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'(H/R)-induced': [10], 'apoptosis': [11, 235], 'in': [12, 28, 181, 222, 236, 254], 'human': [13, 19, 237], 'renal': [14, 20, 238], 'tubular': [15, 21, 239], 'epithelial': [16, 22, 240], 'cells.Methods': [17], 'The': [18], 'cells': [23, 44, 88], 'were': [24, 45, 89, 99, 127, 159, 169, 200, 210], 'cultured': [25], 'and': [26, 63, 74, 86, 95, 118, 123, 137, 156, 165, 177, 184, 197, 206, 218, 247], 'seeded': [27], 'culture': [29, 84], 'dishes': [30], '(2': [31], 'ml/dish)': [32], 'or': [33], '96-well': [34], 'plates': [35], '(200': [36], 'μl/well)': [37], 'with': [38, 150, 191], 'density': [40], '1': [42], '×106/ml.The': [43], 'then': [46, 100], 'randomly': [47], 'divided': [48], 'into': [49], '4': [50], 'groups': [51, 72, 182], '(n': [52], '=30': [53], 'each):normal': [54], 'control': [55], 'group': [56, 59, 62, 67, 151, 192, 223], '(group': [57, 60], 'C),berberine': [58], 'B),H/R': [61], 'H/R': [64, 75, 94, 96, 183, 185, 224], '+': [65, 69, 76, 97, 186, 225], '(H/R': [68], 'B': [70, 73, 98, 187, 226], 'group).In': [71], 'B,berberine': [77], '10': [78], 'μmol/L': [79], 'was': [80, 142, 147, 179, 220], 'added': [81], 'to': [82, 102], 'medium': [85], 'incubated': [90], 'for': [91, 107], '2': [92], 'h.Groups': [93], 'exposed': [101], '94％': [103], 'N2-5％': [104], 'CO2-1％': [105], 'O2': [106], '24': [108], 'h': [109, 113], 'followed': [110], 'by': [111], '3': [112], 'reoxygenation.The': [114], 'cell': [115, 153, 194], 'viability,apoptotic': [116], 'rate': [117], 'level': [119], 'malondialdehyde': [121], '(MDA)': [122], 'superoxide': [124], 'dismutase': [125], '(SOD)': [126], 'detected.The': [128], 'expression': [129, 158, 172, 199, 213], 'caspase-3,activated': [131], 'caspase-3,cytochrome': [132, 175, 216], 'c,glucose-regulated': [133], 'protein': [134, 140], '78': [135], '(GRP78)': [136], 'C/EBP': [138], 'homologous': [139], '(CHOP)': [141], 'determined.The': [143], 'ratio': [144, 164, 205], 'Bax/Bcl-2': [146], 'calculated.Results': [148], 'Compared': [149], 'C,the': [152], 'viability,SOD': [154, 195], 'activity': [155, 196], 'caspase-3': [157, 198], 'significantly': [160, 201], 'decreased,the': [161], 'apoptotic': [162, 203], 'rate,Bax/Bcl-2': [163, 204], 'concentration': [166, 207], 'MDA': [168, 209], 'increased,and': [170], 'activated': [174, 215], 'c,GRP78': [176, 217], 'CHOP': [178, 219], 'up-regulated': [180], '(P': [188, 227], '＜': [189, 228], '0.05).Compared': [190], 'H/R,the': [193], 'increased,the': [202], 'decreased,and': [211], 'down-regulated': [221], '0.05).Conclusion': [229], 'Berberine': [230], 'can': [232], 'inhibit': [233], 'H/R-induced': [234], 'cells,and': [241], 'inhibition': [242], 'mitochondrial': [244], 'stress': [245, 250], 'pathway': [246, 251], 'endoplasmic': [248], 'reticulum': [249], 'is': [252], 'involved': [253], 'mechanism.\r\n\r\nKey': [256], 'words:': [257], '\r\nBerberine;\xa0': [258], 'Apoptosis;\xa0': [259], 'Oxygen;\xa0': [260], 'Cell': [261], 'hypoxia;\xa0': [262], 'Epithelial': [263], 'cells;\xa0': [264], 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