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'https://openalex.org/W3030045403', 'https://openalex.org/W3029559151', 'https://openalex.org/W3029072200', 'https://openalex.org/W3028824490', 'https://openalex.org/W2385760773', 'https://openalex.org/W2379938528', 'https://openalex.org/W2378416755', 'https://openalex.org/W2365693449', 'https://openalex.org/W2358118032', 'https://openalex.org/W2356048092', 'https://openalex.org/W2355725104', 'https://openalex.org/W2355636150', 'https://openalex.org/W2353510524', 'https://openalex.org/W2353359328', 'https://openalex.org/W2347362682', 'https://openalex.org/W2328486206'], 'abstract_inverted_index': {'目的': [0], '探讨暴露性干眼病大鼠模型结膜上皮细胞凋亡相关基因的表达与组织损伤的关系.方法': [1], '25只健康成年Wistar大鼠随机分为4组实验组和1组正常组.实验结束分别处死每组大鼠,取双眼结膜进行免疫组织化学染色观察结膜组织中凋亡相关基因bax及Bcl-2的表达情况.结果': [2], '各实验组大鼠结膜上皮细胞Bax表达阳性细胞数与正常组相比增加,而Bcl-2阳性表达细胞数较正常组减少,差异均有统计学意义(P<0.05);结膜上皮细胞Bax表达阳性细胞数与暴露时间呈正线性相关(r=0.76,P<0.05),而Bcl-2表达阳性细胞数与暴露时间呈负线性相关(r=-0.78,P<0.05).结论': [3], '暴露性干眼病结膜组织中上皮细胞凋亡可能是导致结膜上皮破坏进而功能丧失的原因之一,bax增加及Bcl-2减少与结膜上皮细胞凋亡有关。': [4]}, 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