Publication Information

{'id': 'https://openalex.org/W2560099569', 'doi': 'https://doi.org/10.1083/jcb.201607064', 'title': 'B cell antigen extraction is regulated by physical properties of antigen-presenting cells', 'display_name': 'B cell antigen extraction is regulated by physical properties of antigen-presenting cells', 'publication_year': 2016, 'publication_date': '2016-12-06', 'ids': {'openalex': 'https://openalex.org/W2560099569', 'doi': 'https://doi.org/10.1083/jcb.201607064', 'mag': '2560099569', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/27923880', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5223605'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.201607064', 'pdf_url': 'https://rupress.org/jcb/article-pdf/216/1/217/1373975/jcb_201607064.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://rupress.org/jcb/article-pdf/216/1/217/1373975/jcb_201607064.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5056278119', 'display_name': 'Katelyn M. Spillane', 'orcid': 'https://orcid.org/0000-0001-8022-4917'}, 'institutions': [{'id': 'https://openalex.org/I2801081054', 'display_name': 'The Francis Crick Institute', 'ror': 'https://ror.org/04tnbqb63', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I2801081054']}, {'id': 'https://openalex.org/I47508984', 'display_name': 'Imperial College London', 'ror': 'https://ror.org/041kmwe10', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I47508984']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Katelyn M. Spillane', 'raw_affiliation_strings': ['Division of Immunology and Inflammation, Imperial College London, London SW7 2AZ, England, UK 2', 'Immune Receptor Activation Laboratory, The Francis Crick Institute, London NW1 1AT, England, UK 1'], 'affiliations': [{'raw_affiliation_string': 'Immune Receptor Activation Laboratory, The Francis Crick Institute, London NW1 1AT, England, UK 1', 'institution_ids': ['https://openalex.org/I2801081054']}, {'raw_affiliation_string': 'Division of Immunology and Inflammation, Imperial College London, London SW7 2AZ, England, UK 2', 'institution_ids': ['https://openalex.org/I47508984']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5083722680', 'display_name': 'Pavel Tolar', 'orcid': 'https://orcid.org/0000-0003-4693-7299'}, 'institutions': [{'id': 'https://openalex.org/I2801081054', 'display_name': 'The Francis Crick Institute', 'ror': 'https://ror.org/04tnbqb63', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I2801081054']}, {'id': 'https://openalex.org/I47508984', 'display_name': 'Imperial College London', 'ror': 'https://ror.org/041kmwe10', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I47508984']}], 'countries': ['GB'], 'is_corresponding': True, 'raw_author_name': 'Pavel Tolar', 'raw_affiliation_strings': ['Division of Immunology and Inflammation, Imperial College London, London SW7 2AZ, England, UK 2', 'Immune Receptor Activation Laboratory, The Francis Crick Institute, London NW1 1AT, England, UK 1'], 'affiliations': [{'raw_affiliation_string': 'Immune Receptor Activation Laboratory, The Francis Crick Institute, London NW1 1AT, England, UK 1', 'institution_ids': ['https://openalex.org/I2801081054']}, {'raw_affiliation_string': 'Division of Immunology and Inflammation, Imperial College London, London SW7 2AZ, England, UK 2', 'institution_ids': ['https://openalex.org/I47508984']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5083722680'], 'corresponding_institution_ids': ['https://openalex.org/I2801081054', 'https://openalex.org/I47508984'], 'apc_list': None, 'apc_paid': None, 'fwci': 10.411, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 127, 'citation_normalized_percentile': {'value': 0.99995, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '216', 'issue': '1', 'first_page': '217', 'last_page': '230'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11016', 'display_name': 'Monoclonal and Polyclonal Antibodies Research', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11016', 'display_name': 'Monoclonal and Polyclonal Antibodies Research', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10580', 'display_name': 