Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2567538899', 'doi': 'https://doi.org/10.1002/med.21427', 'title': 'Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists', 'display_name': 'Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists', 'publication_year': 2016, 'publication_date': '2016-12-15', 'ids': {'openalex': 'https://openalex.org/W2567538899', 'doi': 'https://doi.org/10.1002/med.21427', 'mag': '2567538899', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/27976413'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/med.21427', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S22382660', 'display_name': 'Medicinal Research Reviews', 'issn_l': '0198-6325', 'issn': ['0198-6325', '1098-1128'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://iris.unife.it/bitstream/11392/2360036/8/2360036%20pre-print.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5033429648', 'display_name': 'Mojgan Aghazadeh Tabrizi', 'orcid': 'https://orcid.org/0000-0001-9350-5208'}, 'institutions': [{'id': 'https://openalex.org/I201324441', 'display_name': 'University of Ferrara', 'ror': 'https://ror.org/041zkgm14', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I201324441']}], 'countries': ['IT'], 'is_corresponding': True, 'raw_author_name': 'Mojgan Aghazadeh Tabrizi', 'raw_affiliation_strings': ['Department of Chemical and Pharmaceutical Sciences University of Ferrara 44121 Ferrara Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemical and Pharmaceutical Sciences University of Ferrara 44121 Ferrara Italy', 'institution_ids': ['https://openalex.org/I201324441']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063804577', 'display_name': 'Pier Giovanni Baraldi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I201324441', 'display_name': 'University of Ferrara', 'ror': 'https://ror.org/041zkgm14', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I201324441']}], 'countries': ['IT'], 'is_corresponding': True, 'raw_author_name': 'Pier Giovanni Baraldi', 'raw_affiliation_strings': ['Department of Chemical and Pharmaceutical Sciences University of Ferrara 44121 Ferrara Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemical and Pharmaceutical Sciences University of Ferrara 44121 Ferrara Italy', 'institution_ids': ['https://openalex.org/I201324441']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007328509', 'display_name': 'Stefania Baraldi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I201324441', 'display_name': 'University of Ferrara', 'ror': 'https://ror.org/041zkgm14', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I201324441']}], 'countries': ['IT'], 'is_corresponding': True, 'raw_author_name': 'Stefania Baraldi', 'raw_affiliation_strings': ['Department of Chemical and Pharmaceutical Sciences University of Ferrara 44121 Ferrara Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemical and Pharmaceutical Sciences University of Ferrara 44121 Ferrara Italy', 'institution_ids': ['https://openalex.org/I201324441']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020435407', 'display_name': 'Stefania Gessi', 'orcid': 'https://orcid.org/0000-0002-2197-5611'}, 'institutions': [{'id': 'https://openalex.org/I201324441', 'display_name': 'University of Ferrara', 'ror': 'https://ror.org/041zkgm14', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I201324441']}], 'countries': ['IT'], 'is_corresponding': True, 'raw_author_name': 'Stefania Gessi', 'raw_affiliation_strings': ['Section of Pharmacology, Department of Medical Sciences University of Ferrara 44121 Ferrara Italy'], 'affiliations': [{'raw_affiliation_string': 'Section of Pharmacology, Department of Medical Sciences University of Ferrara 44121 Ferrara Italy', 'institution_ids': ['https://openalex.org/I201324441']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027485003', 'display_name': 'Stefania Merighi', 'orcid': 'https://orcid.org/0000-0003-0839-6671'}, 'institutions': [{'id': 'https://openalex.org/I201324441', 'display_name': 'University of Ferrara', 'ror': 'https://ror.org/041zkgm14', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I201324441']}], 'countries': ['IT'], 'is_corresponding': True, 'raw_author_name': 'Stefania Merighi', 