Publication Information

{'id': 'https://openalex.org/W2316582027', 'doi': 'https://doi.org/10.1038/sj.onc.1204942', 'title': 'Inhibition of Chk1-dependent G2 DNA damage checkpoint radiosensitizes p53 mutant human cells', 'display_name': 'Inhibition of Chk1-dependent G2 DNA damage checkpoint radiosensitizes p53 mutant human cells', 'publication_year': 2001, 'publication_date': '2001-11-08', 'ids': {'openalex': 'https://openalex.org/W2316582027', 'doi': 'https://doi.org/10.1038/sj.onc.1204942', 'mag': '2316582027', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11709716'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1038/sj.onc.1204942', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S128439998', 'display_name': 'Oncogene', 'issn_l': '0950-9232', 'issn': ['0950-9232', '1476-5594'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5089649645', 'display_name': 'Kalli Koniaras', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800555584', 'display_name': 'Peter MacCallum Cancer Centre', 'ror': 'https://ror.org/02a8bt934', 'country_code': 'AU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800555584']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Kalli Koniaras', 'raw_affiliation_strings': ["Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Locked Bag 1, A'Beckett St, Melbourne, 8006, VIC, Australia"], 'affiliations': [{'raw_affiliation_string': "Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Locked Bag 1, A'Beckett St, Melbourne, 8006, VIC, Australia", 'institution_ids': ['https://openalex.org/I2800555584']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047682972', 'display_name': 'Andrew Cuddihy', 'orcid': 'https://orcid.org/0000-0002-9898-0443'}, 'institutions': [{'id': 'https://openalex.org/I2800555584', 'display_name': 'Peter MacCallum Cancer Centre', 'ror': 'https://ror.org/02a8bt934', 'country_code': 'AU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800555584']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Andrew R Cuddihy', 'raw_affiliation_strings': ["Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Locked Bag 1, A'Beckett St, Melbourne, 8006, VIC, Australia"], 'affiliations': [{'raw_affiliation_string': "Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Locked Bag 1, A'Beckett St, Melbourne, 8006, VIC, Australia", 'institution_ids': ['https://openalex.org/I2800555584']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090226296', 'display_name': 'Helen Christopoulos', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800555584', 'display_name': 'Peter MacCallum Cancer Centre', 'ror': 'https://ror.org/02a8bt934', 'country_code': 'AU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800555584']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Helen Christopoulos', 'raw_affiliation_strings': ["Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Locked Bag 1, A'Beckett St, Melbourne, 8006, VIC, Australia"], 'affiliations': [{'raw_affiliation_string': "Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Locked Bag 1, A'Beckett St, Melbourne, 8006, VIC, Australia", 'institution_ids': ['https://openalex.org/I2800555584']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111722708', 'display_name': 'Annette Hogg', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800555584', 'display_name': 'Peter MacCallum Cancer Centre', 'ror': 'https://ror.org/02a8bt934', 'country_code': 'AU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800555584']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Annette Hogg', 'raw_affiliation_strings': ["Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Locked Bag 1, A'Beckett St, Melbourne, 8006, VIC, Australia"], 'affiliations': [{'raw_affiliation_string': "Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Locked Bag 1, A'Beckett St, Melbourne, 8006, VIC, Australia", 'institution_ids': ['https://openalex.org/I2800555584']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5013107841', 'display_name': 'Matthew J. O’Connell', 'orcid': 'https://orcid.org/0000-0002-0061-2504'}, 'institutions': [{'id': 'https://openalex.org/I165779595', 'display_name': 'University of Melbourne', 'ror': 'https://ror.org/01ej9dk98', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I165779595']}], 'countries': ['AU'], 'is_corresponding': True, 'raw_author_name': "Matthew