Publication Information

{'id': 'https://openalex.org/W2151499688', 'doi': 'https://doi.org/10.1161/01.res.0000089561.87997.cf', 'title': 'Homocysteine, a Proinflammatory and Proatherosclerotic Factor', 'display_name': 'Homocysteine, a Proinflammatory and Proatherosclerotic Factor', 'publication_year': 2003, 'publication_date': '2003-08-21', 'ids': {'openalex': 'https://openalex.org/W2151499688', 'doi': 'https://doi.org/10.1161/01.res.0000089561.87997.cf', 'mag': '2151499688', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/12933697'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1161/01.res.0000089561.87997.cf', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S10652568', 'display_name': 'Circulation Research', 'issn_l': '0009-7330', 'issn': ['0009-7330', '1524-4571'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'letter', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': 'https://doi.org/10.1161/01.res.0000089561.87997.cf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5068617049', 'display_name': 'Valérie B. Schini–Kerth', 'orcid': 'https://orcid.org/0000-0001-9997-9287'}, 'institutions': [{'id': 'https://openalex.org/I68947357', 'display_name': 'Université de Strasbourg', 'ror': 'https://ror.org/00pg6eq24', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I68947357']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}], 'countries': ['FR'], 'is_corresponding': True, 'raw_author_name': 'Valérie B. Schini-Kerth', 'raw_affiliation_strings': ['From the UMR CNRS 7034, University Louis Pasteur Strasbourg, Faculty of Pharmacy, Illkirch, France.'], 'affiliations': [{'raw_affiliation_string': 'From the UMR CNRS 7034, University Louis Pasteur Strasbourg, Faculty of Pharmacy, Illkirch, France.', 'institution_ids': ['https://openalex.org/I68947357', 'https://openalex.org/I1294671590']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5068617049'], 'corresponding_institution_ids': ['https://openalex.org/I68947357', 'https://openalex.org/I1294671590'], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 19, 'citation_normalized_percentile': {'value': 0.870504, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 85, 'max': 86}, 'biblio': {'volume': '93', 'issue': '4', 'first_page': '271', 'last_page': '273'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10499', 'display_name': 'Folate and B Vitamins Research', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10499', 'display_name': 'Folate and B Vitamins Research', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13657', 'display_name': 'Aortic Thrombus and Embolism', 'score': 0.9936, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11964', 'display_name': 'Pregnancy and Medication Impact', 'score': 0.9862, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/proinflammatory-cytokine', 'display_name': 'Proinflammatory cytokine', 'score': 0.82304883}, {'id': 'https://openalex.org/keywords/factor', 'display_name': 'Factor (programming language)', 'score': 0.41826478}], 'concepts': [{'id': 'https://openalex.org/C164027704', 'wikidata': 'https://www.wikidata.org/wiki/Q3491837', 'display_name': 'Proinflammatory cytokine', 'level': 3, 'score': 0.82304883}, {'id': 'https://openalex.org/C2777090595', 'wikidata': 'https://www.wikidata.org/wiki/Q192466', 'display_name': 'Homocysteine', 'level': 2, 'score': 0.5958835}, {'id': 'https://openalex.org/C2781039887', 'wikidata': 'https://www.wikidata.org/wiki/Q1391724', 'display_name': 'Factor (programming language)', 'level': 2, 'score': 0.41826478}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.31285775}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.30538917}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.23882005}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.23491156}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.21736673}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.19853157}, {'id': 'https://openalex.org/C199360897', 'wikidata': 'https://www.wikidata.org/wiki/Q9143', 'display_name': 'Programming language', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D006710', 'descriptor_name': 'Homocysteine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D001161', 'descriptor_name': 'Arteriosclerosis', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001161', 'descriptor_name': 