Publication Information

{'id': 'https://openalex.org/W2810539143', 'doi': None, 'title': 'Cost Effectiveness of Becaplermin Gel on Wound Closure for the Treatment of Pressure Injuries.', 'display_name': 'Cost Effectiveness of Becaplermin Gel on Wound Closure for the Treatment of Pressure Injuries.', 'publication_year': 2018, 'publication_date': '2018-06-01', 'ids': {'openalex': 'https://openalex.org/W2810539143', 'mag': '2810539143', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29809161'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29809161', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5103532826', 'display_name': 'Adrienne M. Gilligan', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Adrienne M Gilligan', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070755970', 'display_name': 'Curtis Waycaster', 'orcid': 'https://orcid.org/0000-0002-5248-4268'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Curtis R Waycaster', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5024652650', 'display_name': 'Catherine T. Milne', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Catherine T Milne', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.825, 'has_fulltext': False, 'cited_by_count': 11, 'citation_normalized_percentile': {'value': 0.788116, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 86, 'max': 87}, 'biblio': {'volume': '30', 'issue': '6', 'first_page': '197', 'last_page': '204'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10771', 'display_name': 'Wound Healing and Treatments', 'score': 0.9948, 'subfield': {'id': 'https://openalex.org/subfields/2742', 'display_name': 'Rehabilitation'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10771', 'display_name': 'Wound Healing and Treatments', 'score': 0.9948, 'subfield': {'id': 'https://openalex.org/subfields/2742', 'display_name': 'Rehabilitation'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12906', 'display_name': 'Surgical Sutures and Adhesives', 'score': 0.9699, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11670', 'display_name': 'Pressure Ulcer Prevention and Management', 'score': 0.9684, 'subfield': {'id': 'https://openalex.org/subfields/3609', 'display_name': 'Occupational Therapy'}, 'field': {'id': 'https://openalex.org/fields/36', 'display_name': 'Health Professions'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/wound-care', 'display_name': 'Wound care', 'score': 0.5416709}, {'id': 'https://openalex.org/keywords/debridement', 'display_name': 'Debridement (dental)', 'score': 0.4761548}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.74578565}, {'id': 'https://openalex.org/C168563851', 'wikidata': 'https://www.wikidata.org/wiki/Q1436668', 'display_name': 'Randomized controlled trial', 'level': 2, 'score': 0.5650337}, {'id': 'https://openalex.org/C2993807428', 'wikidata': 'https://www.wikidata.org/wiki/Q25324087', 'display_name': 'Wound care', 'level': 2, 'score': 0.5416709}, {'id': 'https://openalex.org/C27081682', 'wikidata': 'https://www.wikidata.org/wiki/Q269829', 'display_name': 'Placebo', 'level': 3, 'score': 0.5267265}, {'id': 'https://openalex.org/C2777438270', 'wikidata': 'https://www.wikidata.org/wiki/Q5248564', 'display_name': 'Debridement (dental)', 'level': 2, 'score': 0.4761548}, {'id': 'https://openalex.org/C2777288759', 'wikidata': 'https://www.wikidata.org/wiki/Q4164182', 'display_name': 'Dosing', 'level': 2, 'score': 0.46075875}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.4503667}, {'id': 'https://openalex.org/C535046627', 'wikidata': 'https://www.wikidata.org/wiki/Q30612', 'display_name': 'Clinical trial', 'level': 2, 'score': 0.4382045}, {'id': 'https://openalex.org/C3019080777', 'wikidata': 'https://www.wikidata.org/wiki/Q1754768', 'display_name': 'Cost effectiveness', 'level': 2, 'score': 0.4101323}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.2073108}, {'id': 'https://openalex.org/C112930515', 'wikidata': 'https://www.wikidata.org/wiki/Q4389547', 'display_name': 'Risk analysis (engineering)', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C204787440', 'wikidata': 'https://www.wikidata.org/wiki/Q188504', 'display_name': 'Alternative medicine', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D043925', 'descriptor_name': 'Angiogenesis Inducing Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000077214', 'descriptor_name': 'Becaplermin', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D003668', 'descriptor_name': 'Pressure Ulcer', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D014945', 'descriptor_name': 'Wound Healing', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D043925', 'descriptor_name': 'Angiogenesis Inducing Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D043925', 'descriptor_name': 'Angiogenesis