Publication Information

{'id': 'https://openalex.org/W2019969911', 'doi': 'https://doi.org/10.4161/cc.3.5.820', 'title': 'Resisting Arrest: Recovery from Checkpoint Arrest Through Dephosphorylation of Chk1 by PP1', 'display_name': 'Resisting Arrest: Recovery from Checkpoint Arrest Through Dephosphorylation of Chk1 by PP1', 'publication_year': 2004, 'publication_date': '2004-05-01', 'ids': {'openalex': 'https://openalex.org/W2019969911', 'doi': 'https://doi.org/10.4161/cc.3.5.820', 'mag': '2019969911', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15020842'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.4161/cc.3.5.820', 'pdf_url': 'https://www.tandfonline.com/doi/pdf/10.4161/cc.3.5.820?needAccess=true', 'source': {'id': 'https://openalex.org/S86011449', 'display_name': 'Cell Cycle', 'issn_l': '1551-4005', 'issn': ['1551-4005', '1538-4101'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.tandfonline.com/doi/pdf/10.4161/cc.3.5.820?needAccess=true', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5018677801', 'display_name': 'Nicole den Elzen', 'orcid': 'https://orcid.org/0000-0003-0223-4954'}, 'institutions': [{'id': 'https://openalex.org/I165143802', 'display_name': 'University of Queensland', 'ror': 'https://ror.org/00rqy9422', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I165143802']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Nicole den Elzen', 'raw_affiliation_strings': ['Institute for Molecular Bioscience, Queensland Bioscience Precinct, University of Queensland, St. Lucia, Australia'], 'affiliations': [{'raw_affiliation_string': 'Institute for Molecular Bioscience, Queensland Bioscience Precinct, University of Queensland, St. Lucia, Australia', 'institution_ids': ['https://openalex.org/I165143802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012157236', 'display_name': 'Ana Kosoy', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Ana Kosoy', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090226296', 'display_name': 'Helen Christopoulos', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Helen Christopoulos', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5013107841', 'display_name': 'Matthew J. O’Connell', 'orcid': 'https://orcid.org/0000-0002-0061-2504'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Matthew J. O’Connell', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.307, 'has_fulltext': False, 'cited_by_count': 25, 'citation_normalized_percentile': {'value': 0.660272, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 88, 'max': 89}, 'biblio': {'volume': '3', 'issue': '5', 'first_page': '527', 'last_page': '531'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10123', 'display_name': 'DNA Repair Mechanisms', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10123', 'display_name': 'DNA Repair Mechanisms', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10492', 'display_name': 'Microtubule and mitosis dynamics', 'score': 0.9969, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10301', 'display_name': 'Mitochondrial Function and Pathology', 'score': 0.9913, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/chek1', 'display_name': 'CHEK1', 'score': 0.8737756}, {'id': 'https://openalex.org/keywords/checkpoint-kinase-2', 'display_name': 'Checkpoint Kinase 2', 'score': 0.58845085}, {'id': 'https://openalex.org/keywords/spindle-checkpoint', 'display_name': 'Spindle checkpoint', 'score': 0.46335605}], 'concepts': [{'id': 'https://openalex.org/C54086632', 'wikidata': 'https://www.wikidata.org/wiki/Q5512671', 'display_name': 'G2-M DNA damage checkpoint', 'level': 5, 'score': 0.96081734}, {'id': 'https://openalex.org/C50001416', 'wikidata': 'https://www.wikidata.org/wiki/Q17861750', 'display_name': 'CHEK1', 'level': 5, 'score': 0.8737756}, {'id': 'https://openalex.org/C105696609', 'wikidata': 'https://www.wikidata.org/wiki/Q1068809', 'display_name': 'Cell cycle checkpoint', 'level': 4, 'score': 0.7728417}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.6907036}, {'id': 'https://openalex.org/C143425029', 'wikidata': 'https://www.wikidata.org/wiki/Q5205747', 'display_name': 'DNA damage', 'level': 3, 'score': 0.6804829}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.6214931}, {'id': 'https://openalex.org/C2910325170', 'wikidata': 'https://www.wikidata.org/wiki/Q14912280', 'display_name': 'Checkpoint Kinase 2', 'level': 5, 'score': 0.58845085}, {'id': 'https://openalex.org/C2779429346', 'wikidata': 'https://www.wikidata.org/wiki/Q2236682', 'display_name': 'Schizosaccharomyces pombe', 'level': 4, 'score': 0.50911015}, {'id': 'https://openalex.org/C175732170', 'wikidata': 'https://www.wikidata.org/wiki/Q9064829', 'display_name': 'Spindle checkpoint', 'level': 5, 'score': 0.46335605}, {'id': 'https://openalex.org/C134935766', 'wikidata': 'https://www.wikidata.org/wiki/Q210538', 'display_name': 'DNA repair', 'level': 3, 'score': 0.449059}, {'id': 'https://openalex.org/C29537977', 'wikidata': 'https://www.wikidata.org/wiki/Q188941', 'display_name': 'Cell cycle', 'level': 3, 'score': 0.36443204}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.35808492}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.25150228}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.23116377}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.13928792}, {'id': 'https://openalex.org/C47432576', 'wikidata': 'https://www.wikidata.org/wiki/Q918594', 'display_name': 'Spindle apparatus', 