'Immunotherapy and Immune Responses', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10923', 'display_name': 'Force Microscopy Techniques and Applications', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/3107', 'display_name': 'Atomic and Molecular Physics, and Optics'}, 'field': {'id': 'https://openalex.org/fields/31', 'display_name': 'Physics and Astronomy'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/internalization', 'display_name': 'Internalization', 'score': 0.67847574}], 'concepts': [{'id': 'https://openalex.org/C147483822', 'wikidata': 'https://www.wikidata.org/wiki/Q103537', 'display_name': 'Antigen', 'level': 2, 'score': 0.7467826}, {'id': 'https://openalex.org/C139770010', 'wikidata': 'https://www.wikidata.org/wiki/Q1339807', 'display_name': 'Internalization', 'level': 3, 'score': 0.67847574}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.58179045}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.49130884}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.48792192}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.46522993}, {'id': 'https://openalex.org/C67662055', 'wikidata': 'https://www.wikidata.org/wiki/Q1047791', 'display_name': 'Antigen-presenting cell', 'level': 4, 'score': 0.43592873}, {'id': 'https://openalex.org/C4725764', 'wikidata': 'https://www.wikidata.org/wiki/Q844704', 'display_name': 'Extraction (chemistry)', 'level': 2, 'score': 0.43194428}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.40427294}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.35177523}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3337042}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.27275586}, {'id': 'https://openalex.org/C2776090121', 'wikidata': 'https://www.wikidata.org/wiki/Q193529', 'display_name': 'T cell', 'level': 3, 'score': 0.25690413}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.13498223}, {'id': 'https://openalex.org/C43617362', 'wikidata': 'https://www.wikidata.org/wiki/Q170050', 'display_name': 'Chromatography', 'level': 1, 'score': 0.06032881}], 'mesh': [{'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000915', 'descriptor_name': 'Antibody Affinity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017951', 'descriptor_name': 'Antigen Presentation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000941', 'descriptor_name': 'Antigens', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D001402', 'descriptor_name': 'B-Lymphocytes', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D015374', 'descriptor_name': 'Biosensing Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003713', 'descriptor_name': 'Dendritic Cells', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D020566', 'descriptor_name': 'Dendritic Cells, Follicular', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D004548', 'descriptor_name': 'Elasticity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005838', 'descriptor_name': 'Genotype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007145', 'descriptor_name': 'Immunoglobulin kappa-Chains', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D054992', 'descriptor_name': 'Immunological Synapses', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008810', 'descriptor_name': 'Mice, Inbred C57BL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018345', 'descriptor_name': 'Mice, Knockout', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D036103', 'descriptor_name': 'Nanotechnology', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D010641', 'descriptor_name': 'Phenotype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011947', 'descriptor_name': 'Receptors, Antigen, B-Cell', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D013314', 'descriptor_name': 'Stress, Mechanical', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 8, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.201607064', 'pdf_url': 'https://rupress.org/jcb/article-pdf/216/1/217/1373975/jcb_201607064.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5223605', 'pdf_url': 'https://europepmc.org/articles/pmc5223605?