Title: Effect of rosiglitazone (avandia) on type 2 diabetes mellitus with insulin resistance
Abstract: Objective: To investigate the effect of rosiglitazone on type 2 diabetes mellitus with insulin resistance.
Methods: A total of 160 patients with type 2 diabetes mellitus failed to control with metformin or insulin or sports.
Rosiglitazone of 4 mg per day was given orally based on treatment of metformin and insulin adjusted the dosage
according to level of blood glucose. Levels of fasting blood glucose, 2 hours blood glucose after diet and saccharify
hemoglobin (HbAlc) were monitored before and during the period of Rosiglitazone treatment. Results: The levels of
fasting glucose, 2 hours blood glucose after diet and HbAlc decreased in patients with rosiglitazone treatment, and the
needs of biguanide metformin and insulin decreased at the end of 24 weeks of rosiglitazone treatment. Conclusion:
Rosiglitazone can provide a long-term effect in controlling levels of blood glucose in patients with type 2 diabetes
mellitus with insulin resistance.
Publication Year: 2004
Publication Date: 2004-01-01
Language: en
Type: article
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