'level': 4, 'score': 0.09888807}, {'id': 'https://openalex.org/C85813293', 'wikidata': 'https://www.wikidata.org/wiki/Q188909', 'display_name': 'Cell division', 'level': 3, 'score': 0.097993344}, {'id': 'https://openalex.org/C2777576037', 'wikidata': 'https://www.wikidata.org/wiki/Q719725', 'display_name': 'Saccharomyces cerevisiae', 'level': 3, 'score': 0.08623278}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.069025844}], 'mesh': [{'descriptor_ui': 'D002453', 'descriptor_name': 'Cell Cycle', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D018816', 'descriptor_name': 'Genes, cdc', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D010749', 'descriptor_name': 'Phosphoprotein Phosphatases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D011494', 'descriptor_name': 'Protein Kinases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D048948', 'descriptor_name': '14-3-3 Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002453', 'descriptor_name': 'Cell Cycle', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018797', 'descriptor_name': 'Cell Cycle Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D018797', 'descriptor_name': 'Cell Cycle Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000071877', 'descriptor_name': 'Checkpoint Kinase 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D064447', 'descriptor_name': 'Checkpoint Kinase 2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004249', 'descriptor_name': 'DNA Damage', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010749', 'descriptor_name': 'Phosphoprotein Phosphatases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010766', 'descriptor_name': 'Phosphorylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011494', 'descriptor_name': 'Protein Kinases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012568', 'descriptor_name': 'Schizosaccharomyces', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012568', 'descriptor_name': 'Schizosaccharomyces', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D012568', 'descriptor_name': 'Schizosaccharomyces', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D029702', 'descriptor_name': 'Schizosaccharomyces pombe Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D029702', 'descriptor_name': 'Schizosaccharomyces pombe Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014446', 'descriptor_name': 'Tyrosine 3-Monooxygenase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D014446', 'descriptor_name': 'Tyrosine 3-Monooxygenase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.4161/cc.3.5.820', 'pdf_url': 'https://www.tandfonline.com/doi/pdf/10.4161/cc.3.5.820?needAccess=true', 'source': {'id': 'https://openalex.org/S86011449', 'display_name': 'Cell Cycle', 'issn_l': '1551-4005', 'issn': ['1551-4005', '1538-4101'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15020842', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.4161/cc.3.5.820', 'pdf_url': 'https://www.tandfonline.com/doi/pdf/10.4161/cc.3.5.820?needAccess=true', 'source': {'id': 'https://openalex.org/S86011449', 'display_name': 'Cell Cycle', 'issn_l': '1551-4005', 'issn': ['1551-4005', '1538-4101'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W71703021', 'https://openalex.org/W2393250802', 'https://openalex.org/W2329294870', 'https://openalex.org/W2316582027', 'https://openalex.org/W2162730779', 'https://openalex.org/W2159040452', 'https://openalex.org/W2141022069', 'https://openalex.org/W2123955384', 'https://openalex.org/W2072937067', 'https://openalex.org/W2043916245'], 'abstract_inverted_index': {'The': [0], 'G2': [1], 'DNA': [2, 51, 105, 124], 'damage': [3, 52, 125], 'checkpoint': [4, 41, 53, 87, 113, 126, 133], 'prevents': [5], 'mitotic': [6], 'entry': [7], 'in': [8, 32, 102, 109], 'the': [9, 33, 38, 50, 64, 77, 86, 98, 118], 'presence': [10], 'of': [11, 40, 66, 120], 'damaged': [12], 'DNA,': [13], 'and': [14, 107, 112, 128, 135], 'thus': [15], 'is': [16, 54], 'essential': [17], 'for': [18, 132], 'cells': [19], 'to': [20, 48, 57, 104], 'replicate': [21], 'with': [22], 'stable': [23], 'genetic': [24], 'inheritance.': [25], 'Whilst': [26], 'significant': [27], 'progress': [28], 'has': [29, 45], 'been': [30, 46], 'made': [31], 'past': [34], '10': [35], 'years': [36], 'on': [37, 93, 123, 130], 'mechanism': [39, 65], 'activation,': [42], 'little': [43], 'attention': [44], 'paid': [47], 'how': [49], 'switched': [55], 'off': [56], 'allow': [58], 'cell': [59, 67], 'cycle': [60, 68], 're-entry.': [61], 'Insight': [62], 'into': [63], 're-entry': [69], 'was': [70], 'recently': [71], 'provided': [72], 'by': [73, 97], 'our': [74], 'finding': [75, 122], 'that': [76], 'Schizosaccharomyces': [78], 'pombe': [79], 'type': [80], '1': [81], 'phosphatase': [82], '(PP1)': [83], 'Dis2': [84], 'dephosphorylates': [85], 'effector': [88], 'kinase': [89], 'Chk1.': [90], 'This': [91], 'occurs': [92], 'a': [94], 'site': [95], 'phosphorylated': [96], 'ATR': [99], 'homologue': [100], 'Rad3': [101], 'response': [103], 'damage,': [106], 'results': [108], 'Chk1': [110], 'inactivation': [111], 'release.': [114, 136], 'Here': [115], 'we': [116], 'discuss': [117], 'implications': [119], 'this': [121], 'signaling,': [127], 'speculate': [129], 'models': [131], 'maintenance': [134]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2019969911', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 2}], 'updated_date': '2024-12-08T17:51:16.687128', 'created_date': '2016-06-24'}