'raw_affiliation_strings': ['Section of Pharmacology, Department of Medical Sciences University of Ferrara 44121 Ferrara Italy'], 'affiliations': [{'raw_affiliation_string': 'Section of Pharmacology, Department of Medical Sciences University of Ferrara 44121 Ferrara Italy', 'institution_ids': ['https://openalex.org/I201324441']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5013716423', 'display_name': 'Pier Andrea Borea', 'orcid': 'https://orcid.org/0000-0003-1118-9171'}, 'institutions': [{'id': 'https://openalex.org/I201324441', 'display_name': 'University of Ferrara', 'ror': 'https://ror.org/041zkgm14', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I201324441']}], 'countries': ['IT'], 'is_corresponding': True, 'raw_author_name': 'Pier Andrea Borea', 'raw_affiliation_strings': ['Section of Pharmacology, Department of Medical Sciences University of Ferrara 44121 Ferrara Italy'], 'affiliations': [{'raw_affiliation_string': 'Section of Pharmacology, Department of Medical Sciences University of Ferrara 44121 Ferrara Italy', 'institution_ids': ['https://openalex.org/I201324441']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5033429648', 'https://openalex.org/A5063804577', 'https://openalex.org/A5007328509', 'https://openalex.org/A5020435407', 'https://openalex.org/A5027485003', 'https://openalex.org/A5013716423'], 'corresponding_institution_ids': ['https://openalex.org/I201324441', 'https://openalex.org/I201324441', 'https://openalex.org/I201324441', 'https://openalex.org/I201324441', 'https://openalex.org/I201324441', 'https://openalex.org/I201324441'], 'apc_list': {'value': 4740, 'currency': 'USD', 'value_usd': 4740, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.895, 'has_fulltext': False, 'cited_by_count': 152, 'citation_normalized_percentile': {'value': 0.504237, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '37', 'issue': '4', 'first_page': '936', 'last_page': '983'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11204', 'display_name': 'Ion Channels and Receptors', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2809', 'display_name': 'Sensory Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11204', 'display_name': 'Ion Channels and Receptors', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2809', 'display_name': 'Sensory Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13483', 'display_name': 'Herbal Medicine Research Studies', 'score': 0.9944, 'subfield': {'id': 'https://openalex.org/subfields/2707', 'display_name': 'Complementary and alternative medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10035', 'display_name': 'Phytochemicals and Antioxidant Activities', 'score': 0.9842, 'subfield': {'id': 'https://openalex.org/subfields/2704', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/resiniferatoxin', 'display_name': 'Resiniferatoxin', 'score': 0.92747724}], 'concepts': [{'id': 'https://openalex.org/C160145004', 'wikidata': 'https://www.wikidata.org/wiki/Q413209', 'display_name': 'TRPV1', 'level': 4, 'score': 0.95219845}, {'id': 'https://openalex.org/C2776354303', 'wikidata': 'https://www.wikidata.org/wiki/Q3277888', 'display_name': 'Resiniferatoxin', 'level': 5, 'score': 0.92747724}, {'id': 'https://openalex.org/C155164980', 'wikidata': 'https://www.wikidata.org/wiki/Q304043', 'display_name': 'Transient receptor potential channel', 'level': 3, 'score': 0.73909134}, {'id': 'https://openalex.org/C2781118164', 'wikidata': 'https://www.wikidata.org/wiki/Q1088113', 'display_name': 'Chronic pain', 'level': 2, 'score': 0.5493899}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.47814715}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.4747874}, {'id': 'https://openalex.org/C135285700', 'wikidata': 'https://www.wikidata.org/wiki/Q38173', 'display_name': 'G protein-coupled receptor', 'level': 3, 'score': 0.43918636}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.42805246}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.40553817}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.36500213}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.16491178}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.1241695}], 'mesh': [{'descriptor_ui': 'D002211', 'descriptor_name': 