Publication Information

{'id': 'https://openalex.org/W2116936462', 'doi': 'https://doi.org/10.1002/path.2390', 'title': 'Discovery of myopodin methylation in bladder cancer', 'display_name': 'Discovery of myopodin methylation in bladder cancer', 'publication_year': 2008, 'publication_date': '2008-06-13', 'ids': {'openalex': 'https://openalex.org/W2116936462', 'doi': 'https://doi.org/10.1002/path.2390', 'mag': '2116936462', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/18636402'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/path.2390', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4394736614', 'display_name': 'The Journal of Pathology', 'issn_l': '0022-3417', 'issn': ['0022-3417', '1096-9896'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5076694130', 'display_name': 'Virginia Cebrián', 'orcid': 'https://orcid.org/0000-0002-3414-4796'}, 'institutions': [{'id': 'https://openalex.org/I4210089594', 'display_name': 'Spanish National Cancer Research Centre', 'ror': 'https://ror.org/00bvhmc43', 'country_code': 'ES', 'type': 'facility', 'lineage': ['https://openalex.org/I4210089594']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'V Cebrian', 'raw_affiliation_strings': ['Tumor Markers Group, Molecular Pathology Program, Spanish National Cancer Center, Madrid, Spain.'], 'affiliations': [{'raw_affiliation_string': 'Tumor Markers Group, Molecular Pathology Program, Spanish National Cancer Center, Madrid, Spain.', 'institution_ids': ['https://openalex.org/I4210089594']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040017671', 'display_name': 'Victoria Álvarez', 'orcid': 'https://orcid.org/0000-0002-1916-2523'}, 'institutions': [{'id': 'https://openalex.org/I4210133994', 'display_name': 'Central University Hospital of Asturias', 'ror': 'https://ror.org/03v85ar63', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210133994']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'M Alvarez', 'raw_affiliation_strings': ['Urology Department, Hospital Central de Asturias, Oviedo, Spain'], 'affiliations': [{'raw_affiliation_string': 'Urology Department, Hospital Central de Asturias, Oviedo, Spain', 'institution_ids': ['https://openalex.org/I4210133994']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027993087', 'display_name': 'A. Aleman', 'orcid': 'https://orcid.org/0000-0002-3679-8451'}, 'institutions': [{'id': 'https://openalex.org/I4210089594', 'display_name': 'Spanish National Cancer Research Centre', 'ror': 'https://ror.org/00bvhmc43', 'country_code': 'ES', 'type': 'facility', 'lineage': ['https://openalex.org/I4210089594']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'A Aleman', 'raw_affiliation_strings': ['Tumor Markers Group, Molecular Pathology Program, Spanish National Cancer Center, Madrid, Spain.'], 'affiliations': [{'raw_affiliation_string': 'Tumor Markers Group, Molecular Pathology Program, Spanish National Cancer Center, Madrid, Spain.', 'institution_ids': ['https://openalex.org/I4210089594']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5033224206', 'display_name': 'Joan Palou', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210143013', 'display_name': 'Puigvert Foundation', 'ror': 'https://ror.org/03qwx2883', 'country_code': 'ES', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210143013']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'J Palou', 'raw_affiliation_strings': ['Urology Department, Fundació Puigvert, Barcelona, Spain'], 'affiliations': [{'raw_affiliation_string': 'Urology Department, Fundació Puigvert, Barcelona, Spain', 'institution_ids': ['https://openalex.org/I4210143013']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074756323', 'display_name': 'Joaquim Bellmunt', 'orcid': 'https://orcid.org/0000-0003-2328-3421'}, 'institutions': [{'id': 'https://openalex.org/I4210130874', 'display_name': 'Hospital Del Mar', 'ror': 'https://ror.org/03a8gac78', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210130874']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'J Bellmunt', 'raw_affiliation_strings': ['Oncology Department, Hospital del Mar, Barcelona, Spain'], 'affiliations': [{'raw_affiliation_string': 'Oncology Department, Hospital