Title: Species and drug resistance of Mycobacteriumisolated from sputum smear positive patients
Abstract: Objective To study the species and drug resistance of Mycobacteriumisolated from patients with sputum smear positive for acid-fast bacillus in Wujiang city,and provide reference for the prevention and control of tuberculosis.Methods Sputum specimens with positive smear were cultured,isolated bacteria were identified and performed drug susceptibility testing,drug resistance among different species of strains and between patients with initial and repeated treatment were compared.Results A total of 103 Mycobacteriumisolates were included in the study,13 of which were nontuberculous Mycobacterium,drug resistance rate was 100.00%,multidrug resistance(MDR)rate was 84.62%;90 isolates were Mycobacterium tuberculosis,81(90.00%)of which were Mycobacterium hominis.Drug resistance rate of Mycobacterium tuberculosis was 35.56%,MDR rate was 14.44%.Of 70 initially treated tuberculosis patients with positive sputum smear,14(20.00%)were resistant to drugs,MDR rate was 4.28%(3/70);Of 20 repeatedly treated tuberculosis patients with positive sputum smear,18(90.00%)were resistant to drugs,MDR rate was 50.00%(10/20).Conclusion Mycobacterium tuberculosis is the major isolated strain from patients with positive sputum smear.Drug resistance and MDR rates of nontuberculous Mycobacteriumare very high.Drug resistance and MDR rates of Mycobacterium tuberculosis in repeatedly treated patients are higher than initially treated patients.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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