Title: Clinical Study on the Efficacy of Glimepiride and Metformin in the Treatment of Type 2 Diabetes Mellitus
Abstract: Objective To observe the efficacy of glimepiride combined with metformin in the treatment of type 2 diabetes. Methods A total of 67 patients with type 2 diabetes admitted in Nanyang Institute of Technology Affiliated Hospital from Jun. 2009 to Jul. 2010 were treated with oral administration of glimepiride and metformin for 24 weeks as one course. Levels of FPG,2-hour PBG,HbA1 c before and after treatment and the adverse reactions were monitored and compared. Results Comparing the results after treatment with those before treatment,there were significant decreases in FPG[( 7. 13 ± 1. 75) mmol /L vs( 10. 12 ± 1. 45) mmol /L],PBG[( 9. 47 ± 1. 52) mmol /L vs( 14. 17 ± 2. 33) mmol /L],HbAlc [( 7. 25 ± 1. 37) % vs( 9. 24 ±1. 57) % ]( P 0. 01). Conclusion Glimepiride combined with metformin is safe and effective in controlling the blood glucose level for type 2 diabetes patients with less incidence of hypoglycemia.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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