Inducing Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000077214', 'descriptor_name': 'Becaplermin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000077214', 'descriptor_name': 'Becaplermin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003362', 'descriptor_name': 'Cost-Benefit Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003646', 'descriptor_name': 'Debridement', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003668', 'descriptor_name': 'Pressure Ulcer', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003668', 'descriptor_name': 'Pressure Ulcer', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D059039', 'descriptor_name': 'Standard of Care', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014945', 'descriptor_name': 'Wound Healing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29809161', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.49, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3082153399', 'https://openalex.org/W3032124713', 'https://openalex.org/W2554136779', 'https://openalex.org/W2525756941', 'https://openalex.org/W2469117608', 'https://openalex.org/W2407690844', 'https://openalex.org/W2369162477', 'https://openalex.org/W2223461400', 'https://openalex.org/W2167051636', 'https://openalex.org/W2126120186'], 'abstract_inverted_index': {'This': [0], 'study': [1], 'aims': [2], 'to': [3, 31, 237, 242], 'determine': [4], 'the': [5, 15, 90, 111, 117, 135, 157, 166, 206, 222], 'cost': [6, 145, 254, 267], 'effectiveness': [7], 'of': [8, 17, 37, 67, 103, 156, 162, 258, 274], 'becaplermin': [9, 41, 131], 'gel': [10, 42, 54, 82, 248], 'on': [11], 'wound': [12, 38, 47, 57, 64, 251], 'healing': [13, 39], 'for': [14, 40, 110, 130, 169, 173, 213, 217, 221, 272], 'treatment': [16], 'stage': [18, 21], '3': [19], 'and': [20, 35, 71, 81, 147, 171, 219, 268], '4': [22], 'pressure': [23], 'injuries': [24], '(PIs).A': [25], '2-stage': [26], 'Markov': [27, 112], 'model': [28], 'was': [29, 105, 132, 154, 228, 253], 'used': [30, 88], 'predict': [32], 'expected': [33], 'costs': [34, 202, 212], 'outcomes': [36, 262], 'once': [43], 'daily': [44], 'plus': [45, 55, 249], 'good': [46, 56, 63, 250], 'care': [48, 58, 65, 159, 252], '(BGWC)': [49], 'compared': [50, 187], 'with': [51, 180, 188, 197], 'a': [52, 95, 264], 'placebo': [53], '(control)': [59], 'over': [60, 256], '1': [61, 176, 244], 'year;': [62], 'consisted': [66], 'debridement,': [68], 'infection': [69], 'management,': [70], 'moisture': [72], 'balance.': [73], 'Patients': [74, 195], 'in': [75, 89], 'both': [76], 'arms': [77], 'received': [78], 'dressing': [79], 'changes': [80], 'applications': [83], 'twice': [84], 'daily.': [85], 'Outcome': [86], 'data': [87], 'analysis': [91], 'were': [92, 114, 124, 141, 215], 'derived': [93, 125, 142], 'from': [94, 116, 126, 143], '16-week': [96], 'randomized': [97], 'clinical': [98, 118], 'trial.': [99, 119], 'The': [100, 224], 'primary': [101], 'outcome': [102], 'interest': [104], 'PI-free': [106, 185, 246], 'weeks.': [107], 'Transition': [108], 'probabilities': [109], 'states': [113], 'estimated': [115], 'Pressure': [120], 'injury': [121], 'recurrence': [122], 'rates': [123], 'PI': [127, 214], 'literature.': [128], 'Utilization': [129], 'calculated': [133], 'using': [134], "manufacturer's": [136], 'recommended': [137], 'dosing': [138], 'algorithm.': [139], 'Costs': [140], 'standard': [144, 257], 'references': [146], 'medical': [148], 'supply': [149], 'wholesalers;': [150], 'economic': [151], 'perspective': [152], 'taken': [153], 'that': [155, 233], 'long-term': [158], 'facility.A': [160], 'total': [161, 201], '62': [163], 'patients': [164, 178, 190, 234], 'completed': [165], 'study:': [167], '31': [168, 172], 'BGWC': [170, 181, 198, 218], 'control.': [174, 223], 'Over': [175], 'year,': [177], 'treated': [179, 196], 'had': [182], 'substantially': [183], 'higher': [184, 200, 266], 'weeks': [186], 'control': [189, 207], '(11.6': [191], 'vs.': [192], '3.1,': [193], 'respectively).': [194], 'incurred': [199], 'than': [203], 'those': [204], 'receiving': [205], 'treatment.': [208], 'Expected': [209], 'annual': [210], 'direct': [211], '$3827': [216], '$1279': [220], 'incremental': [225], 'cost-effectiveness': [226], 'ratio': [227], '$298': [229, 241], '(about': [230], '$43/day),': [231], 'indicating': [232], 'would': [235], 'have': [236], 'pay': [238], 'an': [239], 'extra': [240], 'gain': [243], 'additional': [245], 'week.Becaplermin': [247], 'effective': [255], 'care,': [259], 'yielding': [260], 'better': [261], 'at': [263], 'slightly': [265], 'should': [269], 'be': [270], 'considered': [271], 'management': [273], 'PIs.': [275]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2810539143', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 1}], 'updated_date': '2024-12-24T08:51:37.337874', 'created_date': '2018-07-10'}