'Arteriosclerosis', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D001161', 'descriptor_name': 'Arteriosclerosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006710', 'descriptor_name': 'Homocysteine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006710', 'descriptor_name': 'Homocysteine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D009000', 'descriptor_name': 'Monocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009000', 'descriptor_name': 'Monocytes', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D009000', 'descriptor_name': 'Monocytes', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D009000', 'descriptor_name': 'Monocytes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D017382', 'descriptor_name': 'Reactive Oxygen Species', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017382', 'descriptor_name': 'Reactive Oxygen Species', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1161/01.res.0000089561.87997.cf', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S10652568', 'display_name': 'Circulation Research', 'issn_l': '0009-7330', 'issn': ['0009-7330', '1524-4571'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12933697', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1161/01.res.0000089561.87997.cf', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S10652568', 'display_name': 'Circulation Research', 'issn_l': '0009-7330', 'issn': ['0009-7330', '1524-4571'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 18, 'referenced_works': ['https://openalex.org/W1928375173', 'https://openalex.org/W1975357252', 'https://openalex.org/W1991720779', 'https://openalex.org/W1995130186', 'https://openalex.org/W2026890956', 'https://openalex.org/W2087226015', 'https://openalex.org/W2104985991', 'https://openalex.org/W2108484297', 'https://openalex.org/W2108730399', 'https://openalex.org/W2118233199', 'https://openalex.org/W2118540570', 'https://openalex.org/W2123799914', 'https://openalex.org/W2151482800', 'https://openalex.org/W2164721380', 'https://openalex.org/W2316286258', 'https://openalex.org/W2323783182', 'https://openalex.org/W4324114529', 'https://openalex.org/W90081202'], 'related_works': ['https://openalex.org/W3032375762', 'https://openalex.org/W3031052312', 'https://openalex.org/W2899084033', 'https://openalex.org/W2748952813', 'https://openalex.org/W2595654912', 'https://openalex.org/W219653125', 'https://openalex.org/W2183966825', 'https://openalex.org/W2167100109', 'https://openalex.org/W2080531066', 'https://openalex.org/W1995515455'], 'abstract_inverted_index': {'HomeCirculation': [0], 'ResearchVol.': [1], '93,': [2, 2163], 'No.': [3], '4Homocysteine,': [4], 'a': [5, 25, 75, 88, 274, 383, 388, 468, 516, 569, 654, 793, 868, 890, 942, 955, 959, 973, 982, 1008, 1148, 1379, 1467, 1593, 1646, 2021], 'Proinflammatory': [6, 26], 'and': [7, 27, 71, 84, 127, 149, 176, 185, 244, 305, 426, 439, 457, 460, 479, 488, 527, 566, 597, 606, 631, 638, 660, 678, 681, 708, 722, 726, 744, 753, 763, 784, 853, 881, 915, 950, 966, 1000, 1014, 1074, 1087, 1119, 1139, 1145, 1177, 1189, 1195, 1214, 1354, 1399, 1434, 1439, 1443, 1447, 1492, 1498, 1522, 1528, 1583, 1642, 1675, 1704, 1730, 1762, 1768, 1800, 1830, 1840, 1849, 1884, 1893, 1925, 1941, 1969, 2006, 2014, 2028, 2052, 2074, 2099, 2138, 2143], 'Proatherosclerotic': [8, 28], 'Factor': [9], 'Free': [10], 'AccessEditorialPDF/EPUBAboutView': [11], 'PDFView': [12], 'EPUBSections': [13], 'ToolsAdd': [14], 'to': [15, 87, 111, 166, 219, 269, 282, 294, 303, 319, 345, 361, 402, 418, 423, 482, 537, 552, 724, 818, 840, 920, 941, 980, 1037, 1069, 1097, 1100, 1103, 1121, 1127, 1163, 1241, 1262, 1289, 1813, 2151], 'favoritesDownload': [16], 'citationsTrack': [17], 'citationsPermissions': [18], 'ShareShare': [19], 'onFacebookTwitterLinked': [20], 'InMendeleyReddit': [21], 'Jump': [22], 'toFree': [23], 'AccessEditorialPDF/EPUBHomocysteine,': [24], 'FactorRole': [29], 'of': [30, 53, 69, 80, 92, 98, 113, 135, 157, 163, 173, 181, 199, 331, 348, 354, 358, 365, 377, 397, 407, 436, 452, 470, 477, 518, 525, 548, 555, 562, 571, 582, 599, 629, 648, 657, 674, 706, 720, 732, 748, 756, 761, 770, 779, 796, 803, 809, 835, 844, 860, 864, 892, 910, 927, 934, 948, 954, 988, 997, 1003, 1029, 1042, 1054, 1067, 1078, 1085, 1092, 1108, 1124, 1131, 1157, 1175, 1184, 1191, 1203, 1211, 1219, 1239, 1243, 1252, 1265, 1269, 1280, 1284, 1295, 1334, 1340, 1375, 1431, 