Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4311793641', 'doi': 'https://doi.org/10.3390/vaccines10122146', 'title': 'Heterologous Booster Dose with CORBEVAX following Primary Vaccination with COVISHIELD Enhances Protection against SARS-CoV-2', 'display_name': 'Heterologous Booster Dose with CORBEVAX following Primary Vaccination with COVISHIELD Enhances Protection against SARS-CoV-2', 'publication_year': 2022, 'publication_date': '2022-12-14', 'ids': {'openalex': 'https://openalex.org/W4311793641', 'doi': 'https://doi.org/10.3390/vaccines10122146', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/36560556'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/vaccines10122146', 'pdf_url': 'https://www.mdpi.com/2076-393X/10/12/2146/pdf?version=1671532569', 'source': {'id': 'https://openalex.org/S4210226234', 'display_name': 'Vaccines', 'issn_l': '2076-393X', 'issn': ['2076-393X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.mdpi.com/2076-393X/10/12/2146/pdf?version=1671532569', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5016699982', 'display_name': 'J. Shashidhar', 'orcid': 'https://orcid.org/0000-0001-7318-3942'}, 'institutions': [{'id': 'https://openalex.org/I4210137328', 'display_name': 'Asian Institute of Gastroenterology', 'ror': 'https://ror.org/03pq6f684', 'country_code': 'IN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210137328']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Shashidhar Jaggaiahgari', 'raw_affiliation_strings': ['Institute of Translational Research, Asian Healthcare Foundation, AIG Hospitals, Hyderabad 500032, India'], 'affiliations': [{'raw_affiliation_string': 'Institute of Translational Research, Asian Healthcare Foundation, AIG Hospitals, Hyderabad 500032, India', 'institution_ids': ['https://openalex.org/I4210137328']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5024308542', 'display_name': 'Apoorva Munigela', 'orcid': None}, 'institutions': [], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Apoorva Munigela', 'raw_affiliation_strings': ['Department of Internal Medicine, AIG Hospitals, Hyderabad 500032, India'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine, AIG Hospitals, Hyderabad 500032, India', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042210400', 'display_name': 'Mitnala Sasikala', 'orcid': 'https://orcid.org/0000-0002-3785-0530'}, 'institutions': [{'id': 'https://openalex.org/I4210137328', 'display_name': 'Asian Institute of Gastroenterology', 'ror': 'https://ror.org/03pq6f684', 'country_code': 'IN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210137328']}], 'countries': ['IN'], 'is_corresponding': True, 'raw_author_name': 'Sasikala Mitnala', 'raw_affiliation_strings': ['Institute of Translational Research, Asian Healthcare Foundation, AIG Hospitals, Hyderabad 500032, India'], 'affiliations': [{'raw_affiliation_string': 'Institute of Translational Research, Asian Healthcare Foundation, AIG Hospitals, Hyderabad 500032, India', 'institution_ids': ['https://openalex.org/I4210137328']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034033152', 'display_name': 'Deepika Gujjarlapudi', 'orcid': 'https://orcid.org/0000-0002-1806-725X'}, 'institutions': [], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Deepika Gujjarlapudi', 'raw_affiliation_strings': ['Department of Biochemistry, AIG Hospitals, Hyderabad 500032, India'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, AIG Hospitals, Hyderabad 500032, India', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084759253', 'display_name': 'Venu Simhadri', 'orcid': 'https://orcid.org/0009-0008-7448-1317'}, 'institutions': [{'id': 'https://openalex.org/I4210137328', 'display_name': 'Asian Institute of Gastroenterology', 'ror': 'https://ror.org/03pq6f684', 'country_code': 'IN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210137328']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Venu Simhadri', 'raw_affiliation_strings': ['Institute of Translational Research, Asian Healthcare Foundation, AIG Hospitals, Hyderabad 500032, India'], 'affiliations': [{'raw_affiliation_string': 'Institute of Translational Research, Asian Healthcare Foundation, AIG Hospitals, Hyderabad 500032, India', 'institution_ids': ['https://openalex.org/I4210137328']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5045465005', 