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://figshare.com/articles/journal_contribution/B_cell_antigen_extraction_is_regulated_by_physical_properties_of_antigen-presenting_cells/13116803', 'pdf_url': 'https://figshare.com/articles/journal_contribution/B_cell_antigen_extraction_is_regulated_by_physical_properties_of_antigen-presenting_cells/13116803/1/files/25161068.pdf', 'source': {'id': 'https://openalex.org/S4306400572', 'display_name': 'OPAL (Open@LaTrobe) (La Trobe University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I196829312', 'host_organization_name': 'La Trobe University', 'host_organization_lineage': ['https://openalex.org/I196829312'], 'host_organization_lineage_names': ['La Trobe University'], 'type': 'repository'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://kclpure.kcl.ac.uk/portal/en/publications/f18e149f-1001-4209-92dd-7d24785d5b96', 'pdf_url': 'https://kclpure.kcl.ac.uk/portal/files/86210369/B_cell_antigen_extraction_i_SPILLANE_PublishedDecember2016_GOLD_VoR_CC_BY_NC_SA_.pdf', 'source': {'id': 'https://openalex.org/S4306400216', 'display_name': "Research Portal (King's College London)", 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I183935753', 'host_organization_name': "King's College London", 'host_organization_lineage': ['https://openalex.org/I183935753'], 'host_organization_lineage_names': ["King's College London"], 'type': 'repository'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://kclpure.kcl.ac.uk/ws/files/86210369/B_cell_antigen_extraction_i_SPILLANE_PublishedDecember2016_GOLD_VoR_CC_BY_NC_SA_.pdf', 'pdf_url': 'https://kclpure.kcl.ac.uk/ws/files/86210369/B_cell_antigen_extraction_i_SPILLANE_PublishedDecember2016_GOLD_VoR_CC_BY_NC_SA_.pdf', 'source': {'id': 'https://openalex.org/S4306400216', 'display_name': "Research Portal (King's College London)", 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I183935753', 'host_organization_name': "King's College London", 'host_organization_lineage': ['https://openalex.org/I183935753'], 'host_organization_lineage_names': ["King's College London"], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/10044/1/44996', 'pdf_url': 'http://spiral.imperial.ac.uk/bitstream/10044/1/44996/2/4750ABA4-8FAB-4657-B333-E1EE2546A72F.pdf', 'source': {'id': 'https://openalex.org/S4306401396', 'display_name': 'Spiral (Imperial College London)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I47508984', 'host_organization_name': 'Imperial College London', 'host_organization_lineage': ['https://openalex.org/I47508984'], 'host_organization_lineage_names': ['Imperial College London'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223605', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/27923880', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.201607064', 'pdf_url': 'https://rupress.org/jcb/article-pdf/216/1/217/1373975/jcb_201607064.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Peace, justice, and strong institutions', 'score': 0.53, 'id': 'https://metadata.un.org/sdg/16'}, {'display_name': 'Reduced inequalities', 'score': 0.5, 'id': 'https://metadata.un.org/sdg/10'}], 'grants': [{'funder': 'https://openalex.org/F4320307844', 'funder_display_name': 'European Molecular Biology Organization', 'award_id': None}, {'funder': 'https://openalex.org/F4320307874', 'funder_display_name': 'Wellcome', 'award_id': None}, {'funder': 'https://openalex.org/F4320312060', 'funder_display_name': 'Francis Crick Institute', 'award_id': None}, {'funder': 'https://openalex.org/F4320319985', 'funder_display_name': 'Cancer Research UK', 'award_id': None}, {'funder': 'https://openalex.org/F4320334626', 'funder_display_name': 'Medical Research Council', 'award_id': None}, {'funder': 'https://openalex.org/F4320338335', 'funder_display_name': 'H2020 European Research Council', 'award_id': '648228'}], 'datasets': [], 'versions': [], 'referenced_works_count': 45, 'referenced_works': ['https://openalex.org/W1550161690', 'https://openalex.org/W1666706706', 'https://openalex.org/W1840209374', 'https://openalex.org/W1945972342', 'https://openalex.org/W1967139887', 'https://openalex.org/W1976750616', 'https://openalex.org/W1982306166', 