Title: Analysis of clinical therapeutic effect and serum concentration carbamazepine for the children in northeast region
Abstract: OBJECTIVE To determine carbamazepine in children serum after taking carbamazepine orally,and analysis the relationship between serum concentration and clinical therapeutic effect.METHODS To use FPIA for determination of carbamazepine in children serum;to evaluate clinical therapeutic effect of carbamazepine;to analyze the relationship among serum concentration、daily dose、total daily dose and clinical therapeutic effect.RESULTS The therapeutic effect was satisfactory when the serum concentration was in the range of 4.0-12.0 mg·L-1.CONCLUSION Carbamazepine serum concentration shouled be controlled in the ranges of 4.0-12.0 mg·L-1 as far as possible in clinical medication,the dependability between clinical therapeutic effect and serum concentration is superior to the dependability between dose and serum concentration.
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot