Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2764950946', 'doi': None, 'title': 'Antibody transport and internalization into tumours.', 'display_name': 'Antibody transport and internalization into tumours.', 'publication_year': 1990, 'publication_date': '1990-07-01', 'ids': {'openalex': 'https://openalex.org/W2764950946', 'mag': '2764950946', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2383472', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2149524'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2383472', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5108452375', 'display_name': 'S. Matzku', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210100926', 'display_name': 'Research Institute of Radiology', 'ror': 'https://ror.org/0165m4813', 'country_code': 'BY', 'type': 'facility', 'lineage': ['https://openalex.org/I4210100926']}, {'id': 'https://openalex.org/I223822909', 'display_name': 'Heidelberg University', 'ror': 'https://ror.org/038t36y30', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I223822909']}, {'id': 'https://openalex.org/I17937529', 'display_name': 'German Cancer Research Center', 'ror': 'https://ror.org/04cdgtt98', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I1305996414', 'https://openalex.org/I17937529']}], 'countries': ['BY', 'DE'], 'is_corresponding': False, 'raw_author_name': 'S. Matzku', 'raw_affiliation_strings': ['Institute of Radiology and Pathophysiology, German Cancer Research Center, Heidelberg.'], 'affiliations': [{'raw_affiliation_string': 'Institute of Radiology and Pathophysiology, German Cancer Research Center, Heidelberg.', 'institution_ids': ['https://openalex.org/I4210100926', 'https://openalex.org/I223822909', 'https://openalex.org/I17937529']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035960323', 'display_name': 'Gerhard Moldenhauer', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I17937529', 'display_name': 'German Cancer Research Center', 'ror': 'https://ror.org/04cdgtt98', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I1305996414', 'https://openalex.org/I17937529']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'G. Moldenhauer', 'raw_affiliation_strings': ['German Cancer Research Center (dkfz'], 'affiliations': [{'raw_affiliation_string': 'German Cancer Research Center (dkfz', 'institution_ids': ['https://openalex.org/I17937529']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040005604', 'display_name': 'Holger Kalthoff', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I17937529', 'display_name': 'German Cancer Research Center', 'ror': 'https://ror.org/04cdgtt98', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I1305996414', 'https://openalex.org/I17937529']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'H. Kalthoff', 'raw_affiliation_strings': ['German Cancer Research Center (dkfz'], 'affiliations': [{'raw_affiliation_string': 'German Cancer Research Center (dkfz', 'institution_ids': ['https://openalex.org/I17937529']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037526893', 'display_name': 'Silvana Canevari', 'orcid': 'https://orcid.org/0000-0002-2963-3587'}, 'institutions': [{'id': 'https://openalex.org/I4210156707', 'display_name': 'Fondazione IRCCS Istituto Nazionale dei Tumori', 'ror': 'https://ror.org/05dwj7825', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126', 'https://openalex.org/I4210156707']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'S. Canevari', 'raw_affiliation_strings': ['Fondazione IRCCS Istituto Nazionale dei Tumori'], 'affiliations': [{'raw_affiliation_string': 'Fondazione IRCCS Istituto Nazionale dei Tumori', 'institution_ids': ['https://openalex.org/I4210156707']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110881727', 'display_name': 'M. I. Colnaghi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I17937529', 'display_name': 'German Cancer Research Center', 'ror': 'https://ror.org/04cdgtt98', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I1305996414', 'https://openalex.org/I17937529']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'M. Colnaghi', 'raw_affiliation_strings': ['German Cancer Research Center (dkfz'], 'affiliations': [{'raw_affiliation_string': 'German Cancer Research Center (dkfz', 'institution_ids': ['https://openalex.org/I17937529']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052441330', 'display_name': 'J. Schuhmacher', 'orcid': 'https://orcid.org/0000-0003-0553-3474'}, 'institutions': [{'id': 'https://openalex.org/I17937529', 'display_name': 'German Cancer Research Center', 'ror': 'https://ror.org/04cdgtt98', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I1305996414', 'https://openalex.org/I17937529']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'J. Schuhmacher', 'raw_affiliation_strings': ['German Cancer Research Center (dkfz'], 'affiliations': [{'raw_affiliation_string': 'German Cancer Research Center (dkfz', 'institution_ids': ['https://openalex.org/I17937529']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5014447234', 'display_name': 'H. Bihl', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I17937529', 'display_name': 'German Cancer Research Center', 'ror': 'https://ror.org/04cdgtt98', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I1305996414', 'https://openalex.org/I17937529']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'H. Bihl', 'raw_affiliation_strings': ['German Cancer Research Center (dkfz'], 'affiliations': [{'raw_affiliation_string': 'German Cancer Research Center (dkfz', 