'Capsaicin', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': True}, {'descriptor_ui': 'D050916', 'descriptor_name': 'TRPV Cation Channels', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D050916', 'descriptor_name': 'TRPV Cation Channels', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002211', 'descriptor_name': 'Capsaicin', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D002211', 'descriptor_name': 'Capsaicin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D002211', 'descriptor_name': 'Capsaicin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002626', 'descriptor_name': 'Chemistry, Pharmaceutical', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013329', 'descriptor_name': 'Structure-Activity Relationship', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050916', 'descriptor_name': 'TRPV Cation Channels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050916', 'descriptor_name': 'TRPV Cation Channels', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D050916', 'descriptor_name': 'TRPV Cation Channels', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/med.21427', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S22382660', 'display_name': 'Medicinal Research Reviews', 'issn_l': '0198-6325', 'issn': ['0198-6325', '1098-1128'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/11392/2360036', 'pdf_url': 'https://iris.unife.it/bitstream/11392/2360036/8/2360036%20pre-print.pdf', 'source': {'id': 'https://openalex.org/S4306400369', 'display_name': 'Institutional Research Information System University of Ferrara (University of Ferrara)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I201324441', 'host_organization_name': 'University of Ferrara', 'host_organization_lineage': ['https://openalex.org/I201324441'], 'host_organization_lineage_names': ['University of Ferrara'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/27976413', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/11392/2360036', 'pdf_url': 'https://iris.unife.it/bitstream/11392/2360036/8/2360036%20pre-print.pdf', 'source': {'id': 'https://openalex.org/S4306400369', 'display_name': 'Institutional Research Information System University of Ferrara (University of Ferrara)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I201324441', 'host_organization_name': 'University of Ferrara', 'host_organization_lineage': ['https://openalex.org/I201324441'], 'host_organization_lineage_names': ['University of Ferrara'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.84}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 298, 'referenced_works': ['https://openalex.org/W1481062928', 'https://openalex.org/W1485008662', 'https://openalex.org/W1488329806', 'https://openalex.org/W1492591187', 'https://openalex.org/W1493455024', 'https://openalex.org/W1511198581', 'https://openalex.org/W1539388364', 'https://openalex.org/W1541402772', 'https://openalex.org/W1543318481', 'https://openalex.org/W1556476483', 'https://openalex.org/W1571837352', 'https://openalex.org/W1571969265', 'https://openalex.org/W1577496155', 'https://openalex.org/W1578927000', 'https://openalex.org/W1582245657', 'https://openalex.org/W1707413311', 'https://openalex.org/W1719691205', 'https://openalex.org/W1720198876', 'https://openalex.org/W173334039', 'https://openalex.org/W1740681156', 'https://openalex.org/W1892718850', 'https://openalex.org/W1963857381', 'https://openalex.org/W1964302331', 'https://openalex.org/W1964358846', 'https://openalex.org/W1964531781', 'https://openalex.org/W1964925166', 'https://openalex.org/W1965509871', 'https://openalex.org/W1965925550', 'https://openalex.org/W1969233157', 'https://openalex.org/W1971566600', 'https://openalex.org/W1971754431', 'https://openalex.org/W1972359448', 'https://openalex.org/W1973003628', 'https://openalex.org/W1974107068', 'https://openalex.org/W1976071036', 'https://openalex.org/W1976550936', 'https://openalex.org/W1977616513', 'https://openalex.org/W1977982128', 'https://openalex.org/W1979902669', 'https://openalex.org/W1981632311', 'https://openalex.org/W1982389733', 'https://openalex.org/W1982629087', 'https://openalex.org/W1983808266', 'https://openalex.org/W1984033377', 'https://openalex.org/W1984730602', 