Title: Expression and significance of survivin in gastric carcinoma
Abstract: Objective:To study the expression of survivin,an inhibitor of apoptosis protein,in gastric carcinomas and its relation-ship with clinical pathology.Methods:Using immunohistochemical staining method,we examined the expression of survivin in 10 cases of chronic gastritis and 28 cases of gastric carcinomas.Results:Survivin expressed in 20 of 28(71.4%) cases of gastric carcinoma tissues and 1 of 10(10%) cases of chronic gastritis.Over expression of survivin had no relation with age,tumor depth,tumor size,and disease stage,but was significantly related to histological type.Conclusion:These data indicate that survivin plays an important role in the onset of gastric cacinoma.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
Access and Citation
Cited By Count: 4
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot