Title: Comprehensive characterization of the human proteome by multi-omic analyses
Abstract:Global and quantitative analysis of human proteome in different human tissues will provide valuable insights into human biology and disease. In this work, deep proteomes of 29 healthy human tissues we...Global and quantitative analysis of human proteome in different human tissues will provide valuable insights into human biology and disease. In this work, deep proteomes of 29 healthy human tissues were generated using high-resolution mass spectrometry. Integrated analysis with matched transcriptomes revealed unprecedented insights into proteome complexity, relationship between protein and mRNA levels, and protein expression regulation. In addition, proteogemomic analysis were conducted to discover protein evidence of novel protein coding regions and genetic variants.Read More
Publication Year: 2018
Publication Date: 2018-01-01
Language: en
Type: article
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