1494, 1524, 1672, 1706, 1788, 1895, 1902, 1938, 1945, 2023, 2071, 2080, 2114, 2147], 'Intracellular': [31, 1550], 'Reactive': [32], 'Oxygen': [33], 'Species': [34], 'Valérie': [35, 38, 1290], 'B.': [36, 39, 41, 1291, 1786], 'Schini-Kerth': [37, 42], 'Schini-KerthValérie': [40], 'From': [43], 'the': [44, 67, 114, 161, 179, 196, 247, 260, 296, 308, 313, 342, 346, 362, 374, 434, 443, 450, 462, 495, 505, 511, 540, 553, 580, 595, 627, 671, 704, 711, 717, 768, 771, 776, 800, 810, 823, 832, 841, 857, 861, 872, 882, 911, 928, 932, 935, 946, 967, 986, 991, 1001, 1020, 1024, 1035, 1043, 1050, 1064, 1082, 1105, 1122, 1129, 1164, 1173, 1187, 1209, 1217, 1220, 1248, 1263, 1266, 1281, 1285, 1338, 1670, 1702, 1802, 1891, 2148], 'UMR': [45, 1305], 'CNRS': [46, 1306], '7034,': [47, 1307], 'University': [48], 'Louis': [49, 1309], 'Pasteur': [50, 1310], 'Strasbourg,': [51, 1312], 'Faculty': [52], 'Pharmacy,': [54], 'Illkirch,': [55, 1323], 'France.': [56, 1324], 'Originally': [57, 2171], 'published22': [58], 'Aug': [59], '2003https://doi.org/10.1161/01.RES.0000089561.87997.CFCirculation': [60], 'Research.': [61], '2003;93:271–273In': [62], '1969,': [63], 'McCully': [64, 1330], 'first': [65, 228], 'described': [66], 'association': [68, 1835], 'hyperhomocysteinemia': [70, 431, 491, 532, 697, 1232], 'vascular': [72, 121, 538, 642, 739, 1244, 1383, 1472, 1537, 1589], 'disease': [73, 122, 557, 1898], 'in': [74, 82, 108, 256, 289, 307, 325, 327, 382, 442, 461, 480, 504, 508, 522, 579, 585, 615, 633, 640, 663, 683, 710, 758, 787, 799, 985, 1116, 1141, 1147, 1167, 1197, 1260, 1273, 1437, 1450, 1500, 1530, 1561, 1588, 1617, 1678, 1708, 1727, 1773, 1796, 1844, 1890, 1981, 2020, 2061, 2065, 2068, 2107], 'patient': [76], 'with': [77, 120, 390, 587, 906, 1445], 'elevated': [78, 154, 545], 'levels': [79, 134, 357, 406, 547], 'homocysteine': [81, 93, 136, 158, 212, 315, 340, 355, 359, 372, 378, 398, 408, 453, 509, 529, 549, 593, 625, 675, 780, 804, 819, 836, 965, 1185, 1204, 1377, 1433, 1560], 'plasma': [83, 133, 155, 395, 526, 546, 1376], 'urine': [85, 528], 'due': [86, 839, 1099], 'rare': [89, 493], 'genetic': [90, 502], 'deficiency': [91, 517], 'metabolism.1': [94], 'A': [95, 1372, 1940, 2008], 'large': [96], 'number': [97], 'clinical': [99, 150, 573], 'studies': [100, 1118], 'have': [101, 1113, 1645], 'indicated': [102, 653], 'that': [103, 153, 235, 575, 592, 624, 670, 1026, 1052, 1180, 1230], 'mild': [104, 696, 1231], 'hyperhomocysteinemia,': [105], 'which': [106, 170, 253, 278, 328, 446, 544, 977], 'occurs': [107, 254], 'approximately': [109], '5%': [110], '7%': [112], 'general': [115, 496], 'population,': [116], 'is': [117, 188, 213, 279, 316, 333, 338, 368, 379, 492, 499, 686, 900, 972, 978, 1049, 1205], 'also': [118, 266, 668, 765, 1161], 'associated': [119], 'including': [123, 849], 'coronary': [124], 'artery,': [125], 'cerebrovascular,': [126], 'peripheral': [128], 'arterial': [129, 713], 'occlusive': [130, 182, 1471], 'diseases.2,3': [131], 'Elevated': [132, 405], 'are': [137, 171, 410, 447, 550, 1276], 'considered': [138], 'as': [139, 240, 246, 387, 412, 465, 467, 690, 692, 820, 1137, 1378, 1466], 'an': [140, 189, 201, 233, 241, 329, 700, 1155], 'independent': [141], 'risk': [142, 1380, 1468], 'factor': [143, 813, 1381, 1469, 1580], 'for': [144, 449, 612, 703, 871, 1010, 1337, 1382, 1470, 1536, 1596, 1649, 1756], 'atherothrombotic': [145, 556], 'disease.4': [146], 'Both': [147], 'experimental': [148, 1227], 'data': [151], 'suggest': [152], 'concentrations': [156, 396, 409, 689, 1183, 1449], 'might': [159, 576, 698, 1061, 1160, 1233, 1255], 'accelerate': [160], 'development': [162], 'atherosclerotic': [164, 168, 583, 650, 1638], 'lesions': [165, 584], 'advanced': [167], 'plaques,': [169], 'sites': [172, 1242], 'endothelial': [174, 636, 736, 1143, 1169, 1533, 1562, 1673, 1775, 2059], 'erosion': [175], 'rupture': [177], 'triggering': [178], 'formation': [180, 347, 843, 1107, 1210], 'mural': [183], 'thrombi': [184], 'ischemic': [186], 'events.Homocysteine': [187], 'intermediate': [190, 421], 'sulfur-containing': [191], 'amino': [192, 203], 'acid': [193, 204], 'formed': [194, 314], 'during': [195], 'intracellular': [197, 842, 1106, 1212], 'metabolism': [198, 451], 'methionine,': [200], 'essential': [202, 242], 'supplied': [205], 'by': [206, 223, 271, 285, 321, 501, 543, 822, 831, 964, 1019, 1045, 1236, 