'https://openalex.org/W1985030046', 'https://openalex.org/W1985163057', 'https://openalex.org/W1986235007', 'https://openalex.org/W1986255684', 'https://openalex.org/W1988036253', 'https://openalex.org/W1988375390', 'https://openalex.org/W1988531294', 'https://openalex.org/W1988853287', 'https://openalex.org/W1989148461', 'https://openalex.org/W1990427801', 'https://openalex.org/W1991633373', 'https://openalex.org/W1991956843', 'https://openalex.org/W1993431922', 'https://openalex.org/W1994846851', 'https://openalex.org/W1995705528', 'https://openalex.org/W1995730999', 'https://openalex.org/W1996303646', 'https://openalex.org/W1997517400', 'https://openalex.org/W1998167811', 'https://openalex.org/W1999665243', 'https://openalex.org/W2000953416', 'https://openalex.org/W2001585316', 'https://openalex.org/W2002347510', 'https://openalex.org/W2003642068', 'https://openalex.org/W2003706636', 'https://openalex.org/W2004222535', 'https://openalex.org/W2004728887', 'https://openalex.org/W2005505879', 'https://openalex.org/W2005557273', 'https://openalex.org/W2006132476', 'https://openalex.org/W2006401652', 'https://openalex.org/W2006726845', 'https://openalex.org/W2007900194', 'https://openalex.org/W2008045899', 'https://openalex.org/W2008048120', 'https://openalex.org/W2008217956', 'https://openalex.org/W2008960710', 'https://openalex.org/W2011008837', 'https://openalex.org/W2011904838', 'https://openalex.org/W2011909645', 'https://openalex.org/W2013656076', 'https://openalex.org/W2013895975', 'https://openalex.org/W2015834221', 'https://openalex.org/W2016034906', 'https://openalex.org/W2017047663', 'https://openalex.org/W2017445997', 'https://openalex.org/W2017579145', 'https://openalex.org/W2018814467', 'https://openalex.org/W2018920575', 'https://openalex.org/W2019434893', 'https://openalex.org/W2020520223', 'https://openalex.org/W2021033497', 'https://openalex.org/W2021815265', 'https://openalex.org/W2021816134', 'https://openalex.org/W2022023122', 'https://openalex.org/W2022819833', 'https://openalex.org/W2023811550', 'https://openalex.org/W2026446002', 'https://openalex.org/W2026545561', 'https://openalex.org/W2028166367', 'https://openalex.org/W2028354668', 'https://openalex.org/W2029360579', 'https://openalex.org/W2029834005', 'https://openalex.org/W2030986287', 'https://openalex.org/W2031353654', 'https://openalex.org/W2032021885', 'https://openalex.org/W2032250203', 'https://openalex.org/W2033425777', 'https://openalex.org/W2033576768', 'https://openalex.org/W2034458389', 'https://openalex.org/W2035429056', 'https://openalex.org/W2035688841', 'https://openalex.org/W2036878047', 'https://openalex.org/W2037153938', 'https://openalex.org/W2039155621', 'https://openalex.org/W2039295918', 'https://openalex.org/W2039522435', 'https://openalex.org/W2040593216', 'https://openalex.org/W2040625818', 'https://openalex.org/W2041546619', 'https://openalex.org/W2042029726', 'https://openalex.org/W2042320851', 'https://openalex.org/W2042427403', 'https://openalex.org/W2042489135', 'https://openalex.org/W2042628484', 'https://openalex.org/W2044632947', 'https://openalex.org/W2045592577', 'https://openalex.org/W2045626430', 'https://openalex.org/W2045737598', 'https://openalex.org/W2046677990', 'https://openalex.org/W2048883209', 'https://openalex.org/W2049100687', 'https://openalex.org/W2050519455', 'https://openalex.org/W2050781058', 'https://openalex.org/W2050792388', 'https://openalex.org/W2051684012', 'https://openalex.org/W2052574406', 'https://openalex.org/W2053170393', 'https://openalex.org/W2053870433', 'https://openalex.org/W2055100907', 'https://openalex.org/W2055335617', 'https://openalex.org/W2056514314', 'https://openalex.org/W2056881398', 'https://openalex.org/W2057039966', 'https://openalex.org/W2057468498', 'https://openalex.org/W2059636104', 'https://openalex.org/W2060934690', 'https://openalex.org/W2061123315', 'https://openalex.org/W2061627146', 'https://openalex.org/W2062139391', 'https://openalex.org/W2063286825', 'https://openalex.org/W2063338540', 'https://openalex.org/W2063654396', 'https://openalex.org/W2064374911', 'https://openalex.org/W2064441047', 'https://openalex.org/W2064938525', 'https://openalex.org/W2065222114', 