Title: Effect of Tongmai Capsules on High-sensitivity C-Reactive Protein in Acute Coronary Syndrome Patients
Abstract: Objective To observe the effect of Tongmai Capsules(TC) on high-sensitivity C-reactive protein(hs-CRP) in acute coronary syndrome(ACS) patients.Methods Fifty-four ACS patients were randomized into the treatment group(N=26) and the control group(N=28).The two groups were given routine treatment for coronary heart disease and the complications.Additionally,the control group was given the placebo,and the treatment group was given TC,the treatment lasting one month.The change of the symptom scores was observed before and after treatment,and the hs-CRP level at the admission day,on the 7th day of treatment and after treatment for one month was also detected.Results(1) The score of symptoms of ACS was improved to various degrees in both groups(P0.05 or P0.01 compared with that before treatment).TC had a better effect on reducing attack frequency,persistence time and the degrees of distress and pain in the chest,and on relieving shortness of breath,lassitude and palpitation(P0.05 or P0.01 compared with the control group).(2) The hs-CRP level had no obvious change in the control group(P0.05) while was decreased in the treatment group(P0.05) on the 7th day of treatment and after treatment for one month as compared with that at the admission day.In the treatment group,hs-CRP level was decreased obviously after treatment for one month(P0.05 compared with that on the 7th day of treatment).On the 7th day of treatment and after treatment for one month,the hs-CRP level in the treatment group differed from that in the control group at the same time(P0.05).Conclusion TC is effective for relieving the symptoms of ACS,and can decrease the hs-CRP level in ACS patients.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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