Publication Information

{'id': 'https://openalex.org/W54757434', 'doi': None, 'title': '[Capsaicin receptor TRPV1].', 'display_name': '[Capsaicin receptor TRPV1].', 'publication_year': 2008, 'publication_date': '2008-05-01', 'ids': {'openalex': 'https://openalex.org/W54757434', 'mag': '54757434', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/18516971'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://europepmc.org/article/MED/18516971', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2755800491', 'display_name': 'Brain and nerve', 'issn_l': '1344-8129', 'issn': ['1344-8129', '1881-6096'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319747', 'host_organization_name': 'Igaku Shoin', 'host_organization_lineage': ['https://openalex.org/P4310319747'], 'host_organization_lineage_names': ['Igaku Shoin'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5074653699', 'display_name': 'Makoto Tominaga', 'orcid': 'https://orcid.org/0000-0003-3111-3772'}, 'institutions': [{'id': 'https://openalex.org/I199525922', 'display_name': 'National Institutes of Natural Sciences', 'ror': 'https://ror.org/055n47h92', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I1319490839', 'https://openalex.org/I199525922']}, {'id': 'https://openalex.org/I4210097088', 'display_name': 'Okazaki Institute for Integrative Bioscience', 'ror': 'https://ror.org/00v3cq569', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I4210097088']}, {'id': 'https://openalex.org/I4210145863', 'display_name': 'National Institute for Physiological Sciences', 'ror': 'https://ror.org/048v13307', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I1319490839', 'https://openalex.org/I199525922', 'https://openalex.org/I4210145863']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Makoto Tominaga', 'raw_affiliation_strings': ['Section of Cell Signaling, Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), National Institutes of Natural Sciences, Higashiyama 5-1, Myodaiji, Okazaki, Aichi 444-8787, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Section of Cell Signaling, Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), National Institutes of Natural Sciences, Higashiyama 5-1, Myodaiji, Okazaki, Aichi 444-8787, Japan.', 'institution_ids': ['https://openalex.org/I199525922', 'https://openalex.org/I4210097088', 'https://openalex.org/I4210145863']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5074653699'], 'corresponding_institution_ids': ['https://openalex.org/I199525922', 'https://openalex.org/I4210097088', 'https://openalex.org/I4210145863'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.241, 'has_fulltext': False, 'cited_by_count': 8, 'citation_normalized_percentile': {'value': 0.462654, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 82, 'max': 83}, 'biblio': {'volume': '60', 'issue': '5', 'first_page': '493', 'last_page': '501'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11204', 'display_name': 'Ion Channels and Receptors', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2809', 'display_name': 'Sensory Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11204', 'display_name': 'Ion Channels and Receptors', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2809', 'display_name': 'Sensory Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12418', 'display_name': 'Respiratory and Cough-Related Research', 'score': 0.9181, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13483', 'display_name': 'Herbal Medicine Research Studies', 'score': 0.9141, 'subfield': {'id': 'https://openalex.org/subfields/2707', 'display_name': 'Complementary and alternative medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/capsaicin', 'display_name': 'Capsaicin', 'score': 0.874398}, {'id': 'https://openalex.org/keywords/heterologous-expression', 'display_name': 'Heterologous expression', 'score': 0.75100046}, {'id': 'https://openalex.org/keywords/heterologous', 'display_name': 'Heterologous', 'score': 0.5284847}], 'concepts': [{'id': 'https://openalex.org/C160145004', 'wikidata': 'https://www.wikidata.org/wiki/Q413209', 'display_name': 'TRPV1', 'level': 4, 'score': 0.9783016}, {'id': 'https://openalex.org/C2780051329', 'wikidata': 'https://www.wikidata.org/wiki/Q273169', 'display_name': 'Capsaicin', 'level': 3, 'score': 0.874398}, {'id': 'https://openalex.org/C155164980', 'wikidata': 'https://www.wikidata.org/wiki/Q304043', 'display_name': 'Transient receptor potential channel', 'level': 3, 'score': 0.8580843}, {'id': 'https://openalex.org/C108305142', 'wikidata': 'https://www.wikidata.org/wiki/Q3062286', 'display_name': 'Heterologous expression', 'level': 4, 'score': 0.75100046}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.5551364}, {'id': 'https://openalex.org/C2780115692', 'wikidata': 'https://www.wikidata.org/wiki/Q5747302', 'display_name': 'Heterologous', 'level': 3, 'score': 0.5284847}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.52241516}, {'id': 'https://openalex.org/C92028520', 'wikidata': 'https://www.wikidata.org/wiki/Q7395025', 'display_name': 'SUPERFAMILY', 'level': 3, 'score': 0.46712002}, {'id': 'https://openalex.org/C15490471', 'wikidata': 'https://www.wikidata.org/wiki/Q2734305', 'display_name': 'Nociception', 'level': 3, 'score': 0.45354593}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.4416055}, {'id': 