Title: Comparison on the effect of Glimepiride and Diamicron in treating type II diabetes
Abstract: To observe the effect and safety of Glimepiride in reducing blood sugar and compare it with Diamicron. 86 cases of type II diabetes were selected, 39 cases of the case group were administrated with GMD (1~4 mg, qd. po); 47 cases of the control group were administrated with Diamicron (40~160 mg, Bid, po). FPG, 2 HPG, HbA 1C,BMI and hypoglycemia of both the two groups were observed, and the clinical effect was evaluated. Both the case group and the control group were found with a decrease of FPG and 2 HPG after administration for 1 week; after administration for 12 weeks, FPG decreased by 2.60 mmol/L in the case group and 2.79 mmol/L in the control group; 2 HPG decreased by 5.45 mmol/L in the case group and 5.19 mmol/L in the control group; HbA 1C also decreased to some extent in both the two groups. The result has statistic significance compared with the standard value. MBI showed no obvious changes, it has no statistic significance. [Conclusion] Both Glimepiride and Diamicron have significant effect in controlling FPG, 2HPG and HbA 1C, the curative effect of them is similar. Both the two groups have hypoglycemia, but it appeared less in the case group.
Publication Year: 2004
Publication Date: 2004-01-01
Language: en
Type: article
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