Title: Clinical Studies on Tripterygium Wilfordii Film for Osteoarthritis of Knees
Abstract: [Objective] To compare the effect and safety between Tripterygium Wilfordii Film (TNF) and Compound Tripterygium Wilfordii Film (CTWF) for osteoarthritis of knees. The latter was mainly composed of Radix Folium seu Flos Tripterygii Wilfordii, Rhizoma Chuanxiong, Olibanum, Myrrha, etc. [Methods] Sixty cases of osteoarthritis of knees were randomized to two groups: group A (30 cases) treated with CTWF and group B (30 cases) with TWF. Both of the two groups were given oral use of herbal medicine on the basis of syndrome differentiation. Pain and stiffness of the knees and knee function were observed before and after treatment and their side reactions were also observed. [Results] Pain and stiffness of the knees and the impaired function were relieved in both groups ( P 0.01 compared with those before treatment) . Two weeks after treatment, the effect of CTWF in improving knee pain, impaired function and WOMAC scoring was better than that of TWF ( P 0.01). The results of safety evaluation in one third of the cases showed that no obvious side effects were found. [Conclusion] CTWF and TWF are both effective and safe in treating osteoarthritis of knees, but the former is superier to the latter.
Publication Year: 2004
Publication Date: 2004-01-01
Language: en
Type: article
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