Title: Hyperhomocysteinemia as a risk factor for stroke and coronary disease: a case-control follow-up study
Abstract: AIM To examine whether an elevation of total plasma homocysteine is a risk factor for coronary heart disease and stroke. METHODS The study involved 173 patients with hyperhomocysteinemia and selected healthy subjects of matching age and sex. The incidence of coronary disease and stroke was observed during the one-year follow up. RESULTS The incidence of coronary disease was 3.6% in hyperhomocysteinemia patients and 0.6% in the control(RR:3.0,95% CI: 0.4 to 5.5, P0.05), and that of stroke was 4.1% in the patients and 0.6% in the control(RR:3.5,95%CI:0.7 to 6.4, P 0.05). Both coronary disease and stroke occurred in 7.7% of the patients, while in 1.2% of the healthy subjects ( RR:6.4, 95% CI:2.7 to 10.1, P0.01). CONCLUSION Hyperhomocysteinemia is a risk factor for coronary disease and stroke.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot