Becaplermin (Regranex) for Diabetic Foot Ulcers

Name: Work Video:
Duration: 3 min 30 s
Description: Although patients treated with becaplermin are more likely to experience complete and faster ulcer healing than patients continuing good wound care alone, the increased risk of cancer mortality and significant cost outweigh the possible benefits in most patients.
Courtney I. Jarvis
{'id': 'https://openalex.org/W2763046336', 'doi': None, 'title': 'Becaplermin (Regranex) for Diabetic Foot Ulcers', 'display_name': 'Becaplermin (Regranex) for Diabetic Foot Ulcers', 'publication_year': 2008, 'publication_date': '2008-07-15', 'ids': {'openalex': 'https://openalex.org/W2763046336', 'mag': '2763046336'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://www.aafp.org/afp/2008/0715/p255.html', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S154286738', 'display_name': 'American family physician', 'issn_l': '0002-838X', 'issn': ['0002-838X', '1532-0650', '1532-0669'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316112', 'host_organization_name': 'American Academy of Family Physicians', 'host_organization_lineage': ['https://openalex.org/P4310316112'], 'host_organization_lineage_names': ['American Academy of Family Physicians'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5056840197', 'display_name': 'Courtney I. Jarvis', 'orcid': 'https://orcid.org/0000-0003-3660-2217'}, 'institutions': [], 'countries': [], 'is_corresponding': True, 'raw_author_name': 'Courtney I. Jarvis', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5056840197'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.19, 'has_fulltext': False, 'cited_by_count': 5, 'citation_normalized_percentile': {'value': 0.651076, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 78, 'max': 80}, 'biblio': {'volume': '78', 'issue': '2', 'first_page': '255', 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11227', 'display_name': 'Diabetic Foot Ulcer Assessment and Management', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11227', 'display_name': 'Diabetic Foot Ulcer Assessment and Management', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10771', 'display_name': 'Wound Healing and Treatments', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/2742', 'display_name': 'Rehabilitation'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11253', 'display_name': 'Nail Diseases and Treatments', 'score': 0.9301, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/diabetic-foot-ulcer', 'display_name': 'Diabetic foot ulcer', 'score': 0.6719902}, {'id': 'https://openalex.org/keywords/wound-care', 'display_name': 'Wound care', 'score': 0.65573096}, {'id': 'https://openalex.org/keywords/diabetic-ulcers', 'display_name': 'Diabetic ulcers', 'score': 0.51628226}, {'id': 'https://openalex.org/keywords/foot', 'display_name': 'Foot (prosody)', 'score': 0.45118222}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.9927836}, {'id': 'https://openalex.org/C2777858829', 'wikidata': 'https://www.wikidata.org/wiki/Q52856', 'display_name': 'Diabetic foot', 'level': 3, 'score': 0.75841784}, {'id': 'https://openalex.org/C2778144972', 'wikidata': 'https://www.wikidata.org/wiki/Q52859', 'display_name': 'Diabetic foot ulcer', 'level': 4, 'score': 0.6719902}, {'id': 'https://openalex.org/C2993807428', 'wikidata': 'https://www.wikidata.org/wiki/Q25324087', 'display_name': 'Wound care', 'level': 2, 'score': 0.65573096}, {'id': 'https://openalex.org/C177713679', 'wikidata': 'https://www.wikidata.org/wiki/Q679690', 'display_name': 'Intensive care medicine', 'level': 1, 'score': 0.5510269}, {'id': 'https://openalex.org/C2910357528', 'wikidata': 'https://www.wikidata.org/wiki/Q52859', 'display_name': 'Diabetic ulcers', 'level': 4, 'score': 0.51628226}, {'id': 'https://openalex.org/C115076146', 'wikidata': 'https://www.wikidata.org/wiki/Q1651051', 'display_name': 'Foot (prosody)', 'level': 2, 'score': 0.45118222}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.4510481}, {'id': 'https://openalex.org/C555293320', 'wikidata': 'https://www.wikidata.org/wiki/Q12206', 'display_name': 'Diabetes mellitus', 'level': 2, 'score': 0.39813173}, {'id': 'https://openalex.org/C41895202', 'wikidata': 'https://www.wikidata.org/wiki/Q8162', 'display_name': 'Linguistics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C138885662', 'wikidata': 'https://www.wikidata.org/wiki/Q5891', 'display_name': 'Philosophy', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://www.aafp.org/afp/2008/0715/p255.html', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S154286738', 'display_name': 'American family physician', 'issn_l': '0002-838X', 'issn': ['0002-838X', '1532-0650', '1532-0669'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316112', 'host_organization_name': 'American Academy of Family Physicians', 'host_organization_lineage': ['https://openalex.org/P4310316112'], 'host_organization_lineage_names': ['American Academy of Family Physicians'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.78, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3174871388', 'https://openalex.org/W3142752500', 'https://openalex.org/W3005875898', 'https://openalex.org/W2811327717', 'https://openalex.org/W2810539143', 'https://openalex.org/W2790339970', 'https://openalex.org/W2488599819', 'https://openalex.org/W2416054478', 'https://openalex.org/W2245065110', 'https://openalex.org/W2183778486', 'https://openalex.org/W2165914958', 'https://openalex.org/W2133740542', 'https://openalex.org/W2091353803', 'https://openalex.org/W2054993453', 'https://openalex.org/W2041414141', 'https://openalex.org/W2033968681', 'https://openalex.org/W2024445341', 'https://openalex.org/W2014243403', 'https://openalex.org/W1846007835', 'https://openalex.org/W1592767674'], 'abstract_inverted_index': {'Although': [0], 'patients': [1, 16], 'treated': [2], 'with': [3], 'becaplermin': [4], 'are': [5], 'more': [6], 'likely': [7], 'to': [8], 'experience': [9], 'complete': [10], 'and': [11, 28], 'faster': [12], 'ulcer': [13], 'healing': [14], 'than': [15], 'continuing': [17], 'good': [18], 'wound': [19], 'care': [20], 'alone,': [21], 'the': [22, 32], 'increased': [23], 'risk': [24], 'of': [25], 'cancer': [26], 'mortality': [27], 'significant': [29], 'cost': [30], 'outweigh': [31], 'possible': [33], 'benefits': [34], 'in': [35], 'most': [36], 'patients.': [37]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2763046336', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}], 'updated_date': '2024-12-15T05:27:43.682498', 'created_date': '2017-10-20'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
