Publication Information

{'id': 'https://openalex.org/W2885450922', 'doi': None, 'title': 'Abstract 278: Enhanced Cystathionine ß-Synthase Nitration in Diet-Induced Hyperhomocysteinemic Rats Accelerates the Progression of Hyperhomocysteinemia', 'display_name': 'Abstract 278: Enhanced Cystathionine ß-Synthase Nitration in Diet-Induced Hyperhomocysteinemic Rats Accelerates the Progression of Hyperhomocysteinemia', 'publication_year': 2014, 'publication_date': '2014-05-01', 'ids': {'openalex': 'https://openalex.org/W2885450922', 'mag': '2885450922'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://www.ahajournals.org/doi/abs/10.1161/atvb.34.suppl_1.278?related-urls=yesl34%2FSuppl_1%2FA278', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S3485792', 'display_name': 'Arteriosclerosis Thrombosis and Vascular Biology', 'issn_l': '1079-5642', 'issn': ['1079-5642', '1524-4636'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5049184385', 'display_name': 'WenWang', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'WenWang', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109494755', 'display_name': 'HuiZhang', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'HuiZhang', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000017398', 'display_name': 'WeiLiu', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'WeiLiu', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5096055873', 'display_name': 'TengLiu', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'TengLiu', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5024363603', 'display_name': 'QiSun', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'QiSun', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038855946', 'display_name': 'KeWang', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'KeWang', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5001420037', 'display_name': 'Hui-rongLiu', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Hui-rongLiu', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 66}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10499', 'display_name': 'Folate and B Vitamins Research', 'score': 0.9959, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10499', 'display_name': 'Folate and B Vitamins Research', 'score': 0.9959, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11027', 'display_name': 'Metabolism and Genetic Disorders', 'score': 0.9669, 'subfield': {'id': 'https://openalex.org/subfields/1308', 'display_name': 'Clinical Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hyperhomocysteinemia', 'display_name': 'Hyperhomocysteinemia', 'score': 0.9704758}, {'id': 'https://openalex.org/keywords/transsulfuration', 'display_name': 'Transsulfuration', 'score': 0.809041}, {'id': 'https://openalex.org/keywords/methionine-synthase', 'display_name': 'Methionine synthase', 'score': 0.67482}, {'id': 'https://openalex.org/keywords/homocystinuria', 'display_name': 'Homocystinuria', 'score': 0.56917787}], 'concepts': [{'id': 'https://openalex.org/C2776523773', 'wikidata': 'https://www.wikidata.org/wiki/Q1093815', 'display_name': 'Hyperhomocysteinemia', 'level': 3, 'score': 0.9704758}, {'id': 'https://openalex.org/C16525657', 'wikidata': 'https://www.wikidata.org/wiki/Q5201183', 'display_name': 'Cystathionine beta synthase', 'level': 4, 'score': 0.95755017}, {'id': 'https://openalex.org/C2777090595', 'wikidata': 'https://www.wikidata.org/wiki/Q192466', 'display_name': 'Homocysteine', 'level': 2, 'score': 0.931229}, {'id': 'https://openalex.org/C2910648213', 'wikidata': 'https://www.wikidata.org/wiki/Q7835367', 'display_name': 'Transsulfuration', 'level': 5, 'score': 0.809041}, {'id': 'https://openalex.org/C2780912031', 'wikidata': 'https://www.wikidata.org/wiki/Q180341', 'display_name': 'Methionine', 'level': 3, 'score': 0.7307134}, {'id': 'https://openalex.org/C80315684', 'wikidata': 'https://www.wikidata.org/wiki/Q2737583', 'display_name': 'Methionine synthase', 'level': 4, 'score': 0.67482}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.6165569}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.57287866}, {'id': 