Title: Correlation between aortic distensibility variation and left ventricular concentric remodeling in patients with primary hypertension
Abstract: Objective To evaluate the variation of aortic distensibility and its relation with left ventricular concentric remodeling in patients with primary hypertension.Methods Using two-dimensional and Doppler echocardiography,aortic distensibility (AD) and relative wall thickness (RWT),a parameter of left ventricular concentric remodeling were measured in 23 normal subjects (control group) and 32 patients with primary hypertension (hypertensive group).Taking the mean- 1.645 s of control group as the normal cut off value of AD,the hypertensive group was divided into two subgroups: group I with AD value lower than normal and group II within the normal range.Related clinical variables and echo parameters were compared between the two groups and stepwise regression was made to determine the relationship between AD and RWT.Results AD of hypertensive group was lower than that of control group; Univariate analysis showed that AD was significantly related to RWT,age and systolic blood pressure in hypertensive group; Multivariate regression demonstrated that RWT,age and systolic blood pressure entered the regression equation.Conclusions Aortic distensibility decreased in patients with hypertension and its reduction showed close relations with concentric remodeling of left ventricle,aging and increased systolic blood pressure.
Publication Year: 2003
Publication Date: 2003-01-01
Language: en
Type: article
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