Title: Effects of left ventricular geometric patterns on cardiac function and carotid artery structure in elderly patients with essential hypertension
Abstract: Objective To observe the changes of cardiac function and carotid artery structure in elderly hypertensive patients with different left ventricular geometric patterns. Methods Seventy-eight elderly patients with essential hypertension were divided into 4 groups according to left ventricular geometric patterns by ultrasonography: normal ventricular geometry group(n=34),concentric remodeling group(n=18),concentric hypertrophy group(n=11)and eccentric hypertrophy group(n=15).The 24-h ambulatory blood pressure,left ventricular function,carotid artery intima-media thickness(IMT),hemodynamic parameters and incidence of plaque were measured and compared among groups.Results Patients in concentric hypertrophy group had higher 24-h average systolic blood pressure in comparison with those in normal ventricular geometry group and concentric remodeling group(P0.01).Patients in eccentric hypertrophy group had lower ejection function(P0.05) and higher Tei index(P0.05) in comparison with those in normal ventricular geometry group.Patients in concentric and eccentric hypertrophy groups had increased IMT in common carotid artery in comparison with those in normal ventricular geometry group(P0.05),and those in concentric hypertrophy group had increased IMT in branch of carotid artery compared with the other groups(P0.01).Besides,plaque detection rate was relatively higher in concentric hypertrophy group(54.55%),while no significant difference was observed amony groups.Conclusion Left ventricular geometric patterns lead to different changes of cardiac function and carotid artery structure in elderly patients with essential hypertension.Cardiac dysfunction was more frequent in eccentric hypertrophy,while left ventricular hypertrophy may contribute more to carotid artery remodeling.
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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