'display_name': 'Nageshwar Reddy D', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210137328', 'display_name': 'Asian Institute of Gastroenterology', 'ror': 'https://ror.org/03pq6f684', 'country_code': 'IN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210137328']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Nageshwar Reddy D', 'raw_affiliation_strings': ['Institute of Translational Research, Asian Healthcare Foundation, AIG Hospitals, Hyderabad 500032, India'], 'affiliations': [{'raw_affiliation_string': 'Institute of Translational Research, Asian Healthcare Foundation, AIG Hospitals, Hyderabad 500032, India', 'institution_ids': ['https://openalex.org/I4210137328']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5042210400'], 'corresponding_institution_ids': ['https://openalex.org/I4210137328'], 'apc_list': {'value': 2200, 'currency': 'CHF', 'value_usd': 2382, 'provenance': 'doaj'}, 'apc_paid': {'value': 2200, 'currency': 'CHF', 'value_usd': 2382, 'provenance': 'doaj'}, 'fwci': 0.792, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 6, 'citation_normalized_percentile': {'value': 0.682618, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 85, 'max': 87}, 'biblio': {'volume': '10', 'issue': '12', 'first_page': '2146', 'last_page': '2146'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10118', 'display_name': 'SARS-CoV-2 and COVID-19 Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10118', 'display_name': 'SARS-CoV-2 and COVID-19 Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10041', 'display_name': 'COVID-19 Clinical Research Studies', 'score': 0.996, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10833', 'display_name': 'Vaccine Coverage and Hesitancy', 'score': 0.9888, 'subfield': {'id': 'https://openalex.org/subfields/3306', 'display_name': 'Health'}, 'field': {'id': 'https://openalex.org/fields/33', 'display_name': 'Social Sciences'}, 'domain': {'id': 'https://openalex.org/domains/2', 'display_name': 'Social Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/booster', 'display_name': 'Booster (rocketry)', 'score': 0.9325503}, {'id': 'https://openalex.org/keywords/heterologous', 'display_name': 'Heterologous', 'score': 0.91897273}, {'id': 'https://openalex.org/keywords/booster-dose', 'display_name': 'Booster dose', 'score': 0.8160293}], 'concepts': [{'id': 'https://openalex.org/C203165030', 'wikidata': 'https://www.wikidata.org/wiki/Q741745', 'display_name': 'Booster (rocketry)', 'level': 2, 'score': 0.9325503}, {'id': 'https://openalex.org/C2780115692', 'wikidata': 'https://www.wikidata.org/wiki/Q5747302', 'display_name': 'Heterologous', 'level': 3, 'score': 0.91897273}, {'id': 'https://openalex.org/C12590561', 'wikidata': 'https://www.wikidata.org/wiki/Q2920497', 'display_name': 'Booster dose', 'level': 4, 'score': 0.8160293}, {'id': 'https://openalex.org/C22070199', 'wikidata': 'https://www.wikidata.org/wiki/Q192995', 'display_name': 'Vaccination', 'level': 2, 'score': 0.6961633}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.48738414}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.47599566}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.46732345}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.40413123}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.39740115}, {'id': 'https://openalex.org/C2780801004', 'wikidata': 'https://www.wikidata.org/wiki/Q1415366', 'display_name': 'Immunization', 'level': 3, 'score': 0.27108678}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.12179747}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C1276947', 'wikidata': 'https://www.wikidata.org/wiki/Q333', 'display_name': 'Astronomy', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/vaccines10122146', 'pdf_url': 'https://www.mdpi.com/2076-393X/10/12/2146/pdf?version=1671532569', 'source': {'id': 'https://openalex.org/S4210226234', 'display_name': 'Vaccines', 'issn_l': '2076-393X', 'issn': ['2076-393X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/9f12403052134e0ca4468532b6d69928', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781398', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/36560556', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/vaccines10122146', 'pdf_url': 'https://www.mdpi.com/2076-393X/10/12/2146/pdf?version=1671532569', 