Title: Expression of Rac1 in colorectal carcinoma tissues
Abstract: Objective To explore the expression and significance of Rac1 in colorectal carcinoma tissues.Methods The expression of Rac1 protein in 75 cases of colorectal carcinoma tissues was detected by immunohistochemical methods(SP).Results Rac1 protein was not expressed in normal large intestine mucous membrane,however,the positive rate of expression of Rac1 protein in colorectal carcinoma tissues was obviously increased(76%).The high expression of Rac1 protein was closely correlated with histological differentiation degree,depth of infiltration and lymph node metastasis of the carcinoma(P0.05).Conclusion The expression of Rac1 protein is increased in colorectal cancer tissues,and the high expression of Rac1 protein may promote the invasion and metastasis of colorectal carcinoma.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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