'https://openalex.org/W2065687666', 'https://openalex.org/W2065840181', 'https://openalex.org/W2066451287', 'https://openalex.org/W2066559312', 'https://openalex.org/W2066590201', 'https://openalex.org/W2068168026', 'https://openalex.org/W2068431213', 'https://openalex.org/W2070948590', 'https://openalex.org/W2071276684', 'https://openalex.org/W2071987240', 'https://openalex.org/W2073606727', 'https://openalex.org/W2075838219', 'https://openalex.org/W2076249178', 'https://openalex.org/W2076268206', 'https://openalex.org/W2077203886', 'https://openalex.org/W2077225258', 'https://openalex.org/W2078859577', 'https://openalex.org/W2079265063', 'https://openalex.org/W2080252996', 'https://openalex.org/W2080281611', 'https://openalex.org/W2081223380', 'https://openalex.org/W2081550686', 'https://openalex.org/W2082938503', 'https://openalex.org/W2083189824', 'https://openalex.org/W2083484726', 'https://openalex.org/W2085446663', 'https://openalex.org/W2085463877', 'https://openalex.org/W2085802434', 'https://openalex.org/W2086021047', 'https://openalex.org/W2087243725', 'https://openalex.org/W2087353420', 'https://openalex.org/W2087381327', 'https://openalex.org/W2087677022', 'https://openalex.org/W2088764206', 'https://openalex.org/W2090974295', 'https://openalex.org/W2091944546', 'https://openalex.org/W2094014495', 'https://openalex.org/W2094446280', 'https://openalex.org/W2094758067', 'https://openalex.org/W2099414466', 'https://openalex.org/W2100291674', 'https://openalex.org/W2100997560', 'https://openalex.org/W2101007294', 'https://openalex.org/W2102129421', 'https://openalex.org/W2103744963', 'https://openalex.org/W2104726039', 'https://openalex.org/W2105746545', 'https://openalex.org/W2106064607', 'https://openalex.org/W2107705149', 'https://openalex.org/W2107756388', 'https://openalex.org/W2110121007', 'https://openalex.org/W2114287206', 'https://openalex.org/W2115765337', 'https://openalex.org/W2117301151', 'https://openalex.org/W2117760396', 'https://openalex.org/W2118626190', 'https://openalex.org/W2119608943', 'https://openalex.org/W2121699381', 'https://openalex.org/W2122071004', 'https://openalex.org/W2122778205', 'https://openalex.org/W2123486904', 'https://openalex.org/W2123673561', 'https://openalex.org/W2124141753', 'https://openalex.org/W2125598231', 'https://openalex.org/W2127140021', 'https://openalex.org/W2127420494', 'https://openalex.org/W2128799695', 'https://openalex.org/W2129900856', 'https://openalex.org/W2130600650', 'https://openalex.org/W2131182476', 'https://openalex.org/W2133692827', 'https://openalex.org/W2133738718', 'https://openalex.org/W2134661192', 'https://openalex.org/W2134742719', 'https://openalex.org/W2134984662', 'https://openalex.org/W2136346599', 'https://openalex.org/W2137445147', 'https://openalex.org/W2138461506', 'https://openalex.org/W2138564138', 'https://openalex.org/W2139345991', 'https://openalex.org/W2149029883', 'https://openalex.org/W2149855043', 'https://openalex.org/W2154266919', 'https://openalex.org/W2154430294', 'https://openalex.org/W2155933772', 'https://openalex.org/W2160975667', 'https://openalex.org/W2162643873', 'https://openalex.org/W2163294871', 'https://openalex.org/W2163841453', 'https://openalex.org/W2164144654', 'https://openalex.org/W2164659462', 'https://openalex.org/W2166894850', 'https://openalex.org/W2167991342', 'https://openalex.org/W2168210103', 'https://openalex.org/W2168621999', 'https://openalex.org/W2170389215', 'https://openalex.org/W2170794739', 'https://openalex.org/W2171717653', 'https://openalex.org/W2205052709', 'https://openalex.org/W2209592921', 'https://openalex.org/W2211548376', 'https://openalex.org/W2212776737', 'https://openalex.org/W2230336731', 'https://openalex.org/W2234754805', 'https://openalex.org/W2260781004', 'https://openalex.org/W2262934115', 'https://openalex.org/W2270955613', 'https://openalex.org/W2277285115', 'https://openalex.org/W2279916199', 'https://openalex.org/W2285722094', 'https://openalex.org/W2307589858', 'https://openalex.org/W2307803645', 'https://openalex.org/W2309440556', 'https://openalex.org/W2321950901', 'https://openalex.org/W2326624180', 'https://openalex.org/W2341598415', 'https://openalex.org/W2346910983', 'https://openalex.org/W238299659', 