'https://openalex.org/C2779375456', 'wikidata': 'https://www.wikidata.org/wiki/Q994859', 'display_name': 'Homocystinuria', 'level': 4, 'score': 0.56917787}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.56660926}, {'id': 'https://openalex.org/C2778784160', 'wikidata': 'https://www.wikidata.org/wiki/Q419130', 'display_name': 'Peroxynitrite', 'level': 4, 'score': 0.553748}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.42335698}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.39822954}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.2257443}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.17283359}, {'id': 'https://openalex.org/C515207424', 'wikidata': 'https://www.wikidata.org/wiki/Q8066', 'display_name': 'Amino acid', 'level': 2, 'score': 0.053841174}, {'id': 'https://openalex.org/C2780795997', 'wikidata': 'https://www.wikidata.org/wiki/Q413283', 'display_name': 'Superoxide', 'level': 3, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://www.ahajournals.org/doi/abs/10.1161/atvb.34.suppl_1.278?related-urls=yesl34%2FSuppl_1%2FA278', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S3485792', 'display_name': 'Arteriosclerosis Thrombosis and Vascular Biology', 'issn_l': '1079-5642', 'issn': ['1079-5642', '1524-4636'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.71, 'display_name': 'Zero hunger', 'id': 'https://metadata.un.org/sdg/2'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3177166346', 'https://openalex.org/W3140859978', 'https://openalex.org/W2766557566', 'https://openalex.org/W2471386584', 'https://openalex.org/W2419028341', 'https://openalex.org/W2401495464', 'https://openalex.org/W2305681860', 'https://openalex.org/W2290591681', 'https://openalex.org/W2181451653', 'https://openalex.org/W2151499688', 'https://openalex.org/W2137387976', 'https://openalex.org/W2118747443', 'https://openalex.org/W2107720387', 'https://openalex.org/W2068564411', 'https://openalex.org/W2065170506', 'https://openalex.org/W2062023215', 'https://openalex.org/W2052869577', 'https://openalex.org/W1993547773', 'https://openalex.org/W1874911532', 'https://openalex.org/W1756117989'], 'abstract_inverted_index': {'Hyperhomocysteinemia': [0], 'is': [1, 36, 49, 99], 'an': [2], 'independent': [3], 'risk': [4], 'factor': [5], 'for': [6, 18], 'cardiovascular': [7, 70], 'diseases,which': [8], 'may': [9], 'be': [10], 'caused': [11], 'by': [12], 'genetic': [13], 'deficiencies': [14, 25], 'in': [15, 26, 41, 51, 65, 75, 78], 'enzymes': [16], 'responsible': [17], 'remethylation': [19], 'or': [20, 28], 'transsulfuration': [21, 34], 'of': [22, 31, 54, 81, 89, 94, 108, 129], 'homocysteine,': [23], 'nutritional': [24], 'vitamins,': [27], 'excessive': [29], 'intakes': [30], 'methionine.': [32], 'Since': [33], 'pathway': [35, 40], 'the': [37, 87, 127], 'only': [38], 'irreversible': [39], 'homocysteine': [42], 'metabolism,': [43], 'its': [44], 'key': [45], 'enzyme': [46], 'cystathionine': [47, 82, 102], 'β-synthase': [48], 'vital': [50], 'terminal': [52], 'removement': [53], 'homocysteine.': [55], 'In': [56], 'addition,': [57], 'Studies': [58], 'have': [59], 'observed': [60], 'that': [61], 'enhanced': [62], 'nitrative': [63, 90, 130], 'stress': [64, 91, 131], 'hyperhomocysteinemic': [66], 'rats': [67, 109], 'could': [68], 'induce': [69], 'injuries,': [71], 'and': [72, 96], 'peroxynitrite': [73], 'stimulation': [74], 'vitro': [76], 'resulting': [77], 'decreased': [79], 'bioactivity': [80], 'β-synthase.': [83], 'Therefore,': [84], 'to': [85, 92, 101, 125], 'determine': [86], 'contribution': [88], 'progression': [93], 'hyperhomocysteinemia,': [95], 'how': [97], 'it': [98], 'related': [100], 'β-synthase,': [103], 'we': [104], 'used': [105], 'three': [106], 'groups': [107], '(Con': [110], 'with': [111, 115, 120], 'normal': [112], 'diet,': [113, 118], 'HHcy': [114], '2.5%': [116, 121], 'methionine': [117, 122], 'HHcy+FeTMPyP': [119], 'diet': [123], '+FeTMPyP)': [124], 'observe': [126], 'effects': [128], '...': [132]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2885450922', 'counts_by_year': [], 'updated_date': '2024-12-07T06:25:23.760293', 'created_date': '2018-08-22'}