1559, 1793], 'dietary': [207], 'proteins': [208], '(see': [209, 350], 'Figure).2': [210], 'Once': [211], 'formed,': [214], 'it': [215], 'may': [216, 265, 1215, 1644], 'be': [217, 267, 292, 300, 433, 577, 895, 921, 1098, 1256], 'recycled': [218], 'methionine': [220, 231, 320, 322, 332], 'after': [221], 'remethylation': [222], 'two': [224, 609, 907, 1031, 1076], 'different': [225], 'pathways.': [226], 'The': [227, 250, 589, 665, 815, 1089, 1200, 1754, 2077], 'one': [229], 'involves': [230, 259], 'synthase,': [232, 323], 'enzyme': [234, 261], 'uses': [236], 'vitamin': [237, 275, 444, 455, 458, 1837], 'B12': [238, 456, 1838], '(cobalamin)': [239], 'cofactor': [243], 'N5-methyl-tetrahydrofolate': [245], 'methyl': [248], 'donor.': [249], 'second': [251], 'pathway,': [252], 'exclusively': [255], 'hepatic': [257, 1709], 'tissue,': [258], 'betaine-homocysteine': [262], 'methyltransferase.': [263], 'Homocysteine': [264, 1353, 1398, 1489, 1519, 1577, 1700, 1929, 2012, 2103], 'converted': [268], 'cystathionine': [270, 272, 286, 519], 'β-synthase,': [273, 520], 'B6-dependent': [276], 'enzyme,': [277, 976], 'subsequently': [280], 'hydrolyzed': [281], 'form': [283, 385], 'cysteine': [284, 336, 349], 'γ-lyase.': [287], 'Cysteine,': [288], 'turn,': [290], 'can': [291, 432], 'used': [293], 'synthesize': [295], 'antioxidant': [297], 'glutathione': [298], 'or': [299, 335, 386, 392, 931, 1283], 'further': [301], 'metabolized': [302], 'sulfate': [304], 'excreted': [306], 'urine.': [309], 'Under': [310], 'physiological': [311], 'conditions,': [312], 'predominantly': [317, 662], 'remethylated': [318], 'whereas': [324, 875], 'conditions': [326], 'excess': [330], 'present,': [334], 'synthesis': [337, 755], 'required,': [339], 'enters': [341], 'pathway': [343], 'leading': [344], 'Figure).2Download': [351], 'figureDownload': [352], 'PowerPointSchematic': [353], 'metabolism.Plasma': [356], 'refer': [360], 'total': [363, 1432], 'pool': [364], 'homocysteine.': [366, 1070], 'There': [367], 'very': [369], 'little': [370], 'free': [371], 'since': [373, 897], 'vast': [375], 'majority': [376], 'present': [380, 568, 666], 'either': [381], 'protein-bound': [384], 'dimer': [389], 'itself': [391], 'cysteine.': [393], 'Physiological': [394], 'range': [399], 'from': [400, 416, 1636], '5': [401], '15': [403], 'μmol/L.5': [404], 'categorized': [411], 'moderate': [413], '(concentrations': [414], 'ranging': [415], '16': [417], '30': [419], 'μmol/L),': [420, 425], '(31': [422], '100': [424], 'severe': [427], '(>100': [428], 'μmol/L).6': [429], 'Mild': [430], 'consequence': [435, 469], 'age,': [437], 'gender,': [438], 'nutritional': [440], 'deficiencies': [441], 'cofactors,': [445], 'required': [448], '(including': [454], 'B6,': [459], 'cosubstrate': [463], 'folate),': [464], 'well': [466], 'smoking,': [471], 'renal': [472], 'disease,': [473, 539], 'hypothyroidism,': [474], 'several': [475], 'types': [476], 'cancer,': [478], 'response': [481, 817, 962, 1036, 1066, 1677], 'drugs': [483], 'like': [484], 'methotrexate,': [485], 'phenytoin,': [486], 'cyclosporine,': [487], 'metformin.': [489], 'Severe': [490], 'among': [494], 'population.': [497], 'It': [498, 918], 'caused': [500], 'defects': [503], 'enzymes': [506], 'involved': [507, 578], 'metabolism,': [510], 'most': [512, 805], 'common': [513], 'disorder': [514], 'being': [515], 'resulting': [521], 'marked': [523], 'elevations': [524], 'concentrations.': [530], 'Although': [531, 990], 'has': [533, 652, 866, 1016], 'been': [534, 1017, 1114], 'linked': [535, 1120], 'clinically': [536], 'molecular': [541, 992], 'mechanism': [542, 570, 993], 'related': [551], 'pathogenesis': [554, 987, 1339, 1892], 'remains': [558, 919, 1006], 'unclear.In': [559], 'this': [560, 898, 1274], 'issue': [561], 'Circulation': [563, 1984], 'Research,': [564, 1985], 'Zeng': [565, 762, 949, 1046, 1176, 1481], 'colleagues7': [567, 764, 1178], 'potential': [572, 1249], 'importance': [574], 'progression': [581], 'patients': [586], 'hyperhomocysteinemia.': [588], 'authors': [590, 1021], 'report': [591], 'stimulates': [594, 1578, 1701], 'expression': [596, 628, 656, 680, 786, 1130, 1188, 1491, 1521, 1557, 1587], 'secretion': [598, 682, 1190, 1493, 1523, 1705], 'biologically': [600, 1192], 'active': [601, 1193], 'monocyte': [602, 1150, 1495, 1525, 1554, 1584], 'chemoattractant': [603, 1496, 1526, 1555, 1585, 1615, 