'https://openalex.org/C2780820201', 'wikidata': 'https://www.wikidata.org/wiki/Q173235', 'display_name': 'Analgesic', 'level': 2, 'score': 0.43001646}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.3512637}, {'id': 'https://openalex.org/C40767141', 'wikidata': 'https://www.wikidata.org/wiki/Q285697', 'display_name': 'Recombinant DNA', 'level': 3, 'score': 0.3294166}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.22298059}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.21657023}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.08373392}], 'mesh': [{'descriptor_ui': 'D050916', 'descriptor_name': 'TRPV Cation Channels', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000700', 'descriptor_name': 'Analgesics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003001', 'descriptor_name': 'Cloning, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015195', 'descriptor_name': 'Drug Design', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010146', 'descriptor_name': 'Pain', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010146', 'descriptor_name': 'Pain', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D010146', 'descriptor_name': 'Pain', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D000074025', 'descriptor_name': 'TRPA1 Cation Channel', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050916', 'descriptor_name': 'TRPV Cation Channels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050916', 'descriptor_name': 'TRPV Cation Channels', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D050916', 'descriptor_name': 'TRPV Cation Channels', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D050916', 'descriptor_name': 'TRPV Cation Channels', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D050051', 'descriptor_name': 'Transient Receptor Potential Channels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050051', 'descriptor_name': 'Transient Receptor Potential Channels', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://europepmc.org/article/MED/18516971', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2755800491', 'display_name': 'Brain and nerve', 'issn_l': '1344-8129', 'issn': ['1344-8129', '1881-6096'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319747', 'host_organization_name': 'Igaku Shoin', 'host_organization_lineage': ['https://openalex.org/P4310319747'], 'host_organization_lineage_names': ['Igaku Shoin'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/18516971', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3113291031', 'https://openalex.org/W3045649813', 'https://openalex.org/W3023338839', 'https://openalex.org/W2567538899', 'https://openalex.org/W2498122211', 'https://openalex.org/W2329332441', 'https://openalex.org/W2201147674', 'https://openalex.org/W2145740488', 'https://openalex.org/W2121599441', 'https://openalex.org/W2055523116', 'https://openalex.org/W2046955207', 'https://openalex.org/W2033842010', 'https://openalex.org/W1995953203', 'https://openalex.org/W1990417198', 'https://openalex.org/W1982567554', 'https://openalex.org/W1965509871', 'https://openalex.org/W1583631091', 'https://openalex.org/W1527988408', 'https://openalex.org/W11021697', 'https://openalex.org/W10864851'], 'abstract_inverted_index': {'Transient': [0], 'receptor': [1, 8], 'potential': [2], 'vanilloid': [3], '1': [4], '(TRPV1)': [5], 'is': [6, 12, 33], 'a': [7, 13, 81], 'for': [9], 'capsaicin,': [10], 'which': [11], 'main': [14], 'ingredient': [15], 'in': [16, 47, 94, 132], 'hot': [17], 'chili': [18], 'peppers,': [19], 'and': [20, 43, 56, 97, 99], 'belongs': [21], 'to': [22], 'the': [23, 48, 53, 71, 91, 100, 111, 130, 133], 'TRP': [24], 'ion': [25], 'channel': [26], 'superfamily.': [27], 'Researchers': [28], 'have': [29], 'confirmed': [30], 'that': [31], 'TRPV1': [32, 66, 77, 114], 'activated': [34], 'by': [35], 'multiple': [36], 'nociceptive': [37], 'stimuli': [38], 'including': [39], 'protons,': [40], 'noxious': [41], 'heat': [42], 'some': [44, 124], 'lipids': [45], 'both': [46], 'heterologous': [49], 'expression': [50], 'system': [51], 'using': [52, 63], 'cloned': [54], 'channels': [55], 'native': [57], 'sensory': [58], 'neurons.': [59], 'In': [60], 'addition,': [61], 'studies': [62], 'mice': [64], 'lacking': [65], 'revealed': [67], 'its': [68, 89, 95], 'importance': [69], 'at': [70], 'behavioral': [72], 'level.': [73], 'Since': [74], '1997,': [75], 'when': [76], 'was': [78], 'first': [79], 'cloned,': [80], 'considerable': [82], 'amount': [83], 'of': [84, 103, 113, 125], 'information': [85], 'has': [86], 'accumulated': [87], 'regarding': [88], 'agonists,': [90], 'mechanisms': [92], 'involved': [93], 'activation': [96], 'regulation,': [98], 'structural': [101], 'bases': [102], 'these': [104, 126], 'mechanisms.': [105], 'Furthermore,': [106], 'several': [107], 'clinical': [108], 'trials': [109], 'involving': [110], 'use': [112], 'antagonists': [115], 'as': [116], 'analgesic': [117], 'agents': [118, 127], 'are': [119], 'currently': [120], 'underway.': [121], 'With': [122], 'success,': [123], 'may': [128], 'enter': [129], 'market': [131], 'near': [134], 'future.': [135]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W54757434', 'counts_by_year': [{'year': 2019, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 2}], 'updated_date': '2024-12-14T13:38:11.259772', 'created_date': '2016-06-24'}