'https://openalex.org/W2404622021', 'https://openalex.org/W2405656535', 'https://openalex.org/W2412204385', 'https://openalex.org/W2417748670', 'https://openalex.org/W2419494100', 'https://openalex.org/W2441719627', 'https://openalex.org/W2497983820', 'https://openalex.org/W2498122211', 'https://openalex.org/W2505777416', 'https://openalex.org/W2508427169', 'https://openalex.org/W2600648449', 'https://openalex.org/W2605239565', 'https://openalex.org/W4234591059', 'https://openalex.org/W4240352843', 'https://openalex.org/W4250767150', 'https://openalex.org/W4252015878', 'https://openalex.org/W80711335', 'https://openalex.org/W97582216'], 'related_works': ['https://openalex.org/W2964958677', 'https://openalex.org/W2748693184', 'https://openalex.org/W2508427169', 'https://openalex.org/W2356671327', 'https://openalex.org/W2212776737', 'https://openalex.org/W2061247861', 'https://openalex.org/W2058078905', 'https://openalex.org/W2041613015', 'https://openalex.org/W2028264226', 'https://openalex.org/W1542157645'], 'abstract_inverted_index': {'Abstract': [0], 'Transient': [1], 'receptor': [2, 56, 124], 'potential': [3], 'vanilloid': [4], '1': [5], '(TRPV1)': [6], 'is': [7, 90, 105], 'an': [8, 16], 'ion': [9], 'channel': [10, 146], 'expressed': [11], 'on': [12, 179], 'sensory': [13], 'neurons': [14], 'triggering': [15], 'influx': [17], 'of': [18, 63, 110, 128, 158, 166, 174], 'cations.': [19], 'TRPV1': [20, 58, 76, 103, 123, 169], 'receptors': [21], 'function': [22], 'as': [23, 60, 97], 'homotetramers': [24], 'responsive': [25], 'to': [26, 42, 71, 81, 163, 182], 'heat,': [27], 'proinflammatory': [28], 'substances,': [29], 'lipoxygenase': [30], 'products,': [31], 'resiniferatoxin,': [32], 'endocannabinoids,': [33], 'protons,': [34], 'and': [35, 45, 66, 74, 85, 100, 113, 137, 171], 'peptide': [36], 'toxins.': [37], 'Its': [38, 88], 'phosphorylation': [39], 'increases': [40], 'sensitivity': [41], 'both': [43], 'chemical': [44], 'thermal': [46], 'stimuli,': [47], 'while': [48], 'desensitization': [49], 'involves': [50], 'a': [51, 61, 69, 119, 149], 'calcium‐dependent': [52], 'mechanism': [53], 'resulting': [54], 'in': [55, 93, 125], 'dephosphorylation.': [57], 'functions': [59], 'sensor': [62], 'noxious': [64], 'stimuli': [65], 'may': [67], 'represent': [68], 'target': [70, 183], 'avoid': [72], 'pain': [73, 84], 'injury.': [75], 'activation': [77, 104], 'has': [78], 'been': [79], 'associated': [80], 'chronic': [82, 129], 'inflammatory': [83], 'peripheral': [86], 'neuropathy.': [87], 'expression': [89], 'also': [91], 'detected': [92], 'nonneuronal': [94], 'areas': [95], 'such': [96], 'bladder,': [98], 'lungs,': [99], 'cochlea': [101], 'where': [102], 'responsible': [106], 'for': [107], 'pathology': [108], 'development': [109, 143], 'cystitis,': [111], 'asthma,': [112], 'hearing': [114, 138], 'loss.': [115], 'This': [116], 'review': [117], 'offers': [118], 'comprehensive': [120], 'overview': [121], 'about': [122], 'the': [126, 156, 164], 'pathophysiology': [127], 'pain,': [130], 'epilepsy,': [131], 'cough,': [132], 'bladder': [133], 'disorders,': [134], 'diabetes,': [135], 'obesity,': [136], 'loss,': [139], 'highlighting': [140], 'how': [141], 'drug': [142], 'targeting': [144], 'this': [145, 184], 'could': [147], 'have': [148], 'clinical': [150], 'therapeutic': [151], 'potential.': [152], 'Furthermore,': [153], 'it': [154], 'summarizes': [155], 'advances': [157], 'medicinal': [159], 'chemistry': [160], 'research': [161], 'leading': [162], 'identification': [165], 'highly': [167], 'selective': [168], 'antagonists': [170], 'their': [172], 'analysis': [173], 'structure–activity': [175], 'relationships': [176], '(SARs)': [177], 'focusing': [178], 'new': [180], 'strategies': [181], 'channel.': [185]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2567538899', 'counts_by_year': [{'year': 2024, 'cited_by_count': 39}, {'year': 2023, 'cited_by_count': 26}, {'year': 2022, 'cited_by_count': 26}, {'year': 2021, 'cited_by_count': 18}, {'year': 2020, 'cited_by_count': 9}, {'year': 2019, 'cited_by_count': 14}, {'year': 2018, 'cited_by_count': 16}, {'year': 2017, 'cited_by_count': 3}], 'updated_date': '2024-12-25T00:58:15.607020', 'created_date': '2017-01-06'}