Title: Relationship of microvessel density changes with its pathological characteristics and prognosis
Abstract: Objective To study the relationship of microvessel density(MVD) changes in gallbladder carcinoma and its pathological charactors and prognosis.Methods The MVD in 42 cases with gallbladder carcinoma tissues were studied by immunohistochemistry avidin-biotin-complex method and image analysis.Results The average data of MVD in gallbladder carcinoma tissues was 70.4±20.7.That of highand middle defferentition groups were 57.9±15.4,That of lowanl no defferentition groups were 88.8±11.5(P0.01).That of no invasion inserosa groups were 53.3±14.4,That of invasion inserosa groups were 72.7±17.0(P0.05).That of no lymph node metastasis groups were 54.6±13.0,That of lymph node metastasis groups were 76.0±15.6(P0.01).The three years survival rate of average date of MVD71.5 groups were 9.5%,That of average date of MVD71.5 groups were 66.6%(P0.01).The gallbladder carcinoma MVD and tumor growth method and histology mode had no statistics meaning(P0.05).Conclusion Mroe MVD may promote cancer cell invasing and transfering.MVD may be regarded as an important index of pathological biological behavior and prognosis of gallbladder carcinoma.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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