2176], 'protein-1': [604, 1497, 1527, 1556, 1586, 1616], '(MCP-1)': [605], 'interleukin-8': [607, 1499, 1529], '(IL-8),': [608], 'major': [610, 869, 983, 1132], 'chemokines': [611], 'leukocyte': [613], 'trafficking,': [614], 'human': [616, 634, 641, 649, 684, 788, 998, 1142, 1149, 1168, 1198, 1501, 1531, 1618, 1637], 'monocytes.': [617, 789, 1199, 1502], 'These': [618, 790], 'findings': [619, 904, 1025], 'extend': [620], 'previous': [621, 1117], 'ones': [622], 'indicating': [623], 'induces': [626, 1520, 1930], 'MCP-1': [630, 639, 659, 677, 707, 783, 1086, 1194], 'IL-8': [632, 679, 709, 785, 1196, 1650], 'aortic': [635, 1532, 2109], 'cells8,9': [637], 'smooth': [643, 740, 1590, 1931, 2110], 'muscle': [644, 741, 1591, 1932, 2111], 'cells.10': [645], 'Moreover,': [646, 856], 'examination': [647], 'plaques': [651, 1639], 'pronounced': [655], 'both': [658, 782, 1072, 1093], 'IL-8,': [661, 1641], 'macrophages.11,12': [664], 'study': [667, 1224], 'indicates': [669], 'stimulatory': [672, 777, 801, 1201], 'effect': [673, 778, 802, 1091, 1166, 1202, 1251, 1268, 2070], 'on': [676, 767, 781, 903, 1023, 1208, 2011], 'monocytes': [685, 999, 1068], 'observed': [687], 'at': [688, 1258], 'low': [691], '10': [693], 'μmol/L.': [694], 'Thus,': [695], 'provide': [699, 952], 'efficient': [701], 'stimulus': [702], 'accumulation': [705, 719], 'injured': [712], 'wall,': [714], 'thereby': [715], 'promoting': [716], 'localized': [718], 'macrophages': [721], 'contributing': [723], 'proinflammatory': [725, 2075], 'proatherosclerotic': [727], 'responses.': [728], 'Other': [729], 'plausible': [730], 'mechanisms': [731], 'homocysteine-induced': [733, 995, 1083], 'atherosclerosis': [734], 'include': [735], 'dysfunction,': [737], 'increased': [738, 754], 'cell': [742, 1151, 1933], 'proliferation': [743, 1934], 'platelet': [745, 1676], 'activation,': [746], 'promotion': [747], 'lipoprotein': [749], 'oxidation,': [750], 'enhanced': [751], 'coagulability,': [752], 'cholesterol': [757, 1707], 'hepatocytes.13,14The': [759], 'work': [760, 1174], 'focused': [766], 'characterization': [769, 859], 'signal': [772], 'transduction': [773], 'pathway(s)': [774], 'mediating': [775], 'investigations': [791], 'indicate': [792], 'determinant': [794], 'role': [795, 870, 984, 1009, 1595, 1671, 1726], 'oxidative': [797, 2072], 'stress': [798, 2073], 'likely': [806], 'via': [807], 'activation': [808, 996, 1218], 'redox-sensitive': [811, 824, 960], 'transcription': [812], 'NF-κB.': [814], 'pro-oxidant': [816], 'assessed': [821], 'fluorescent': [825], 'probe': [826], 'dichlorofluorescein': [827], 'was': [828], 'not': [829, 887, 1277, 2064], 'explained': [830], 'extracellular': [833], 'auto-oxidation': [834], 'but': [837, 2063], 'rather': [838], 'reactive': [845], 'oxygen': [846, 2179], 'species': [847], '(ROS)': [848], 'superoxide,': [850], 'hydrogen': [851], 'peroxide,': [852], 'hydroxyl': [854], 'radicals.': [855], 'pharmacological': [858, 1027], 'enzymatic': [862], 'source': [863], 'ROS': [865, 1004, 1213], 'suggested': [867, 1018], 'NAD(P)H': [873, 912, 929, 968, 970, 1133, 1221, 1724], 'oxidase': [874, 930, 971, 1134], 'xanthine': [876], 'oxidase,': [877, 913], 'arachidonic': [878], 'acid–metabolizing': [879], 'enzymes,': [880], 'mitochondrial': [883], 'respiratory': [884, 1803], 'chain': [885], 'were': [886], 'involved.': [888], 'However,': [889], 'word': [891], 'caution': [893], 'should': [894], 'spoken,': [896], 'conclusion': [899], 'reached': [901], 'solely': [902], 'obtained': [905], 'unselective': [908], 'inhibitors': [909, 926], 'diphenyleneiodonium': [914], 'phenylarsine': [916], 'oxide.': [917], 'determined': [922], 'whether': [923], 'more': [924], 'selective': [925], 'use': [933], 'p22phox': [936, 1138, 1770], 'antisense': [937], 'approach': [938], 'will': [939], 'lead': [940], 'similar': [943], 'conclusion.': [944], 'Nevertheless,': [945], 'observations': [947], 'colleagues': [951], 'evidence': [953, 1228], 'novel': [956], 'link': [957], 'between': [958, 1836], 'proatherogenic': [961, 1065, 1267], 'induced': [963], 'oxidase.': [969, 1222], 'multicomponent': [974], 'superoxide-generating': [975], 'thought': [979], 'play': [981], 'atherosclerosis.15': [989], 'relating': [994], 'generation': [1002], 'still': [1005], 'unclear,': [1007], 'protein': [1011, 1597], 'kinase': [1012, 1598], 'C': [1013, 1924, 1927, 1971, 2051, 