Publication Year: 2020
DOI: https://doi.org/10.1158/1538-7445.am2020-ct014
Abstract: Abstract Background: antagonist enza alone in pts with mCRPC who had progressed on enzalutamide abiraterone and docetaxel, or were not candidates for a taxane (enza). regimen (androgen deprivation therapy was not given). Eligible pts had Enza mCRPC or locally advanced, incurable CRPC, ECOG PS 0/1 and may no prior immunotherapy Show more
Authors:
Publication Year: 2020
DOI: https://doi.org/10.1097/ju.0000000000000859.012
Abstract: You have II Feyerabend , Neal ShoreNeal Shore , Gwenaelle GravisGwenaelle Gravis , (PD16)1 Brigitte LaguerreBrigitte Laguerre , Howard GurneyHoward Gurney , Margitta RetzMargitta Apr Retz , Emanuela RomanoEmanuela Romano , Loic MoureyLoic Mourey , 2020PD16-12 Johann S. de BonoJohann S. de Bono , Audrey KamAudrey PEMBROLIZUMAB Kam , Urban Show more
Authors:
Publication Year: 2016
DOI: https://doi.org/10.1002/cncr.30258
Abstract: Antibodies inhibiting significant eligible patients, 48 (86%) had received prior therapy, and 35 activity (63%) had received treatment with ipilimumab. Three patients had an in objective response to ipilimumab, and 8 had stable disease as the their best response. Thirty-eight patients (68%) received pembrolizumab, 16 (29%) treatment received nivolumab, and Show more
Authors:
Publication Year: 2021
DOI: https://doi.org/10.1097/ju.0000000000002015.14
Abstract: You have II Nordquist More articles by this author , Evan Y. YuEvan (MP24)1 Y. Yu More articles by this author , Josep M. Sep PiulatsJosep M. Piulats More articles by this author , Gwenaelle 2021MP24-14 GravisGwenaelle Gravis More articles by this author , Peter C.C. PEMBROLIZUMAB FongPeter C.C. Fong Show more
Authors:
Publication Year: 2024
DOI: https://doi.org/10.1158/1538-7445.am2024-ct018
Abstract: Abstract Background: repair had non-HRR gene muts with/without HRR gene muts; 98 (16%) (HRR) pts had TMPRSS2-ERG fusions. In these 616 pts, TALA + gene ENZA improved rPFS vs PBO + ENZA (Table). TALA + mutations ENZA improved rPFS in pts with TMPRSS2-ERG, RB1, or MLL2 (muts) muts, and objective Show more
Authors:
Publication Year: 2011
DOI: https://doi.org/10.1200/jco.2011.37.8828
Abstract: Not available
Authors:
Publication Year: 2021
DOI: https://doi.org/10.1007/s13555-021-00598-6
Abstract: Pembrolizumab provided metastatic global health status (GHS)/QoL, functioning, symptom and European Quality of (R/M) Life 5-Dimension 5-Level (EQ-5D-5L) scores and change from baseline through cutaneous week 48 in EORTC QLQ-C30 GHS/QoL and physical functioning scores. squamous Improvement (≥ 10-point increase post-baseline with confirmation) was assessed using cell the exact binomial Show more
Authors:
Publication Year: 2020
DOI: https://doi.org/10.1101/2020.04.27.063214
Abstract: Abstract Merkel tumor tumor genome. Our method has been validated in a set of of MCC samples previously characterized in the laboratory as MCV+ the or MCV-, achieving 100% sensitivity and 62,5% specificity. Thus, with skin enough depth of sequencing, it is possible to use WES in to the presence Show more
Authors:
Publication Year: 2023
DOI: https://doi.org/10.1158/1538-7445.am2023-ct223
Abstract: Abstract Background: approved 3+. Primary objective was overall response rate and secondary objectives for included safety and OS. OS was estimated by Kaplan-Meier method. adult Survival for ctDNA evaluable patients was assessed. Analyses are based HLA-A*02:01+ on a 17 Oct 2022 database lock. Results: With a patients median follow-up of Show more
Authors:
Publication Year: 2024
DOI: https://doi.org/10.1158/1538-7445.am2024-ct231
Abstract: Abstract Background: (rPFS) Oncology Biomarker Panel (with 10 additional genes implicated in PARP regardless inhibitor sensitivity; n=304). Correlations between baseline molecular biomarkers and rPFS of were assessed via a Cox proportional hazards model. Multivariate elastic homologous net regression analysis incorporated 151 pts in the TALA + recombination ENZA arm with Show more
Authors:
Publication Year: 2023
DOI: https://doi.org/10.1136/jitc-2023-sitc2023.0895
Abstract: Background
Emerging increased AR-V7 levels were downregulated using specific siRNA. Myc-CaP cells were programmed chronically exposed to increasing concentrations of enzalutamide (5–50 μM) for death-ligand >12 months, and the cells resistant to enzalutamide were referred 1 to as Myc-CaP MDVR. The gene-regulating mechanisms in drug-resistant prostate (PD-L1) cancer cells were Show more
Authors:
Publication Year: 2023
DOI: https://doi.org/10.3389/fonc.2023.1161759
Abstract: In recent of online platform through the construction and visualization of bibliometric networks, tumor the country/region, institution, journal, author, and keywords were analyzed to immune predict the most recent trends in research pertaining to ocular suppression melanoma and immunotherapy.A total of 401 papers and 144 reviews be related to immunotherapy Show more
Authors:
Publication Year: 2020
DOI: https://doi.org/10.1136/ijgc-2020-esgo.110
Abstract: Introduction/Background
PARP (CT) models were adjusted by BRCA status and Pt-free interval (PFI) significantly (6–12 months(mo) vs ≥12 mo). Adjusted hazard ratios (aHR) and improves odds ratios (aOR) of the risk of progression/death and ORR, progression-free respectively, were reported with 95% confidence intervals (CI). Results
56p survival were identified (32p Show more
Authors:
Publication Year: 2016
DOI: https://doi.org/10.1002/cncr.30398
Abstract: This news public policy analysis, topical issues, and personalities.This edition looks at section the results of a study pointing to an international rise offers in rates of thyroid cancer overdiagnosis, how adherence to cancer Cancer prevention guidelines may reduce rates of all cancers by 10% readers to 40%, and how Show more
Authors:
Publication Year: 2018
DOI: https://doi.org/10.17583/brac.2018.2158
Abstract: In the Antoni the transcendental message this creatorleft us. In the last stage Tàpies of his life he emphasized between the nexus of art (06/02/2012)I andspirituality, as well as the urgency of finding equivalents of followed traditionalcontemplative spiritual experiences, adapted to the modern mind. a trail of movements in an Show more
Authors:
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