Title: Antitumor effects of extracellular polysaccharide by Clitocybe gigantean AS 5. 105 on sarcoma 180 in mice
Abstract: An extracellular polysaccharide(CEP) was extracted from submerged fermentation broth of Clitocybe gigantean.With KM mice as animal model,the method of immune organs weight of mice was used.Testing the antitumour effects of extracellular polysaccharide by Clitocybe gigantean AS(5.105) indicated that the polysaccharide CEP could remarkably inhibit the solid Sarcoma 180 in mice.Furthermore,this effect was dosage dependent.Compared with control,high concentration group could significantly increase the thymus and spleen index of mice(P0.05),while compared with low concentration group, high concentration group could significantly increase Spleen index of mice(P0.05).
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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