Publication Information

{'id': 'https://openalex.org/W2351396747', 'doi': None, 'title': '[Protective effects of adiponectin against hypoxia/reoxygenation injury in neonatal rat cardiomyocytes].', 'display_name': '[Protective effects of adiponectin against hypoxia/reoxygenation injury in neonatal rat cardiomyocytes].', 'publication_year': 2010, 'publication_date': '2010-04-25', 'ids': {'openalex': 'https://openalex.org/W2351396747', 'mag': '2351396747', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20401450'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20401450', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5101974795', 'display_name': 'Yunfei Bian', 'orcid': 'https://orcid.org/0000-0002-2699-0749'}, 'institutions': [{'id': 'https://openalex.org/I4210133678', 'display_name': 'Second Hospital of Shanxi Medical University', 'ror': 'https://ror.org/03tn5kh37', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210133678']}, {'id': 'https://openalex.org/I17721919', 'display_name': 'Shanxi Medical University', 'ror': 'https://ror.org/0265d1010', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I17721919']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yun-Fei Bian', 'raw_affiliation_strings': ['Department of Cardiology, the Second Affiliated Hospital of Shanxi Medical University, Taiyuan 030001, China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, the Second Affiliated Hospital of Shanxi Medical University, Taiyuan 030001, China.', 'institution_ids': ['https://openalex.org/I4210133678', 'https://openalex.org/I17721919']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103052016', 'display_name': 'Xiaoxia Guo', 'orcid': 'https://orcid.org/0000-0002-8381-3781'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Xiao-Xia Guo', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5051212432', 'display_name': 'Xiao Chuan-shi', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Chuan-Shi Xiao', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.375, 'has_fulltext': False, 'cited_by_count': 3, 'citation_normalized_percentile': {'value': 0.587048, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 75, 'max': 77}, 'biblio': {'volume': '62', 'issue': '2', 'first_page': '149', 'last_page': '55'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11457', 'display_name': 'Adipose Tissue and Metabolism', 'score': 0.9687, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11457', 'display_name': 'Adipose Tissue and Metabolism', 'score': 0.9687, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10528', 'display_name': 'Adipokines, Inflammation, and Metabolic Diseases', 'score': 0.9426, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12979', 'display_name': 'Cardiovascular Disease and Adiposity', 'score': 0.9131, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/agarose-gel-electrophoresis', 'display_name': 'Agarose gel electrophoresis', 'score': 0.59508014}, {'id': 'https://openalex.org/keywords/hypoxia', 'display_name': 'Hypoxia', 'score': 0.45506}], 'concepts': [{'id': 'https://openalex.org/C2780124434', 'wikidata': 'https://www.wikidata.org/wiki/Q12357464', 'display_name': 'AMPK', 'level': 4, 'score': 0.70819044}, {'id': 'https://openalex.org/C2778271344', 'wikidata': 'https://www.wikidata.org/wiki/Q903395', 'display_name': 'Agarose gel electrophoresis', 'level': 3, 'score': 0.59508014}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.5737488}, {'id': 'https://openalex.org/C2776782570', 'wikidata': 'https://www.wikidata.org/wiki/Q357439', 'display_name': 'Adiponectin', 'level': 4, 'score': 0.5726383}, {'id': 'https://openalex.org/C2775838275', 'wikidata': 'https://www.wikidata.org/wiki/Q410776', 'display_name': 'Superoxide dismutase', 'level': 3, 'score': 0.54596806}, {'id': 'https://openalex.org/C2776151105', 'wikidata': 'https://www.wikidata.org/wiki/Q898814', 'display_name': 'Oxidative stress', 'level': 2, 'score': 0.5201567}, {'id': 'https://openalex.org/C11960822', 'wikidata': 'https://www.wikidata.org/wiki/Q242736', 'display_name': 'Phosphorylation', 'level': 2, 'score': 0.4676024}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.46731752}, {'id': 'https://openalex.org/C7836513', 'wikidata': 'https://www.wikidata.org/wiki/Q1641506', 'display_name': 'Hypoxia (environmental)', 'level': 3, 'score': 0.45506}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.451348}, {'id': 'https://openalex.org/C553184892', 'wikidata': 'https://www.wikidata.org/wiki/Q1141429', 'display_name': 'Flow cytometry', 'level': 2, 'score': 0.4484029}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.44776732}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.4412676}, {'id': 'https://openalex.org/C57600042', 'wikidata': 'https://www.wikidata.org/wiki/Q227564', 'display_name': 'Oxidative phosphorylation', 'level': 2, 'score': 0.426532}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.37869197}, {'id': 'https://openalex.org/C16685009', 'wikidata': 'https://www.wikidata.org/wiki/Q335057', 'display_name': 'Andrology', 'level': 1, 'score': 0.3386457}, {'id': 'https://openalex.org/C97029542', 'wikidata': 'https://www.wikidata.org/wiki/Q281417', 'display_name': 'Protein kinase A', 'level': 3, 'score': 0.22874013}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.2034181}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.12212092}, {'id': 'https://openalex.org/C540031477', 'wikidata': 'https://www.wikidata.org/wiki/Q629', 'display_name': 'Oxygen', 'level': 2, 'score': 0.08469415}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.072576165}, {'id': 'https://openalex.org/C2779306644', 