J O'Connell", 'raw_affiliation_strings': ['Department of Genetics, University of Melbourne, Parkville, 3052, VIC, Australia'], 'affiliations': [{'raw_affiliation_string': 'Department of Genetics, University of Melbourne, Parkville, 3052, VIC, Australia', 'institution_ids': ['https://openalex.org/I165779595']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5013107841'], 'corresponding_institution_ids': ['https://openalex.org/I165779595'], 'apc_list': {'value': 4390, 'currency': 'EUR', 'value_usd': 5490, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.166, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 165, 'citation_normalized_percentile': {'value': 0.956847, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '20', 'issue': '51', 'first_page': '7453', 'last_page': '7463'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10583', 'display_name': 'Cancer-related Molecular Pathways', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10583', 'display_name': 'Cancer-related Molecular Pathways', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10123', 'display_name': 'DNA Repair Mechanisms', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10492', 'display_name': 'Microtubule and mitosis dynamics', 'score': 0.9971, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/chek1', 'display_name': 'CHEK1', 'score': 0.8676895}, {'id': 'https://openalex.org/keywords/dna-re-replication', 'display_name': 'DNA re-replication', 'score': 0.4917517}, {'id': 'https://openalex.org/keywords/checkpoint-kinase-2', 'display_name': 'Checkpoint Kinase 2', 'score': 0.43778032}], 'concepts': [{'id': 'https://openalex.org/C50001416', 'wikidata': 'https://www.wikidata.org/wiki/Q17861750', 'display_name': 'CHEK1', 'level': 5, 'score': 0.8676895}, {'id': 'https://openalex.org/C54086632', 'wikidata': 'https://www.wikidata.org/wiki/Q5512671', 'display_name': 'G2-M DNA damage checkpoint', 'level': 5, 'score': 0.84015596}, {'id': 'https://openalex.org/C143425029', 'wikidata': 'https://www.wikidata.org/wiki/Q5205747', 'display_name': 'DNA damage', 'level': 3, 'score': 0.83261555}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.8248135}, {'id': 'https://openalex.org/C105696609', 'wikidata': 'https://www.wikidata.org/wiki/Q1068809', 'display_name': 'Cell cycle checkpoint', 'level': 4, 'score': 0.72510016}, {'id': 'https://openalex.org/C29537977', 'wikidata': 'https://www.wikidata.org/wiki/Q188941', 'display_name': 'Cell cycle', 'level': 3, 'score': 0.7065318}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.62582767}, {'id': 'https://openalex.org/C134935766', 'wikidata': 'https://www.wikidata.org/wiki/Q210538', 'display_name': 'DNA repair', 'level': 3, 'score': 0.60670507}, {'id': 'https://openalex.org/C124320809', 'wikidata': 'https://www.wikidata.org/wiki/Q46292', 'display_name': 'Cyclin-dependent kinase', 'level': 4, 'score': 0.51679575}, {'id': 'https://openalex.org/C67419583', 'wikidata': 'https://www.wikidata.org/wiki/Q5205768', 'display_name': 'DNA re-replication', 'level': 5, 'score': 0.4917517}, {'id': 'https://openalex.org/C2910325170', 'wikidata': 'https://www.wikidata.org/wiki/Q14912280', 'display_name': 'Checkpoint Kinase 2', 'level': 5, 'score': 0.43778032}, {'id': 'https://openalex.org/C178169997', 'wikidata': 'https://www.wikidata.org/wiki/Q2892636', 'display_name': 'Genome instability', 'level': 4, 'score': 0.435947}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.3331078}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.3151672}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.27435422}, {'id': 'https://openalex.org/C98086919', 'wikidata': 'https://www.wikidata.org/wiki/Q118019', 'display_name': 'Eukaryotic DNA replication', 'level': 4, 'score': 0.26155007}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.24394187}], 'mesh': [{'descriptor_ui': 'D004249', 'descriptor_name': 'DNA Damage', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D016158', 'descriptor_name': 'Genes, p53', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D011494', 'descriptor_name': 'Protein Kinases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D011836', 'descriptor_name': 'Radiation Tolerance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D015153', 'descriptor_name': 'Blotting, Western', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002453', 