objective: To explore the therapeutic effect of Rosiglitazone combined with Metformin in the treatment of type 2 diabetes.Methods: 60 patients who were diagnosed type 2 diabetes were given Rosiglitazone combined with Metformin therapy.FBG,2 h BG,HbA1c,TC,TG,insulin resistance index,insulin sensitivity index before and after the treatment,ad-verse reaction conditions were observed.Results: 60 patients after treatment FBG,2 h postprandial blood sugar,HbA1c,TC,TG level and insulin resistance index significantly decreased compared with before treatment(P0.05).After the treat-ment insulin sensitivity index significantly increased compared with before treatment(P0.05).4 cases of patients had hy-poglycemia,2 cases of lower limb edema,1 case of gastrointestinal reaction,adverse reaction rate was 11.7%.Conclusion: Rosiglitazone combined with Metformin for type 2 diabetes patients can effectively reduce blood glucose levels,improve blood lipid metabolism and insulin resistance and adverse reaction is less.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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