del Mar, Barcelona, Spain', 'institution_ids': ['https://openalex.org/I4210130874']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113829216', 'display_name': 'Pilar González‐Peramato', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210093872', 'display_name': 'Hospital Universitario de Guadalajara', 'ror': 'https://ror.org/00jkz9152', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210093872', 'https://openalex.org/I4210141158']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'P Gonzalez‐Peramato', 'raw_affiliation_strings': ['Pathology Department, Hospital de Guadalajara, Guadalajara, Spain'], 'affiliations': [{'raw_affiliation_string': 'Pathology Department, Hospital de Guadalajara, Guadalajara, Spain', 'institution_ids': ['https://openalex.org/I4210093872']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080940311', 'display_name': 'Carlos Cordon‐Cardo', 'orcid': 'https://orcid.org/0000-0003-0858-5624'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'C Cordón‐Cardo', 'raw_affiliation_strings': ['Pathology Department, Memorial Sloan‐Kettering Cancer Center (MSKCC), New York, USA'], 'affiliations': [{'raw_affiliation_string': 'Pathology Department, Memorial Sloan‐Kettering Cancer Center (MSKCC), New York, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052118412', 'display_name': 'Javier Garcı́a Garcı́a', 'orcid': 'https://orcid.org/0000-0002-2986-7228'}, 'institutions': [{'id': 'https://openalex.org/I4210099034', 'display_name': 'Complejo Hospitalario de Salamanca', 'ror': 'https://ror.org/0131vfw26', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I184999862', 'https://openalex.org/I4210099034']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'J García', 'raw_affiliation_strings': ['Urology Department, Hospital Universitario de Salamanca, Salamanca, Spain'], 'affiliations': [{'raw_affiliation_string': 'Urology Department, Hospital Universitario de Salamanca, Salamanca, Spain', 'institution_ids': ['https://openalex.org/I4210099034']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019869973', 'display_name': 'Josep M. Piulats', 'orcid': 'https://orcid.org/0000-0002-3606-1724'}, 'institutions': [{'id': 'https://openalex.org/I4210107147', 'display_name': "Institut Català d'Oncologia", 'ror': 'https://ror.org/01j1eb875', 'country_code': 'ES', 'type': 'government', 'lineage': ['https://openalex.org/I4210107147']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'JM Piulats', 'raw_affiliation_strings': ["Oncology Department, Institut Catalá d'Oncologia, Barcelona, Spain"], 'affiliations': [{'raw_affiliation_string': "Oncology Department, Institut Catalá d'Oncologia, Barcelona, Spain", 'institution_ids': ['https://openalex.org/I4210107147']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5052620864', 'display_name': 'Marta Sänchez‐Carbayo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210089594', 'display_name': 'Spanish National Cancer Research Centre', 'ror': 'https://ror.org/00bvhmc43', 'country_code': 'ES', 'type': 'facility', 'lineage': ['https://openalex.org/I4210089594']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'M Sánchez‐Carbayo', 'raw_affiliation_strings': ['Tumor Markers Group, Molecular Pathology Program, Spanish National Cancer Center, Madrid, Spain.'], 'affiliations': [{'raw_affiliation_string': 'Tumor Markers Group, Molecular Pathology Program, Spanish National Cancer Center, Madrid, Spain.', 'institution_ids': ['https://openalex.org/I4210089594']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 8, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.788, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 29, 'citation_normalized_percentile': {'value': 0.756214, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '216', 'issue': '1', 'first_page': '111', 'last_page': '119'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetics and DNA Methylation', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetics and DNA Methylation', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10458', 'display_name': 'Bladder and Urothelial Cancer Treatments', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12695', 'display_name': 