'descriptor_name': 'Cell Cycle', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002453', 'descriptor_name': 'Cell Cycle', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000071877', 'descriptor_name': 'Checkpoint Kinase 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004307', 'descriptor_name': 'Dose-Response Relationship, Radiation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005434', 'descriptor_name': 'Flow Cytometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019084', 'descriptor_name': 'Fluorescent Antibody Technique, Indirect', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016195', 'descriptor_name': 'G2 Phase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005799', 'descriptor_name': 'Genes, Dominant', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016158', 'descriptor_name': 'Genes, p53', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006367', 'descriptor_name': 'HeLa Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008954', 'descriptor_name': 'Models, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010766', 'descriptor_name': 'Phosphorylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011494', 'descriptor_name': 'Protein Kinases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011494', 'descriptor_name': 'Protein Kinases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1038/sj.onc.1204942', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S128439998', 'display_name': 'Oncogene', 'issn_l': '0950-9232', 'issn': ['0950-9232', '1476-5594'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11709716', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.85}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 52, 'referenced_works': ['https://openalex.org/W147930742', 'https://openalex.org/W1538460486', 'https://openalex.org/W1544851750', 'https://openalex.org/W1558906202', 'https://openalex.org/W177968855', 'https://openalex.org/W1847864430', 'https://openalex.org/W1967880683', 'https://openalex.org/W1977541278', 'https://openalex.org/W1978222385', 'https://openalex.org/W1990819034', 'https://openalex.org/W1991494214', 'https://openalex.org/W1994066190', 'https://openalex.org/W1994163195', 'https://openalex.org/W2007305884', 'https://openalex.org/W2015519364', 'https://openalex.org/W2019918282', 'https://openalex.org/W2021230221', 'https://openalex.org/W2024218128', 'https://openalex.org/W2026669341', 'https://openalex.org/W2028044172', 'https://openalex.org/W2033950216', 'https://openalex.org/W2055206436', 'https://openalex.org/W2064554826', 'https://openalex.org/W2065624759', 'https://openalex.org/W2072720547', 'https://openalex.org/W2080125477', 'https://openalex.org/W2089574530', 'https://openalex.org/W2103675400', 'https://openalex.org/W2105592350', 'https://openalex.org/W2105768236', 'https://openalex.org/W2106410559', 'https://openalex.org/W2109408011', 'https://openalex.org/W2111403239', 'https://openalex.org/W2112481873', 'https://openalex.org/W2113684644', 'https://openalex.org/W2120921507', 'https://openalex.org/W2121619780', 'https://openalex.org/W2125003296', 'https://openalex.org/W2127849733', 'https://openalex.org/W2130603065', 'https://openalex.org/W2131833681', 'https://openalex.org/W2133318290', 'https://openalex.org/W2137108719', 'https://openalex.org/W2147288798', 'https://openalex.org/W2148958834', 'https://openalex.org/W2154141161', 'https://openalex.org/W2155487282', 'https://openalex.org/W2155640249', 'https://openalex.org/W2167196101', 'https://openalex.org/W2171251720', 'https://openalex.org/W2888511473', 'https://openalex.org/W42123934'], 'related_works': ['https://openalex.org/W781610663', 'https://openalex.org/W2148228855', 'https://openalex.org/W2132984079', 'https://openalex.org/W2072868975', 'https://openalex.org/W2055206436', 'https://openalex.org/W1997759534', 'https://openalex.org/W1997269681', 'https://openalex.org/W1986121915', 'https://openalex.org/W1969264931', 'https://openalex.org/W1887764107'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2316582027', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 7}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 6}, {'year': 2013, 'cited_by_count': 13}, {'year': 2012, 'cited_by_count': 13}], 'updated_date': '2024-12-23T19:22:32.415841', 'created_date': '2016-06-24'}