Title: Effect of Zhibai Yangyin Decoction on Glucose and Lipid Metabolism of Rats with Yin-deficiency Induced by Glucocorticosteroid
Abstract: ObjectiveTo observe the effect of Zhibai Yangyin Decoction on glucose and lipid metabolism of rats with Yin-deficiency induced by glucocorticosteroid. MethodsThirty SD rats were randomly divided into three groups: normal control group,model group and TCM treatment group(n=10).The Yin deficient model was induced by glucocorticosteroid,and the TCM group were administered intragastrically with Zhibai Yangyin Decoction.After 8 days,all rats were executed the concentrations of total cholesterol(CHOL),triglyceride(TG),high density lipoprotein cholesterol(HDL-C),low density lipoprotein-cholesterol(LDL-C) and blood sugar(BS) were determined. ResultsCompared with the normal control group,the concentrations of GLU,TG,CHOL,HDL-C were higher in the other groups(P0.05).Compared with the model group,the concentration of GLU,CHOL,TG,HDL-C,LDL-C were decreased in the TCM group while GLU、CHOL were more significantly decreased(P0.05). ConclusionThere are some degree disorders of glucose and lipid metabolism in rats with Yin-deficiency induced by glucocorticosteroid.Zhibai Yangyin Decoction can improve the symptoms of Yin-deficiency,and lower the glucose and lipid metabolism of rats with Yin-deficiency caused by glucocorticosteroid.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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