Title: Significance of serum homocysteine, bilirubin and uric acid detection in patients with coronary heart disease
Abstract: OBJECTIVE To discuss the significance of serum homocysteine, bilirubin and uric acid in detecting patients with coronary heart disease. METHODS From January 2010 to December 2011, the serum levels of homocysteine, bilirubin and uric acid in 600 cases with coronary heart disease (CHD) [132 cases with stable angina pectoris (SAP), 171 cases with un- stable angina pectoris (UAP), 153 cases with non-Q-wave myocardial infarction (NQMI) and 144 cases with Q-wave myocar- dial infarction (QMI)] and 300 cases healthy controls were detected by particles enhance the immune turbidimetric method and enzymatic cycling method, respectively. RESULTS The levels of serum homocysteine, bilirubin and uric acid in CHD group were significantly higher than those in control group (P﹤0.05). The levels of serum homocysteine,, bilirubin and uric acid in UAP group were significantly higher than those in SAP group (P﹤0.05). The levels of serum homocysteine, bilirubin and uric acid in QMI group and NQMI group were significantly higher than those in UAP group and SAP group (P ﹤ 0.05) , while no significant difference was found between QMI group and NQMI group ( P ﹥ 0.05). CONCLUSION The serum homocysteine, bilirubin and uric acid have important significance for diagnosing CHD and judging ill states, and lowing their concentration ear- ly is good for delaying the development of atherosclerosis.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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