Title: Study of relationship between large artery distensibility and left ventricular hypertrophy in patients with essential hypertension
Abstract: Objective To evaluate the relationship between large artery distensibility and left ventricular hypertrophy in hypertension. Methods Automatic pulse wave velocity (PWV) measurement system and two dimensional echocardiography were applied to examine carotid femoral PWV and left ventricular structure respectively. PWV was used as an index to reflect large artery distensibility; interventricular septal thickness, left ventricle posterior wall thickness, and left ventricular mass index were defined as indices for left ventricular hypertrophy; relative left ventricle thickness as an index to evaluate left ventricular concentric remodeling. Results PWV was higher in patients with left ventricular hypertrophy than that in patients without left ventricular hypertrophy (11 52±2 45 m/s vs 10 80±1 95 m/s, P = 0 001 3). There were no significant difference in PWV between patients with left ventricular concentric remodeling and without left ventricular concentric remodeling (11 10± 2 31 m/s vs 10 99±1 99, P = 0 681 6). Conclusion Large arterial distensibility decreased in patients with left ventricular hypertrophy in hypertension. The decreased large artery distensibility was an important factor that led to left ventricular hypertrophy in patients with essential hypertension.
Publication Year: 2000
Publication Date: 2000-01-01
Language: en
Type: article
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Cited By Count: 10
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