Title: A study on left ventricular systolic function in patients with essential hypertension using quantitative tissue velocity imaging
Abstract: Objective To explore the change of systolic long-axis left ventricular function in asymptomatic hypertensive patients.Methods 98 essential hypertensive patients with no heart failure were divided into three groups: group I,39 without left ventricular hypertrophy;group II,43 with left ventricular hypertrophy;group III,16 essential hypertensive patients with diastolic heart failure.And thirty-nine healthy subjects were randomly selected.No significant differences between groups in LV ejection fraction were noted.QTVI-derived peak velocity(Sa,Ea and Aa) was measured at mitral annulus(septal and lateral),and mean peak velocity was calculated by averaging data.Results Mean Sa levels in the group II and group III were significantly lower than that in healthy subjects and group I.Mean Sa levels in the group II was significantly lower than that in the group III.Comparing with that in group I,group II and group III,the mean Ea levels decreased progressively from the normal control subjects.Using multivariable linear regression analysis,mean Ea(P0.0001),mean Aa(P0.0001),and female gender(P0.005) were found to be independent predictors of Sa.Conclusion Systolic long-axis LV function is impaired in hypertensive patients without symptom and/ or syndrome of heart failure.The systolic and diastolic LV function of hypertensive patients are correlated and interactive.The assessment of LV longitudinal function by QTVI plays an important role in identifying not only diastolic dysfunction,but also sub clinical LV systolic dysfunction.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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