2054], 'calmodulin': [1015], 'based': [1022], 'inhibition': [1028], 'these': [1030], 'pathways': [1032], 'partially': [1033], 'prevented': [1034], 'homocysteine.One': [1038], 'highly': [1039], 'interesting': [1040], 'aspect': [1041], 'manuscript': [1044], 'et': [1047, 1298, 1303], 'al7': [1048], 'suggestion': [1051], 'activators': [1053, 1077, 1095, 1126, 1254], 'peroxisome': [1055, 1789], 'proliferator-activated': [1056, 1790], 'receptor': [1057, 1758, 1791], 'γ': [1058, 1764, 1792], '(PPARγ': [1059], ')': [1060], 'effectively': [1062], 'prevent': [1063], 'Indeed,': [1071], 'ciglitazone': [1073], 'troglitazone,': [1075], 'PPARγ,': [1079], 'strongly': [1080], 'inhibited': [1081], 'production': [1084, 1703], 'IL-8.': [1088], 'protective': [1090, 1111, 1165, 1250], 'PPARγ': [1094, 1125, 1253], 'appears': [1096], 'their': [1101], 'ability': [1102, 1123], 'attenuate': [1104], 'ROS.': [1109], 'Similar': [1110], 'effects': [1112], 'shown': [1115], 'reduce': [1128], 'components': [1135], 'such': [1136], 'p47phox': [1140, 1146, 1799], 'cells': [1144], 'line.16,17': [1152], 'In': [1153, 1171, 1246], 'addition,': [1154, 1247], 'upregulation': [1156], 'Cu2+,Zn2+-superoxide': [1158, 1766], 'dismutase': [1159, 1767], 'contribute': [1162], 'cells.16': [1170], 'summary,': [1172], 'demonstrates': [1179], 'pathophysiological': [1181], 'relevant': [1182], 'elicit': [1186], 'critically': [1206], 'dependent': [1207], 'involve': [1216], 'This': [1223], 'provides': [1225], 'additional': [1226], 'suggesting': [1229], 'promote': [1234], 'atherogenesis': [1235], 'stimulating': [1237], 'infiltration': [1238], 'leukocytes': [1240], 'injury.': [1245], 'due,': [1257], 'least': [1259], 'part,': [1261], 'attenuation': [1264], 'homocysteine.The': [1270], 'opinions': [1271], 'expressed': [1272], 'editorial': [1275], 'necessarily': [1278], 'those': [1279], 'editors': [1282], 'American': [1286, 2078], 'Heart': [1287], 'Association.FootnotesCorrespondence': [1288], 'Schini-Kerth,': [1292], 'PhD,': [1293], 'Professor': [1294], 'Pharmacology,': [1296], 'Pharmacologie': [1297], 'Physico-Chimie': [1299], 'des': [1300], 'Interactions': [1301], 'Cellulaires': [1302], 'Moléculaires,': [1304], 'Université': [1308], 'de': [1311, 1314, 1865], 'Faculté': [1313], 'Pharmacie,': [1315], '74,': [1316], 'route': [1317], 'du': [1318], 'rhin': [1319], 'B.P.': [1320], '60024,': [1321], '67401': [1322], 'E-mail': [1325], '[email': [1326], 'protected]': [1327], 'References': [1328], '1': [1329], 'KS.': [1331], 'Vascular': [1332, 2115], 'pathology': [1333], 'homocysteinemia:': [1335], 'implications': [1336, 1535], 'arteriosclerosis.': [1341], 'Am': [1342], 'J': [1343, 1358, 1564, 1621, 1681, 1805], 'Pathol.': [1344], '1969;': [1345], '56:': [1346], '111–128.MedlineGoogle': [1347], 'Scholar2': [1348], 'Welsch': [1349], 'GN,': [1350], 'Loscalzo': [1351], 'J.': [1352, 1601], 'atherothrombosis.': [1355], 'N': [1356, 1883], 'Engl': [1357], 'Med.': [1359, 1404], '1998;': [1360, 1405, 1714], '338:': [1361], '1042–1050.CrossrefMedlineGoogle': [1362], 'Scholar3': [1363], 'Boushey': [1364], 'CJ,': [1365], 'Beresford': [1366], 'SAA,': [1367], 'Omenn': [1368], 'GS,': [1369], 'Motulsky': [1370], 'AG.': [1371], 'quantitative': [1373], 'assessment': [1374], 'disease.': [1384, 1401, 1473, 1538, 1731], 'JAMA.': [1385], '1995;': [1386], '27:': [1387], '1049–1057.Google': [1388], 'Scholar4': [1389], 'Refsum': [1390], 'H,': [1391, 1916, 1918, 1920, 1960, 1964], 'Ueland': [1392], 'PM,': [1393, 1514], 'Nygard': [1394], 'O,': [1395, 1993], 'Vollset': [1396], 'SE.': [1397], 'cardiovascular': [1400, 1728], 'Annu': [1402, 1474], 'Rev': [1403, 1475], '49:': [1406], '31–62.CrossrefMedlineGoogle': [1407], 'Scholar5': [1408], 'Jacobsen': [1409], 'DW,': [1410], 'Gatautis': [1411], 'VJ,': [1412], 'Green': [1413], 'R,': [1414, 1510, 1663, 1821, 1995, 2131], 'Robinson': [1415, 1515], 'K,': [1416, 1516, 1689, 2043, 2091, 2127], 'Savon': [1417], 'SR,': [1418, 1609], 'Secic': [1419], 'M,': [1420, 1862, 1914, 1956, 1999, 2003, 2125, 2135], 'Ji': [1421], 'J,': [1422, 1484, 1912, 1966], 'Otto': [1423], 'JM,': [1424], 'Taylor': [1425], 'LM': [1426], 'Jr.': [1427], 'Rapid': [1428], 'HPLC': [1429], 'determination': [1430], 'other': [1435], 'thiols': [1436], 'serum': [1438], 'plasma:': [1440], 'sex': [1441], 'differences': [1442], 'correlation': [1444], 'cobalamin': [1446], 