Title: Preparation of 2-Ethoxycarbonyl-3-bromo-4-methyl-5-formylpyrrole
Abstract:2-Ethoxycarbonyl-3-bromo-4-methyl-5-formyl-pyrrole,an important intermediate of tolyporphin A,is prepared from 2-ethoxycarbonyl3-bromo-4,5-dimethyl-pyrrole by selective oxidation with ceric ammonium n...2-Ethoxycarbonyl-3-bromo-4-methyl-5-formyl-pyrrole,an important intermediate of tolyporphin A,is prepared from 2-ethoxycarbonyl3-bromo-4,5-dimethyl-pyrrole by selective oxidation with ceric ammonium nitrate(CAN).Thus,with CAN and the substrate in mole ratio 4.2∶1,reacting at 0 ℃ for 1.5 h,the maximum yield(94.2%) of the product was obtained.Read More
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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