'source': {'id': 'https://openalex.org/S4210226234', 'display_name': 'Vaccines', 'issn_l': '2076-393X', 'issn': ['2076-393X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.81, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 34, 'referenced_works': ['https://openalex.org/W1967994686', 'https://openalex.org/W2024524568', 'https://openalex.org/W2996158718', 'https://openalex.org/W3036543467', 'https://openalex.org/W3132713125', 'https://openalex.org/W3160467328', 'https://openalex.org/W3177819637', 'https://openalex.org/W3186217635', 'https://openalex.org/W3188307511', 'https://openalex.org/W3189762432', 'https://openalex.org/W3192494915', 'https://openalex.org/W3208466650', 'https://openalex.org/W3213246152', 'https://openalex.org/W3217262401', 'https://openalex.org/W4200186816', 'https://openalex.org/W4200598759', 'https://openalex.org/W4205761037', 'https://openalex.org/W4206399312', 'https://openalex.org/W4206807722', 'https://openalex.org/W4206932115', 'https://openalex.org/W4207003944', 'https://openalex.org/W4210450230', 'https://openalex.org/W4220917686', 'https://openalex.org/W4223571845', 'https://openalex.org/W4223986041', 'https://openalex.org/W4225014962', 'https://openalex.org/W4225820094', 'https://openalex.org/W4226054307', 'https://openalex.org/W4226271088', 'https://openalex.org/W4226343533', 'https://openalex.org/W4226376477', 'https://openalex.org/W4226396899', 'https://openalex.org/W4286009783', 'https://openalex.org/W4291398405'], 'related_works': ['https://openalex.org/W4387965302', 'https://openalex.org/W4311793641', 'https://openalex.org/W4302774475', 'https://openalex.org/W4292227878', 'https://openalex.org/W4283826450', 'https://openalex.org/W4223961516', 'https://openalex.org/W4207003944', 'https://openalex.org/W4200574689', 'https://openalex.org/W2385876451', 'https://openalex.org/W2324037830'], 'abstract_inverted_index': {'Despite': [0], 'effective': [1], 'vaccination': [2, 61], 'programs,': [3], 'waning': [4], 'immunity': [5], 'in': [6, 85, 109, 118], 'the': [7, 11, 45, 49, 140, 147, 152, 158, 170, 179, 183], 'vaccinated': [8], 'populations': [9], 'and': [10, 36, 44, 71, 91, 129], 'emergence': [12], 'of': [13, 15, 20, 47, 51, 65, 142, 163, 169, 178], 'variants': [14], 'concern': [16], 'posed': [17], 'a': [18, 82, 104, 113, 121], 'risk': [19], 'breakthrough': [21], 'infections.': [22], 'A': [23], 'booster': [24, 56, 79, 98, 115, 123, 149, 172], 'dose': [25], 'was': [26, 144, 173], 'demonstrated': [27], 'to': [28, 40, 107, 120, 151], 'provide': [29], 'substantially': [30], 'increased': [31, 96], 'protection': [32, 156], 'against': [33], 'symptomatic': [34], 'disease': [35], 'hospitalization.': [37], 'We': [38], 'aimed': [39], 'evaluate': [41], 'immune': [42], 'memory': [43, 93, 102, 128], 'efficacy': [46], 'reducing': [48], 'rate': [50, 162], 'SARS-CoV-2': [52, 67], 'infection': [53, 164], 'post': [54], 'heterologous': [55, 88, 122, 148, 159, 171], 'with': [57, 62, 77, 81, 97, 136, 146, 157, 182], 'CORBEVAX': [58], 'after': [59, 167], 'primary': [60], 'two': [63], 'doses': [64], 'COVISHIELD.': [66], 'S1/S2': [68], 'spike': [69], 'IgG': [70], 'RBD-specific': [72, 126], 'antibody': [73], 'responses': [74, 94], 'were': [75, 95, 134], 'elicited': [76], 'both': [78, 137], 'vaccines,': [80], 'greater': [83, 155], 'response': [84, 143], 'individuals': [86, 110], 'receiving': [87], 'booster.': [89, 160], 'T': [90], 'B': [92, 101, 127, 132], 'dose,': [99], 'whereas': [100], 'needed': [103], 'longer': [105, 145], 'duration': [106, 141], 'develop': [108], 'who': [111], 'received': [112], 'homologous': [114, 180], '(90': [116], 'days)': [117], 'comparison': [119], '(30': [124], 'days).': [125], 'antibody-secreting': [130], '(non-memory)': [131], 'lymphocytes': [133], 'enhanced': [135], 'boosters;': [138], 'however,': [139], 'compared': [150], 'homologous,': [153], 'indicating': [154], 'The': [161], '14': [165], 'days': [166], 'administration': [168], 'comparatively': [174], 'lower': [175], 'than': [176], 'that': [177], 'booster,': [181], 'symptoms': [184], 'being': [185], 'much': [186], 'less': [187], 'or': [188], 'asymptomatic.': [189]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4311793641', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 2}], 'updated_date': '2025-01-05T05:51:04.402816', 'created_date': '2022-12-28'}