'folate': [1448], 'healthy': [1451], 'subjects.': [1452], 'Clin': [1453, 1622, 1682], 'Chem.': [1454], '1994;': [1455], '40:': [1456], '873–881.CrossrefMedlineGoogle': [1457], 'Scholar6': [1458], 'Kang': [1459], 'SS,': [1460], 'Wong': [1461], 'PW,': [1462], 'Malinow': [1463], 'MR.': [1464], 'Hyperhomocysteinemia': [1465], 'Nutr.': [1476], '192;': [1477], '12:': [1478], '279–298.CrossrefMedlineGoogle': [1479], 'Scholar7': [1480], 'X,': [1482], 'Dai': [1483], 'Remick': [1485], 'DG,': [1486], 'Wang': [1487, 1571, 2139], 'X.': [1488], 'mediated': [1490], 'Circ': [1503, 1732], 'Res.': [1504, 1733], '2003;': [1505, 1567], '93:': [1506], '311–320.LinkGoogle': [1507], 'Scholar8': [1508], 'Poddar': [1509], 'Sivasubramanian': [1511], 'N,': [1512, 1825, 1869, 2093], 'DiBello': [1513], 'Jocobsen': [1517], 'DW.': [1518], 'cells:': [1534, 1592], 'Circulation.': [1539], '2001;': [1540, 1778], '103:': [1541], '2717–2723.CrossrefMedlineGoogle': [1542], 'Scholar9': [1543], 'Zhang': [1544], 'H-S,': [1545], 'Cao': [1546], 'E-H,': [1547], 'Qin': [1548], 'J-F.': [1549], 'redox': [1551], 'status': [1552, 1839], 'modulates': [1553], 'stimulated': [1558], 'cells.': [1563, 1710, 1776], 'Cardiovasc': [1565], 'Pharmacol.': [1566], '42:': [1568], '258–265.CrossrefMedlineGoogle': [1569], 'Scholar10': [1570], 'G,': [1572, 1858, 2049, 2096], 'Siow': [1573, 1694], 'YL,': [1574, 1695], 'O': [1575, 1688], 'K.': [1576], 'nuclear': [1579], 'κB': [1581], 'activity': [1582], 'possible': [1594], 'C.': [1599], 'Biochem': [1600], '2000;': [1602, 1734], '352:': [1603], '817–826.CrossrefMedlineGoogle': [1604], 'Scholar11': [1605], 'Nelken': [1606], 'NA,': [1607], 'Coughlin': [1608], 'Gordon': [1610], 'D,': [1611, 1721, 1871, 2041, 2129], 'Wilcox': [1612], 'JN.': [1613], 'Monocyte': [1614, 2149], 'atheromatous': [1619], 'plaques.': [1620], 'Invest.': [1623, 1683], '1991;': [1624], '88:': [1625], '1121–1127.CrossrefMedlineGoogle': [1626], 'Scholar12': [1627], 'Liu': [1628], 'Y,': [1629], 'Hulten': [1630], 'LM,': [1631], 'Wiklund': [1632], 'O.': [1633], 'Macrophages': [1634], 'isolated': [1635], 'produce': [1640], 'oxysterols': [1643], 'regulatory': [1647], 'function': [1648, 2060], 'production.': [1651], 'Arterioscler': [1652], 'Thromb': [1653], 'Vasc': [1654], 'Biol.': [1655], '1997;': [1656], '17:': [1657], '317–323.CrossrefMedlineGoogle': [1658], 'Scholar13': [1659], 'Harker': [1660], 'LA,': [1661], 'Ross': [1662], 'Slichter': [1664], 'SJ,': [1665], 'Scott': [1666], 'CR.': [1667], 'Homocysteine-induced': [1668], 'arteriosclerosis:': [1669], 'injury': [1674], 'its': [1679], 'genesis.': [1680], '1976;': [1684], '58:': [1685], '731–741.CrossrefMedlineGoogle': [1686], 'Scholar14': [1687], 'Lynn': [1690], 'EG,': [1691], 'Chung': [1692], 'YH,': [1693], 'Man': [1696], 'RYK,': [1697], 'Choy': [1698], 'PC.': [1699], 'Biochim': [1711], 'Biophys': [1712], 'Acta.': [1713], '1393:': [1715], '317–324.CrossrefMedlineGoogle': [1716], 'Scholar15': [1717], 'Griendling': [1718], 'KK,': [1719], 'Sorescu': [1720], 'Ushio-Fukai': [1722], 'M.': [1723], 'oxidase:': [1725], 'biology': [1729], '86:': [1735], '494–501.CrossrefMedlineGoogle': [1736], 'Scholar16': [1737], 'Inoue': [1738], 'I,': [1739], 'Goto': [1740], 'S,': [1741, 1749, 1881], 'Matsunaga': [1742], 'T,': [1743, 1745, 1747, 1751, 1860, 1922], 'Nakajima': [1744], 'Awata': [1746], 'Hokari': [1748], 'Komoda': [1750], 'Katayama': [1752], 'S.': [1753], 'ligands/activators': [1755], 'peroxisome-activated': [1757], 'α': [1759], '(PPAR': [1760], 'α)': [1761], 'PPAR': [1763], 'increase': [1765], 'decrease': [1769], 'message': [1771], 'expressions': [1772], 'primary': [1774], 'Metabolism.': [1777], '50:': [1779], '3–11.CrossrefMedlineGoogle': [1780], 'Scholar17': [1781], 'Von': [1782], 'Knethen': [1783], 'A,': [1784, 1823, 1864, 1879], 'Brüne': [1785], 'Activation': [1787], 'nitric': [1794], 'oxide': [1795], 'monocytes/macrophages': [1797], 'down-regulates': [1798], 'attenuates': [1801], 'burst.': [1804], 'Immunol.': [1806], '2002;': [1807], '169:': [1808], '2619–2626.CrossrefMedlineGoogle': [1809], 'Scholar': [1810], 'Previous': [1811], 'Back': [1812], 'top': [1814], 'Next': [1815], 'FiguresReferencesRelatedDetailsCited': [1816], 'By': [1817], 'Dhiman': [1818], 'P,': [1819, 1867, 1873, 2133], 'Pillai': [1820], 'Wilson': [1822], 'Premkumar': [1824], 'Bharadwaj': [1826], 'B,': [1827], 'Ranjan': [1828], 