'wikidata': 'https://www.wikidata.org/wiki/Q2002370', 'display_name': 'Insulin', 'level': 2, 'score': 0.06902745}, {'id': 'https://openalex.org/C2777391703', 'wikidata': 'https://www.wikidata.org/wiki/Q1053470', 'display_name': 'Insulin resistance', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D052242', 'descriptor_name': 'Adiponectin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D015428', 'descriptor_name': 'Myocardial Reperfusion Injury', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': True}, {'descriptor_ui': 'D032383', 'descriptor_name': 'Myocytes, Cardiac', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': True}, {'descriptor_ui': 'D055372', 'descriptor_name': 'AMP-Activated Protein Kinases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055372', 'descriptor_name': 'AMP-Activated Protein Kinases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D052242', 'descriptor_name': 'Adiponectin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000831', 'descriptor_name': 'Animals, Newborn', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002316', 'descriptor_name': 'Cardiotonic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002316', 'descriptor_name': 'Cardiotonic Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D015687', 'descriptor_name': 'Cell Hypoxia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015428', 'descriptor_name': 'Myocardial Reperfusion Injury', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D032383', 'descriptor_name': 'Myocytes, Cardiac', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018384', 'descriptor_name': 'Oxidative Stress', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017207', 'descriptor_name': 'Rats, Sprague-Dawley', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20401450', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.68, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3138846345', 'https://openalex.org/W3091935260', 'https://openalex.org/W3031066848', 'https://openalex.org/W3030044904', 'https://openalex.org/W3028720090', 'https://openalex.org/W2998513787', 'https://openalex.org/W2992714606', 'https://openalex.org/W2556901529', 'https://openalex.org/W2491740661', 'https://openalex.org/W2463239974', 'https://openalex.org/W2373237698', 'https://openalex.org/W2372911669', 'https://openalex.org/W2372462701', 'https://openalex.org/W2364957310', 'https://openalex.org/W2358698904', 'https://openalex.org/W2351728424', 'https://openalex.org/W2351687065', 'https://openalex.org/W2349476379', 'https://openalex.org/W193572013', 'https://openalex.org/W1597963938'], 'abstract_inverted_index': {'The': [0, 68, 79], 'aim': [1], 'of': [2, 11, 121, 134, 160, 183, 189], 'the': [3, 9, 89, 98, 106, 112, 118, 132, 167, 176, 180, 187], 'present': [4], 'study': [5], 'is': [6], 'to': [7], 'investigate': [8], 'effects': [10], 'adiponectin': [12, 195], '(APN)': [13], 'on': [14], 'hypoxia/reoxygenation': [15], '(H/R)': [16], 'injury': [17], 'in': [18, 45, 102, 111, 166, 172], 'cultured': [19, 39], 'cardiomyocytes.': [20], 'Primary': [21, 37], 'cardiomyocytes': [22, 198], 'were': [23, 43, 74, 114, 170], 'obtained': [24], 'from': [25, 199], 'neonatal': [26], 'rats': [27], 'by': [28, 34, 84, 94, 126, 138], 'enzymatic': [29], 'digestion': [30], 'method': [31], 'and': [32, 47, 65, 71, 88, 105, 131, 157, 185, 203], 'identified': [33], 'immunofluorescent': [35], 'technique.': [36], 'cells': [38, 104], 'for': [40], '72': [41], 'h': [42], 'used': [44], 'experiment': [46], 'divided': [48], 'into': [49], '5': [50], 'groups': [51], 'randomly:': [52], 'Control': [53], 'group,': [54, 56, 58, 64, 144], 'H/R': [55, 145], 'H/R+APN': [57, 173], 'H/R+APN+adenine': [59], '9-beta-D-arabinfuranoside': [60], '(AraA,': [61], 'AMPK': [62, 135, 161, 206], 'inhibitor)': [63], 'H/R+AraA': [66], 'group.': [67, 174], 'cardiocyte': [69], 'morphology': [70], 'beating': [72], 'rate': [73], 'observed': [75, 125], 'under': [76], 'inverted': [77], 'microscope.': [78], 'DNA': [80], 'ladder': [81], 'was': [82, 92, 124, 136], 'examined': [83], 'agarose': [85], 'gel': [86], 'electrophoresis,': [87], 'cell': [90], 'apoptosis': [91, 204], 'determined': [93, 137], 'flow': [95], 'cytometry.': [96], 'Moreover,': [97], 'malondialchehyche': [99], '(MDA)': [100], 'content': [101], 'myocardial': [103], 'superoxide': [107], 'dismutase': [108], '(SOD)': [109], 'activity': [110], 'supernatant': [113], 'measured': [115], 'using': [116], 'kits,': [117], 'fluorescence': [119], 'intensity': [120], 'intracellular': [122, 154], 'Ca2+': [123, 155], 'laser': [127], 'scanning': [128], 'confocal': [129], 'microscope,': [130], 'phosphorylation': [133, 158, 188], 'Western': [139], 'blotting.': [140], 'Compared': [141], 'with': [142], 'control': [143], 'group': [146], 'showed': [147], 'increased': [148], 'apoptotic': [149], 'rate,': [150], 'oxidative': [151, 201], 'stress': [152, 202], 'level,': [153], 'concentration': [156], 'level': [159], '(P<0.05),': [162], 'while': [163], 'significant': [164], 'ameliorations': [165], 'above': [168], 'indices': [169], 'seen': [171], 'On': [175], 'contrast,': [177], 'AraA': [178], 'attenuated': [179], 'protective': [181], 'effect': [182], 'APN': [184], 'decreased': [186], 'AMPK.': [190], 'These': [191], 'results': [192], 'suggest': [193], 'that': [194], 'can': [196], 'protect': [197], 'H/R-induced': [200], 'through': [205], 'pathway.': [207]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2351396747', 'counts_by_year': [{'year': 2015, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-24T12:39:31.035577', 'created_date': '2016-06-24'}