'Urinary and Genital Oncology Studies', 'score': 0.938, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/demethylating-agent', 'display_name': 'Demethylating agent', 'score': 0.70573354}, {'id': 'https://openalex.org/keywords/cpg-site', 'display_name': 'CpG site', 'score': 0.54537886}], 'concepts': [{'id': 'https://openalex.org/C33288867', 'wikidata': 'https://www.wikidata.org/wiki/Q518328', 'display_name': 'Methylation', 'level': 3, 'score': 0.8846483}, {'id': 'https://openalex.org/C2780352672', 'wikidata': 'https://www.wikidata.org/wiki/Q504775', 'display_name': 'Bladder cancer', 'level': 3, 'score': 0.7371609}, {'id': 'https://openalex.org/C190727270', 'wikidata': 'https://www.wikidata.org/wiki/Q874745', 'display_name': 'DNA methylation', 'level': 4, 'score': 0.70655084}, {'id': 'https://openalex.org/C2779277951', 'wikidata': 'https://www.wikidata.org/wiki/Q5255196', 'display_name': 'Demethylating agent', 'level': 5, 'score': 0.70573354}, {'id': 'https://openalex.org/C41091548', 'wikidata': 'https://www.wikidata.org/wiki/Q26939', 'display_name': 'Epigenetics', 'level': 3, 'score': 0.5502956}, {'id': 'https://openalex.org/C140173407', 'wikidata': 'https://www.wikidata.org/wiki/Q1138358', 'display_name': 'CpG site', 'level': 5, 'score': 0.54537886}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.53135186}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5046803}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.49120945}, {'id': 'https://openalex.org/C119056186', 'wikidata': 'https://www.wikidata.org/wiki/Q1431332', 'display_name': 'Gene silencing', 'level': 3, 'score': 0.45942616}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.3771949}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.35129458}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.2941641}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.2473062}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.102289766}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.078893125}], 'mesh': [{'descriptor_ui': 'D018899', 'descriptor_name': 'CpG Islands', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D008840', 'descriptor_name': 'Microfilament Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D001749', 'descriptor_name': 'Urinary Bladder Neoplasms', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': True}, {'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D018899', 'descriptor_name': 'CpG Islands', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008745', 'descriptor_name': 'Methylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008840', 'descriptor_name': 'Microfilament Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008840', 'descriptor_name': 'Microfilament Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016133', 'descriptor_name': 'Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D046888', 'descriptor_name': 'Tissue Array Analysis', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D046888', 'descriptor_name': 'Tissue Array Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001749', 'descriptor_name': 'Urinary Bladder Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001749', 'descriptor_name': 'Urinary Bladder Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001749', 'descriptor_name': 'Urinary Bladder Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/path.2390', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4394736614', 'display_name': 'The Journal of Pathology', 'issn_l': '0022-3417', 'issn': ['0022-3417', '1096-9896'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/18636402', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.7, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 28, 'referenced_works': ['https://openalex.org/W1498617603', 'https://openalex.org/W1504303645', 'https://openalex.org/W1975377403', 'https://openalex.org/W1976770439', 'https://openalex.org/W1999628666', 'https://openalex.org/W2005214485', 'https://openalex.org/W2016787034', 'https://openalex.org/W2029484950', 'https://openalex.org/W2036986058', 'https://openalex.org/W2040257851', 'https://openalex.org/W2045614922', 'https://openalex.org/W2046509449', 'https://openalex.org/W2047708528', 