Title: The clinical value of combination of transcatheter superselective intra-arterial chemotherapy in the combined treatment of advanced nasopharyngeal carcinoma
Abstract: Objective To evaluate the clinical value of selective arterial chemotherapy after radiotherapy for advanced nasopharyngeal carcinoma (stageⅢ,Ⅳa). Methods Sixty patients with advanced nasopharyngeal carcinoma were randomized to receive either combined elective arterial chemotherapy and radiotherapy (IACT group, 30 patients) or combined general intravenous chemotherapy and radiotherapy(IVCTgroup, 30 patients). Four weeks after radiotherapy, the effect of two methods was compared. Results The efficiency rate and the 1-year local disease control rate were 93.33 %, 92.86 % in IACT and 70.00 %, 71.43 % in IVCT, respectively. There were outstanding differences between the two groups(P 0.05). Conclusion The short-term therapeutic results of selective arterial chemotherapy combined with radiotherapy in advanced nasopharyngeal carcinoma was obviously effective, the local control rate were high, the side effect were slight.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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