Title: STUDY ON IMMUNORESPONSIBILITY TO BOOSTER INJECTION OF HBV VACCINATION
Abstract:Eighty seven babies from mothers with positive HBsAg in sera were vaccinated with HBIG and HBV vaccine.When the titer of anti-HBS decreased to below 10(RIA S/N ratio) the booster injection was given d...Eighty seven babies from mothers with positive HBsAg in sera were vaccinated with HBIG and HBV vaccine.When the titer of anti-HBS decreased to below 10(RIA S/N ratio) the booster injection was given during the following up period for 5 years.The level of anti-HBS rerose to more than 10 (RIA S/N ratio) in 39.2% of 166 times of booster injection.The GMT of RIA S/N ratio was from below 10 to 30.8.It was also observed that the immunoresponsibility to booster injection was closely correlated with the primary immunoresponsibility to HBV vaccine.In major of the babies responsed to primary HBV vaccination higher,the titer of anti-HBS after booster injection was higher,the required times of booster injection was fewer,and the effective level of anti-HBS was maintained longer.The study suggested that the status of immunity of organism not only determines the responsibility to the primary HBV vaccination but also determines the immunoresponsibility to the booster injeetion.The method of primary HBV vaccination and the dose of booster injection were not observed to relate to the immunoresponsibility of booster injectionRead More
Publication Year: 1993
Publication Date: 1993-01-01
Language: en
Type: article
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