Title: Expression of EGFR in Tissues of Non-small Cell Lung Cancer in Guangxi
Abstract: Objective To investigate the expression of epidermal growth factor receptor(EGFR)in non-small cell lung cancer(NSCLC)tissue and its relation with clinical pathology and nationality.Methods The expressions of EGFR in 76 lung cancer samples,23 adjacent samples and 8 non-lung cancer samples were detect by real-time PCR.Results The expression of EGFR in lung cancer samples was higher than that in adjacent samples,which was higher than that in non-cancer samples(P0.05).The expression of EGFR had no obvious correlation with pathologic type type,gender,age,nationality and smoking index(P0.05).The expression in the stages Ⅲ-Ⅳ was higher than that in the stagesⅠ-Ⅱ,and that with lymphatic metastasis was higher than that without lymph node metastasis(P0.05).Conclusion There is high EGFR expression in cancer tissue of NSCLC patients in Guangxi,which is related with clinical stages of tumor and lymph node metastasis.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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