'https://openalex.org/W1983090571', 'https://openalex.org/W1988376910', 'https://openalex.org/W1991497659', 'https://openalex.org/W1998712617', 'https://openalex.org/W2001039642', 'https://openalex.org/W2001129308', 'https://openalex.org/W2006392611', 'https://openalex.org/W2008471218', 'https://openalex.org/W2015716478', 'https://openalex.org/W2018521012', 'https://openalex.org/W2019206924', 'https://openalex.org/W2024801021', 'https://openalex.org/W2028087680', 'https://openalex.org/W2030214324', 'https://openalex.org/W203060369', 'https://openalex.org/W2037307064', 'https://openalex.org/W2050216284', 'https://openalex.org/W2054144216', 'https://openalex.org/W2069095331', 'https://openalex.org/W2071380288', 'https://openalex.org/W2080674820', 'https://openalex.org/W2094999215', 'https://openalex.org/W2100427942', 'https://openalex.org/W2102696072', 'https://openalex.org/W2104432354', 'https://openalex.org/W2105336865', 'https://openalex.org/W2114589293', 'https://openalex.org/W2115086955', 'https://openalex.org/W2121686754', 'https://openalex.org/W2123771614', 'https://openalex.org/W2138204597', 'https://openalex.org/W2159476211', 'https://openalex.org/W2162504167', 'https://openalex.org/W2166656748', 'https://openalex.org/W2166711332', 'https://openalex.org/W2396908022', 'https://openalex.org/W4246504300', 'https://openalex.org/W780623460'], 'related_works': ['https://openalex.org/W4366318089', 'https://openalex.org/W4225584766', 'https://openalex.org/W2952148578', 'https://openalex.org/W2764950946', 'https://openalex.org/W2145545797', 'https://openalex.org/W2078432352', 'https://openalex.org/W2068721292', 'https://openalex.org/W2014118959', 'https://openalex.org/W1807798123', 'https://openalex.org/W1585685362'], 'abstract_inverted_index': {'Antibody': [0], 'production': [1], 'and': [2, 11, 38, 60, 106, 116], 'affinity': [3, 108], 'maturation': [4], 'are': [5, 96, 114], 'driven': [6], 'by': [7, 44], 'B': [8, 54, 102, 130, 147], 'cell': [9, 103, 131, 148], 'extraction': [10, 20, 59, 80], 'internalization': [12], 'of': [13, 75, 86, 119, 129, 140, 146], 'antigen': [14, 79, 134], 'from': [15], 'immune': [16], 'synapses.': [17], 'However,': [18], 'the': [19, 83, 87, 126], 'mechanism': [21], 'remains': [22], 'poorly': [23], 'understood.': [24], 'Here': [25], 'we': [26, 51], 'develop': [27], 'DNA-based': [28], 'nanosensors': [29], 'to': [30, 62, 70, 82], 'interrogate': [31], 'two': [32], 'previously': [33], 'proposed': [34], 'mechanisms,': [35], 'enzymatic': [36, 63], 'liberation': [37, 64], 'mechanical': [39, 67, 76, 127], 'force.': [40], 'Using': [41], 'antigens': [42, 121], 'presented': [43], 'either': [45], 'artificial': [46], 'substrates': [47], 'or': [48], 'live': [49], 'cells,': [50], 'show': [52, 91], 'that': [53, 92, 99, 137], 'cells': [55, 95, 98, 113, 142], 'primarily': [56], 'use': [57, 74], 'force-dependent': [58], 'resort': [61], 'only': [65], 'if': [66], 'forces': [68, 77, 105], 'fail': [69], 'retrieve': [71], 'antigen.': [72], 'The': [73], 'renders': [78], 'sensitive': [81], 'physical': [84], 'properties': [85, 128, 139], 'presenting': [88, 141], 'cells.': [89], 'We': [90], 'follicular': [93], 'dendritic': [94, 112], 'stiff': [97], 'promote': [100, 117], 'strong': [101], 'pulling': [104], 'stringent': [107], 'discrimination.': [109], 'In': [110], 'contrast,': [111], 'soft': [115], 'acquisition': [118], 'low-affinity': [120], 'through': [122], 'low': [123], 'forces.': [124], 'Thus,': [125], 'synapses': [132], 'regulate': [133], 'extraction,': [135], 'suggesting': [136], 'distinct': [138], 'support': [143], 'different': [144], 'stages': [145], 'responses.': [149]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2560099569', 'counts_by_year': [{'year': 2024, 'cited_by_count': 17}, {'year': 2023, 'cited_by_count': 20}, {'year': 2022, 'cited_by_count': 15}, {'year': 2021, 'cited_by_count': 17}, {'year': 2020, 'cited_by_count': 16}, {'year': 2019, 'cited_by_count': 20}, {'year': 2018, 'cited_by_count': 15}, {'year': 2017, 'cited_by_count': 6}, {'year': 2016, 'cited_by_count': 1}], 'updated_date': '2025-01-08T21:07:32.678574', 'created_date': '2016-12-16'}