Title: Suppressing growth and inducting apoptosis of Resveratrol on C6 cell
Abstract:Objective To investigate the suppressive effect of Resverol(Res) on proliferation of C6 cell. Methods Res at various concentrations were used to process the C6 cell; the inhibitory action on the growt...Objective To investigate the suppressive effect of Resverol(Res) on proliferation of C6 cell. Methods Res at various concentrations were used to process the C6 cell; the inhibitory action on the growth of C6 cell was evaluated through MTT assay. The cell cycle distribution change and apoptosis induced by Res were examined through flow cytometer (FCM). In addition, the electron microscope was applied to observe the change of the cell's ultra microstructure. Results The experiment showed that Res could suppress the growth and multiplication of C6 cell in a doesand time-dependent manner. Simultaneously Res could effect the C6 cell's cycle distribution, block the cell advancing from G1 to S period. In the experiment the C6 cell apoptosis was induced by Res and the ultra microstructure of C6 cell changed. Conclusion Res obviously suppressed the proliferation of C6 cell and induced its apoptosis and change the cell cycle.Read More
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot