Title: Serum Cystatin C and Urinary Albumin in Patients with Chronic Glomerulonephritis Early Renal Damage Assessment of the Significance
Abstract: Objective: To investigate serum cystatin C and microalbuminuria in patients with chronic glomerulonephritis early renal damage assessment of significance. Methods: from September 2010 to July 2013 in our hospital, 86 patients with chronic glomerulonephritis, set the observation group. Select another examination in our hospital over the same period by age, sex and other data matched 66 healthy subjects as controls. Respectively, as well as the patient's CysC mALB content were measured, and statistically analysis. Results: The study group and the control group Cys C levels were(2.68±1.19) mg/L,(0.83±1.04) mg/L, the observation group was significantly higher compared with the control group; mALB content of the observation group(38.16±4.25) mg/L, compared to the control group(6.87±3.93) mg/L significantly increased; Cys C and mALB positive indicators detection rate was 75.58%, 76.74%, while the Cys C and mALB joint detection, prosecution the rate was 91.86%, compared to the single index detection rate has improved significantly. Difference was statistically significant(P0.05). Through the two patients with chronic glomerulonephritis indicators correlation analysis found that serum Cys C and urine mALB levels showed a significant positive correlation(r=0.941, P0.05). Conclusions: The combination of CysC with mALB to detect chronic glomerulonephritis patients with early renal damage assessment, the detection rate and sensitivity were significantly higher than the index detection.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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