'https://openalex.org/W2050428093', 'https://openalex.org/W2054169897', 'https://openalex.org/W2062360063', 'https://openalex.org/W2098645857', 'https://openalex.org/W2100248081', 'https://openalex.org/W2117490187', 'https://openalex.org/W2129430629', 'https://openalex.org/W2132864654', 'https://openalex.org/W2135025419', 'https://openalex.org/W2141870702', 'https://openalex.org/W2142570413', 'https://openalex.org/W2147955588', 'https://openalex.org/W2154590990', 'https://openalex.org/W2157634892', 'https://openalex.org/W2275614507'], 'related_works': ['https://openalex.org/W4200236841', 'https://openalex.org/W3152305951', 'https://openalex.org/W3029570287', 'https://openalex.org/W2944524138', 'https://openalex.org/W2588553988', 'https://openalex.org/W2582088144', 'https://openalex.org/W2380976670', 'https://openalex.org/W2364944693', 'https://openalex.org/W2169344098', 'https://openalex.org/W2123238153'], 'abstract_inverted_index': {'Myopodin': [0, 57, 88, 104, 117], 'is': [1], 'an': [2, 15], 'actin-binding': [3], 'protein': [4], 'that': [5], 'shuttles': [6], 'between': [7], 'the': [8, 11, 20, 29, 227, 235], 'nucleus': [9], 'and': [10, 53, 113, 182, 204, 211], 'cytoplasm.': [12], 'After': [13], 'identifying': [14], 'enriched': [16], 'CpG': [17], 'island': [18], 'encompassing': [19], 'transcription': [21], 'site': [22], 'of': [23, 32, 41, 75, 99, 139, 176, 180, 186, 201, 229, 238], 'myopodin,': [24], 'we': [25], 'aimed': [26], 'at': [27], 'evaluating': [28], 'potential': [30], 'relevance': [31], 'myopodin': [33, 42, 76, 132, 142, 151, 160, 189, 202, 231], 'methylation': [34, 73, 105, 133, 152, 161, 203, 232], 'in': [35, 47, 66, 95, 162, 196, 234], 'bladder': [36, 48, 101, 128, 169, 197, 220], 'cancer.': [37, 198], 'The': [38, 72, 137, 199], 'epigenetic': [39], 'silencing': [40], 'by': [43, 68, 81, 122, 241], 'hypermethylation': [44, 58], 'was': [45, 59, 78, 89, 106, 134, 154, 190], 'tested': [46], 'cancer': [49, 170, 209, 221], 'cells': [50], '(n=12)': [51], 'before': [52], 'after': [54], 'azacytidine': [55], 'treatment.': [56], 'associated': [60, 108, 155], 'with': [61, 109, 150, 156, 168, 173, 208, 215], 'gene': [62], 'expression,': [63], 'being': [64], 'increased': [65], 'vitro': [67], 'this': [69], 'demethylating': [70], 'agent.': [71], 'status': [74], 'promoter': [77], 'then': [79], 'evaluated': [80], 'methylation-specific': [82], 'polymerase': [83], 'chain': [84], 'reaction': [85], '(MS-PCR)': [86], 'analyses.': [87], 'revealed': [90], 'to': [91, 192, 218], 'be': [92, 193], 'frequently': [93], 'methylated': [94], 'a': [96, 174, 178, 183], 'large': [97], 'series': [98], '466': [100], 'tumours': [102, 129], '(68.7%).': [103], 'significantly': [107], 'tumour': [110, 114], 'stage': [111], '(p<0.0005)': [112], 'grade': [115], '(p=0.037).': [116], 'expression': [118, 143, 206], 'patterns': [119, 207], 'were': [120], 'analysed': [121], 'immunohistochemistry': [123], 'on': [124], 'tissue': [125], 'arrays': [126], 'containing': [127], 'for': [130], 'which': [131], 'assessed': [135], '(n=177).': [136], 'presence': [138], 'low': [140], 'nuclear': [141, 205], 'alone': [144], '(p': [145], '=': [146], '0.031)': [147], 'or': [148], 'combined': [149], '(p=0.008)': [153], 'poor': [157], 'survival.': [158], 'Moreover,': [159], '164': [163], 'urinary': [164, 224], 'specimens': [165], 'distinguished': [166], 'patients': [167, 222, 239], 'from': [171], 'controls': [172], 'sensitivity': [175], '65.0%,': [177], 'specificity': [179], '79.8%,': [181], 'global': [184], 'accuracy': [185], '75.3%.': [187], 'Thus,': [188], 'identified': [191], 'epigenetically': [194], 'modified': [195], 'association': [200], 'progression': [210], 'clinical': [212, 236], 'outcome,': [213], 'together': [214], 'its': [216], 'ability': [217], 'detect': [219], 'using': [223], 'specimens,': [225], 'suggests': [226], 'utility': [228], 'incorporating': [230], 'assessment': [233], 'management': [237], 'affected': [240], 'uroepithelial': [242], 'neoplasias.': [243]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2116936462', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 8}], 'updated_date': '2025-01-12T19:40:27.141060', 'created_date': '2016-06-24'}