Title: Therapeutic effect of Mixture of Salvia miltiorrhiza and Rhubarb on Severe acute pancreatitis(SAP) intestinal endotoxemia in rats
Abstract: Objective To investigate therapeutic effect of Mixture of Salvia miltiorrhiza and Rhubarb on Severe acute pancreatitis(SAP) intestinal endotoxemia.Methods Devide 30 Wistar rats into 3 groups named Sham Operation group(SO) and Model group and Theraphy group randomly and equally,set Model group and Threapy group as SAP model,intervene Theraphy group with Mixture of Salvia miltiorrhiza and Rhubarb,detect every group's TNF-α,IL-6,ET,DAO in blood 12 hours later.Result TNF-α,IL-6,ET,DAO of Model group is higher than SO group,but these index are lower after intervene by Mixture of Salvia miltiorrhiza and Rhubarb.Conclusion Mixture of Salvia miltiorrhiza and Rhubarb can protect Intestinal mucosa,it is benefit for treatment of Severe acute pancreatitis intestinal endotoxemia.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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