'V': [1829], 'Rajendiran': [1831], 'S': [1832, 1968], '(2021)': [1833], 'Cross-sectional': [1834], 'probable': [1841], 'postpartum': [1842], 'depression': [1843], 'Indian': [1845], 'women,': [1846], 'BMC': [1847], 'Pregnancy': [1848], 'Childbirth,': [1850], '10.1186/s12884-021-03622-x,': [1851], '21:1,': [1852], 'Online': [1853, 1907, 1951, 1988, 2034, 2086, 2120], 'publication': [1854, 1908, 1952, 1989, 2035, 2087, 2121], 'date:': [1855, 1909, 1953, 1990, 2036, 2088, 2122], '1-Dec-2021.': [1856], 'Rossi': [1857], 'Seccia': [1859], 'Barton': [1861], 'Danser': [1863], 'Leeuw': [1866], 'Dhaun': [1868], 'Rizzoni': [1870], 'Rossignol': [1872], 'Ruilope': [1874], 'L,': [1875, 2001], 'van': [1876], 'den': [1877], 'Meiracker': [1878], 'Ito': [1880], 'Hasebe': [1882], 'Webb': [1885], 'D': [1886], '(2018)': [1887], 'Endothelial': [1888, 1982], 'factors': [1889], 'treatment': [1894], 'chronic': [1896, 2066], 'kidney': [1897], 'Part': [1899], 'II,': [1900], 'Journal': [1901, 1944, 2079, 2113], 'Hypertension,': [1903, 2030], '10.1097/HJH.0000000000001600,': [1904], '36:3,': [1905], '(462-471),': [1906], '1-Mar-2018.': [1910], 'Chiang': [1911], 'Sung': [1913, 1955], 'Yu': [1915], 'Chang': [1917, 1959], 'Kuo': [1919], 'Tsai': [1921], 'Yen': [1923, 1961], 'Chen': [1926, 1963, 1970], '(2011)': [1928], 'through': [1935], 'differential': [1936], 'regulation': [1937], 'cyclins': [1939], 'D1': [1942], 'expression,': [1943], 'Cellular': [1946], 'Physiology,': [1947], '10.1002/jcp.22415,': [1948], '226:4,': [1949], '(1017-1026),': [1950], '1-Apr-2011.': [1954], 'Wu': [1957], 'C,': [1958, 1962, 2039, 2045, 2047], 'Cheng': [1965], 'Chien': [1967], '(2009)': [1972, 2009], 'Shear': [1973], 'Stress': [1974], 'Inhibits': [1975], 'Homocysteine-Induced': [1976], 'Stromal': [1977], 'Cell–Derived': [1978], 'Factor-1': [1979], 'Expression': [1980], 'Cells,': [1983], '105:8,': [1986], '(755-763),': [1987], '9-Oct-2009.': [1991], 'Fridman': [1992], 'Porcile': [1994], 'Vanasco': [1996], 'V,': [1997], 'Junco': [1998], 'Gariglio': [2000], 'Potenzoni': [2002], 'Bañes': [2004], 'I': [2005], 'Morales': [2007], 'Study': [2010], 'Levels': [2013], 'Methylenetetrahydrofolate': [2015], 'Reductase': [2016], 'Gene': [2017], 'Variant': [2018], '(C677T)': [2019], 'Population': [2022], 'Buenos': [2024], 'Aires': [2025], 'City,': [2026], 'Clinical': [2027, 2081], 'Experimental': [2029], '10.1080/10641960802251958,': [2031], '30:7,': [2032], '(574-584),': [2033], '1-Jan-2008.': [2037], 'Antoniades': [2038], 'Tousoulis': [2040], 'Marinou': [2042], 'Vasiliadou': [2044], 'Tentolouris': [2046], 'Bouras': [2048], 'Pitsavos': [2050], 'Stefanadis': [2053], '(2006)': [2055], 'Asymmetrical': [2056], 'dimethylarginine': [2057], 'regulates': [2058], 'methionine-induced': [2062], 'homocystinemia': [2067], 'humans:': [2069], 'cytokines,': [2076], 'Nutrition,': [2082], '10.1093/ajcn/84.4.781,': [2083], '84:4,': [2084], '(781-788),': [2085], '1-Oct-2006.': [2089], 'Akasaka': [2090, 2092], 'Di': [2094], 'Luozzo': [2095], 'Sasajima': [2097], 'T': [2098, 2140], 'Sumpio': [2100], 'B': [2101], '(2005)': [2102], 'promotes': [2104], 'p38-dependent': [2105], 'chemotaxis': [2106], 'bovine': [2108], 'cells,': [2112], 'Surgery,': [2116], '10.1016/j.jvs.2004.12.043,': [2117], '41:3,': [2118], '(517-522),': [2119], '1-Mar-2005.': [2123], 'Shipman': [2124], 'Lubick': [2126], 'Fouchard': [2128], 'Gurram': [2130], 'Grieco': [2132], 'Jutila': [2134], 'Dratz': [2136], 'E': [2137], '(2013)': [2141], 'Proteomic': [2142], 'Systems': [2144], 'Biology': [2145], 'Analysis': [2146], 'Response': [2150], 'Coxiella': [2152], 'burnetii': [2153], 'Infection,': [2154], 'PLoS': [2155], 'ONE,': [2156], '10.1371/journal.pone.0069558,': [2157], '8:8,': [2158], '(e69558)': [2159], 'August': [2160], '22,': [2161, 2173], '2003Vol': [2162], 'Issue': [2164], '4': [2165], 'Advertisement': [2166, 2182], 'Article': [2167], 'InformationMetrics': [2168], 'https://doi.org/10.1161/01.RES.0000089561.87997.CFPMID:': [2169], '12933697': [2170], 'publishedAugust': [2172], '2003': [2174], 'Keywordsmonocyte': [2175], 'protein-1human': [2177], 'monocytesinterleukin-8reactive': [2178], 'specieshomocysteinePDF': [2180], 'download': [2181]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2151499688', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-23T08:58:52.413649', 'created_date': '2016-06-24'}