'institution_ids': ['https://openalex.org/I17937529']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.308, 'has_fulltext': False, 'cited_by_count': 14, 'citation_normalized_percentile': {'value': 0.757077, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 82, 'max': 83}, 'biblio': {'volume': '10', 'issue': None, 'first_page': '1', 'last_page': '5'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11395', 'display_name': 'Radiopharmaceutical Chemistry and Applications', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11395', 'display_name': 'Radiopharmaceutical Chemistry and Applications', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11016', 'display_name': 'Monoclonal and Polyclonal Antibodies Research', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10755', 'display_name': 'HER2/EGFR in Cancer Research', 'score': 0.9912, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/internalization', 'display_name': 'Internalization', 'score': 0.9961436}], 'concepts': [{'id': 'https://openalex.org/C139770010', 'wikidata': 'https://www.wikidata.org/wiki/Q1339807', 'display_name': 'Internalization', 'level': 3, 'score': 0.9961436}, {'id': 'https://openalex.org/C542903549', 'wikidata': 'https://www.wikidata.org/wiki/Q422248', 'display_name': 'Monoclonal antibody', 'level': 3, 'score': 0.74868065}, {'id': 'https://openalex.org/C207001950', 'wikidata': 'https://www.wikidata.org/wiki/Q141124', 'display_name': 'In vivo', 'level': 2, 'score': 0.64057}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.60505474}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.5993885}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.45228386}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.3565123}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.35563284}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.33659956}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.30418092}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.16662708}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.12353811}, {'id': 'https://openalex.org/C150903083', 'wikidata': 'https://www.wikidata.org/wiki/Q7108', 'display_name': 'Biotechnology', 'level': 1, 'score': 0.079701066}], 'mesh': [{'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D009374', 'descriptor_name': 'Neoplasms, Experimental', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007205', 'descriptor_name': 'Indium Radioisotopes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007457', 'descriptor_name': 'Iodine Radioisotopes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008223', 'descriptor_name': 'Lymphoma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008223', 'descriptor_name': 'Lymphoma', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009374', 'descriptor_name': 'Neoplasms, Experimental', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2383472', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.6, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 30, 'referenced_works': ['https://openalex.org/W1516920931', 'https://openalex.org/W1541278346', 'https://openalex.org/W1551923230', 'https://openalex.org/W1590894521', 'https://openalex.org/W1596160068', 'https://openalex.org/W1599748558', 'https://openalex.org/W1605162359', 'https://openalex.org/W1675602576', 'https://openalex.org/W1763447575', 'https://openalex.org/W1815150347', 'https://openalex.org/W1878414703', 'https://openalex.org/W1904286143', 'https://openalex.org/W1944128175', 'https://openalex.org/W1979627357', 'https://openalex.org/W1984893522', 'https://openalex.org/W1996299434', 'https://openalex.org/W2002645111', 'https://openalex.org/W2011832860', 'https://openalex.org/W2023027189', 'https://openalex.org/W2027076158', 'https://openalex.org/W2034237088', 'https://openalex.org/W2062895505', 'https://openalex.org/W2064525881', 'https://openalex.org/W2090726150', 'https://openalex.org/W2092938566', 'https://openalex.org/W2132408663', 'https://openalex.org/W2145741279', 'https://openalex.org/W2257988791', 'https://openalex.org/W2413616938', 'https://openalex.org/W2417533063'], 'related_works': ['https://openalex.org/W2939843879', 'https://openalex.org/W2094481489', 'https://openalex.org/W2083105637', 'https://openalex.org/W2067193714', 'https://openalex.org/W2060242226', 'https://openalex.org/W1984195133', 'https://openalex.org/W1971628265', 'https://openalex.org/W1969289591', 'https://openalex.org/W1968558040', 'https://openalex.org/W1856085589'], 'abstract_inverted_index': {'Internalization': [0], 'of': [1, 10, 20, 29, 32, 40, 44, 48, 63], 'monoclonal': [2], 'antibody': [3, 25], '(MAb)': [4], 'conjugates': [5], 'is': [6], 'an': [7], 'important': [8], 'feature': [9], 'tumour': [11], 'targeting,': [12], 'both': [13], 'with': [14], 'respect': [15], 'to': [16, 23, 27], 'the': [17, 24, 46, 61], 'therapeutic': [18], 'action': [19], 'substances': [21], 'coupled': [22], 'and': [26, 37, 43, 57], 'retention': [28], 'radionuclides.': [30], 'Problems': [31], 'analysing': [33], 'internalization': [34], 'in': [35, 38, 60], 'vitro': [36], 'vivo,': [39], 'manipulating': [41], 'internalization,': [42], 'evaluating': [45], 'involvement': [47], 'normal': [49], 'tissues': [50], 'are': [51, 58], 'illustrated': [52], 'by': [53], 'recent': [54], 'experimental': [55], 'data': [56], 'discussed': [59], 'light': [62], 'published': [64], 'evidence.': [65]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2764950946', 'counts_by_year': [{'year': 2021, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-17T15:48:52.157264', 'created_date': '2017-10-27'}