Title: Effects of resveratrol on the proliferation and cell cycle of lymphoma BJAB cell in vitro
Abstract:Objective: To confirm the inhibiting effects of resveratrol(Res) on the proliferation of lymphoma BJAB cell in vitro, and to analyze the variation of the cell cycle of BJAB cell influenced by Res. Met...Objective: To confirm the inhibiting effects of resveratrol(Res) on the proliferation of lymphoma BJAB cell in vitro, and to analyze the variation of the cell cycle of BJAB cell influenced by Res. Methods: Different densities of Res were used applied to BJAB cells,and the morphologic changes of BJAB cell at 24,48,72 h were observed. The MTT assay was used to observe the inhibiting effects of Res on the cell proliferation. The flow cytometry(FCM) was adopted to investigate the influence of Res on the cell cycle. Results: Conspicuous inhibiting effects of Res on the proliferation of BJAB cell were observed. The effect was positively correlated with the density and action time of Res. The cell cycle of BJAB cell changed, it showed the retardant of stage G1, and the quantity of cell decreased in stage S and G2.Conclusion: Res can significantly inhibit the proliferation of BJAB cell caused by retardant of stage G1 and the cell cycle of BJAB cell is intervened by Res.Read More
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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